两亲性二茂铁衍生物的合成及其性质表征
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摘要
二茂铁(ferrocene)衍生物具有独特的结构和光电性质,在电化学、材料科学、分子器件、催化、生物医学等方面有广泛的应用。本论文合成了系列两亲性的二茂铁基衍生物并研究了电化学性质及成膜性能,研究内容如下:
1、设计并合成了系列新型两亲性分子N-长链烷基二茂铁基甲胺,碘化N,N-二甲基长链烷基二茂铁基甲铵盐,1,1'-N,N-长链烷基二茂铁基甲胺,1,1'-碘化N,N-二甲基长链烷基二茂铁基甲铵盐。
2、利用循环伏安法(CV)、常规脉冲法(NPV)、计时电流法(CA)、计时电量法(CC)等多种电化学技术研究了两亲性二茂铁衍生物的电化学性质。研究结果表明:二茂铁基甲铵盐中的二茂铁基的矢量电位显著变化,并且茂环上H原子取代情况对矢量电位影响较大,但是N原子上连结的烷基链的长短对矢量电位影响较小,此外,讨论了不同取代基对化合物的电极过程动力学参数的影响。
3、制备了两种两亲性二茂铁基甲铵盐化合物2b、4b注膜修饰电极。运用循环伏安、差示脉冲等电化学方法研究了修饰电极的电化学性质,得到了修饰电极的动力学参数,为其在电化学传感器方面的应用提供依据。
4、研究了二茂铁衍生物的气液界面行为,发现它们能够形成稳定的Langmuir膜。利用紫外-可见吸收光谱研究了化合物Langmuir-Blodgett(LB)膜的转移情况,利用原子力显微镜观察了单层LB膜的表面形貌,用光学测厚仪测得了单层膜的厚度并推测了化合物在基板上的空间取向及聚集状态。利用化合物3c LB膜修饰电极,考察了LB膜电极与DNA之间的相互作用,为其在生物医药和电化学传感器方面的应用提供理论依据。
Ferrocenyl derivatives are used widely in electrochemistry,material science, molecular device,biomedicine,and catalysis due to the sandwich structures and the photoelectricity character of ferrocene.In this paper,ferrocenyl derivatives were synthesized and their electrochemistry and their Langmuir-Blodgett(LB) films characterization were investigated.
1.Series of new amphiphilic Fc moiety derivatives have been synthesized,such as N-ferrocenylmethylalkylamine,N,N-dimethyl-ferrocenylalkylammonium iodide, 1,1'-N,N-ferroeenylmethylalkylamine,1,1'-N,N-dimethyl-ferrocenylalkyl-ammonium iodide.
2.The electrochemical properties of these compounds were investigated by electrochemical methods such as cyclic voltammetry,normal pulse voltammetry, chronoamperometry and chronocoulometry.Results showed that the redox character affected by the substituent on the H atom in Fc and the half-wave potential E~0 was not almost affected by the substituent on the N atom.The dynamical parameters of electrode process affected by the substituent were also investigated.
3.Electrode modified with two new amphiphilic ferrocenyl derivatives 2b and 4b casted film were made.The electrochemical properties and dynamical parameters of modified electrode were investigated with electrochemical methods such as cyclic voltammetry,differential pulse voltammetry.The results provided some useful information for voltammetric sensors designed appliation.
4.The Langmuir monolayer film and Langmuir-Blodgett(LB) films of these new amphiphilic ferrocenyl derivatives were fabricated.The gas/liquid interface behavior of these compounds was investigated.The results showed that ferrocenyl derivatives could form stable monolayer film at the air/water interface.The multilayer behavior of the ferrocenyl derivatives was examined by UV spectra,the morphology of monolayer was observed by AFM,the thickness of one-layer LB film was measured and the mode in the films was presumed.Electrode modified with 3c LB films was fabricated and the interaction of 3c LB films modified electrode and DNA was researched,which provided some information for biomedicine and sensors.
1、设计并合成了系列新型两亲性分子N-长链烷基二茂铁基甲胺,碘化N,N-二甲基长链烷基二茂铁基甲铵盐,1,1'-N,N-长链烷基二茂铁基甲胺,1,1'-碘化N,N-二甲基长链烷基二茂铁基甲铵盐。
2、利用循环伏安法(CV)、常规脉冲法(NPV)、计时电流法(CA)、计时电量法(CC)等多种电化学技术研究了两亲性二茂铁衍生物的电化学性质。研究结果表明:二茂铁基甲铵盐中的二茂铁基的矢量电位显著变化,并且茂环上H原子取代情况对矢量电位影响较大,但是N原子上连结的烷基链的长短对矢量电位影响较小,此外,讨论了不同取代基对化合物的电极过程动力学参数的影响。
3、制备了两种两亲性二茂铁基甲铵盐化合物2b、4b注膜修饰电极。运用循环伏安、差示脉冲等电化学方法研究了修饰电极的电化学性质,得到了修饰电极的动力学参数,为其在电化学传感器方面的应用提供依据。
4、研究了二茂铁衍生物的气液界面行为,发现它们能够形成稳定的Langmuir膜。利用紫外-可见吸收光谱研究了化合物Langmuir-Blodgett(LB)膜的转移情况,利用原子力显微镜观察了单层LB膜的表面形貌,用光学测厚仪测得了单层膜的厚度并推测了化合物在基板上的空间取向及聚集状态。利用化合物3c LB膜修饰电极,考察了LB膜电极与DNA之间的相互作用,为其在生物医药和电化学传感器方面的应用提供理论依据。
Ferrocenyl derivatives are used widely in electrochemistry,material science, molecular device,biomedicine,and catalysis due to the sandwich structures and the photoelectricity character of ferrocene.In this paper,ferrocenyl derivatives were synthesized and their electrochemistry and their Langmuir-Blodgett(LB) films characterization were investigated.
1.Series of new amphiphilic Fc moiety derivatives have been synthesized,such as N-ferrocenylmethylalkylamine,N,N-dimethyl-ferrocenylalkylammonium iodide, 1,1'-N,N-ferroeenylmethylalkylamine,1,1'-N,N-dimethyl-ferrocenylalkyl-ammonium iodide.
2.The electrochemical properties of these compounds were investigated by electrochemical methods such as cyclic voltammetry,normal pulse voltammetry, chronoamperometry and chronocoulometry.Results showed that the redox character affected by the substituent on the H atom in Fc and the half-wave potential E~0 was not almost affected by the substituent on the N atom.The dynamical parameters of electrode process affected by the substituent were also investigated.
3.Electrode modified with two new amphiphilic ferrocenyl derivatives 2b and 4b casted film were made.The electrochemical properties and dynamical parameters of modified electrode were investigated with electrochemical methods such as cyclic voltammetry,differential pulse voltammetry.The results provided some useful information for voltammetric sensors designed appliation.
4.The Langmuir monolayer film and Langmuir-Blodgett(LB) films of these new amphiphilic ferrocenyl derivatives were fabricated.The gas/liquid interface behavior of these compounds was investigated.The results showed that ferrocenyl derivatives could form stable monolayer film at the air/water interface.The multilayer behavior of the ferrocenyl derivatives was examined by UV spectra,the morphology of monolayer was observed by AFM,the thickness of one-layer LB film was measured and the mode in the films was presumed.Electrode modified with 3c LB films was fabricated and the interaction of 3c LB films modified electrode and DNA was researched,which provided some information for biomedicine and sensors.
引文
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