基于ACIS的数字化适形铅模设计技术研究
摘要
为了保证肿瘤放射治疗的效果,要求在治疗肿瘤的同时尽量降低对健康细胞的损害,控制放射线覆盖范围达到一定的精确程度,即采用适形放疗。目前,临床上采用的多叶光栅和铸造铅模适形方法不能保证适形的精确性,同时又有各自的缺点。本文将计算机辅助设计技术应用到数字化适形铅模的设计过程中,克服上述两种方法的缺点,提高适形精度。
论文结合数字化射野适形铅模技术的开发,对其中的适形铅模设计技术进行研究。针对适形铅模的几何形状,采用B-样条曲线和直纹面的数学模型表述铅模端面曲线和侧面,结合所使用放疗设备的结构参数,用参数设计的方法,确定铅模上下表面的轮廓,得到适形铅模的数学模型。
论文针对制模技师的实际需要开发了基于ACIS的数字化适形铅模设计系统。系统采用面向对象的编程方法进行分析和设计,将问题域的铅模模型和软件系统中的模型直接映射,并使用动态链接库技术实现软件功能,利用精确几何造型平台ACIS强大的造型功能,实现适形铅模的造型和可视化的用户界面。
最后,以人体心脏的X光片轮廓为例,实际验证了本文开发的该设计技术和软件,输出结果表明该软件达到了成像可靠,运算速度高,简单易用的目标。
Radiotherapy is a branch of medical science which uses radiation, predominantly to treat malignant disease. The aim of radiotherapy technique is to improve the carcinogenic cell destruction while reducing at best the undesirable effects onto the neighboring healthy tissue. Conformal radiotherapy can reach this aim perfectly. One way to treat carcinogenic cell is coupled grating, the other is casting lead block. Unfortunately, there are disadvantages in these two methods respectely. To overcome these problems the digital conformal lead block technology is proposed, and computer aided design technology is applied in the field in this dissertation.
The technology for designing the conformal lead block is a part of technique development work of the digital conformal lead block technology. The dissertation points out two important sections in design stage, which includes modeling and ACIS based structuring. According to characters of the conformal lead block shape,ruled surface and B-Spline curve are used to express the side shape of the conformal lead block and profiles of the two end planes, respectively.
In the dissertation, the system for ACIS based conformal lead block design technology has been developed and the aim is at the actual demand of the clinic equipment. The system is designed with the object-oriented theory, and is realized by means of programming language Visual C++6.0 and graphics software ACIS.
In the last step, with a practical machining sample application to the technology development, the system is prove to be accurate and feasible in this paper.
论文结合数字化射野适形铅模技术的开发,对其中的适形铅模设计技术进行研究。针对适形铅模的几何形状,采用B-样条曲线和直纹面的数学模型表述铅模端面曲线和侧面,结合所使用放疗设备的结构参数,用参数设计的方法,确定铅模上下表面的轮廓,得到适形铅模的数学模型。
论文针对制模技师的实际需要开发了基于ACIS的数字化适形铅模设计系统。系统采用面向对象的编程方法进行分析和设计,将问题域的铅模模型和软件系统中的模型直接映射,并使用动态链接库技术实现软件功能,利用精确几何造型平台ACIS强大的造型功能,实现适形铅模的造型和可视化的用户界面。
最后,以人体心脏的X光片轮廓为例,实际验证了本文开发的该设计技术和软件,输出结果表明该软件达到了成像可靠,运算速度高,简单易用的目标。
Radiotherapy is a branch of medical science which uses radiation, predominantly to treat malignant disease. The aim of radiotherapy technique is to improve the carcinogenic cell destruction while reducing at best the undesirable effects onto the neighboring healthy tissue. Conformal radiotherapy can reach this aim perfectly. One way to treat carcinogenic cell is coupled grating, the other is casting lead block. Unfortunately, there are disadvantages in these two methods respectely. To overcome these problems the digital conformal lead block technology is proposed, and computer aided design technology is applied in the field in this dissertation.
The technology for designing the conformal lead block is a part of technique development work of the digital conformal lead block technology. The dissertation points out two important sections in design stage, which includes modeling and ACIS based structuring. According to characters of the conformal lead block shape,ruled surface and B-Spline curve are used to express the side shape of the conformal lead block and profiles of the two end planes, respectively.
In the dissertation, the system for ACIS based conformal lead block design technology has been developed and the aim is at the actual demand of the clinic equipment. The system is designed with the object-oriented theory, and is realized by means of programming language Visual C++6.0 and graphics software ACIS.
In the last step, with a practical machining sample application to the technology development, the system is prove to be accurate and feasible in this paper.
引文
[1]詹海生,李广鑫,马志欣,基于 ACIS 的几何造型技术与系统开发,北京:清华大学出版社,2002-06-01
[2]本书编委会,Visual C++编程篇,北京:电子工业出版社,2005-05
[3]谭浩强,C 程序设计,北京:清华大学出版社,1997-08
[4]林锐, 韩永泉,高质量程序设计指南 C++/C 语言,北京:电子工业出版社,2005-05
[5]李佳,计算机辅助设计与制造,天津:天津大学出版社,2003-09
[6]Mastering CAD/CAM,Ibrahim Zeid Northeastern University. Singapore:McGRAW.HILL INTERNATIONAL EDITION,2005
[7]李佳,用于放射治疗的数字化射野适形铅模制作技术,国家发明专利申请号:200510013909.1
[8]卫炜,基于 ACIS 几何平台 CAD 系统开发与应用的初步实践: [硕士学位论文],南京;南京航空航天大学,2000
[9]王同胜,张连芳,王平,赵政,赵文钦,计算机技术及应用基础,天津:天津大学出版社,2004-04-01
[10]胡逸民,适形放疗——肿瘤放射物理学的新进展,实用肿瘤杂志,2000, 15(4):221-223
[11]邱学军,史荣,冯宁远,杨伟志,立体定向适形放疗的几个重要技术问题,中华肿瘤杂志,2000,22(5):420-421
[12]洪卫,适形放疗发展综述,实用癌症杂志,2003,18(4):439-440
[13]惠周光,殷蔚伯,二十一世纪的放射治疗——调强适形放疗,癌症进展,2003,1:14-19
[14]张水泉,石登正,曾达夫,调强适形放疗的技术和设备,现代医学仪器与应用,1999,44(4):12-13
[15]Mohan R, Barest G, Brewster LJ, et, A comprehensive three-dimensional radiation treatment planning system,Int J Radiat Oncol Biol Phys,1988,15(4):481-484
[16]胡逸民,谷铣之,适形放射治疗——肿瘤放射治疗新技术进展,肿瘤防治杂志,1998,5(4):243-245
[17]胡逸民,放射物理在肿瘤治疗中的地位与作用,中国肿瘤,1995,4(6):9-10
[18]王伟学,精确适形铅模系统的应用及改良,浙江医学,2004,26(10):759
[19]陈康,王捷,二维自动切割机制作肿瘤适形放疗档块在肿瘤放射治疗中的应用,医疗卫生装备,2004,8:54-55
[20]吴登梅,放疗适用于那些肿瘤,卫生与生活报,2004-05-03
[21]王闯,戴建荣,胡逸民,射野方向优化方法,中华放射肿瘤学杂志,2004,13(2):104-106
[22]Moore C.J.,Computerised conformal radiation therapy-a critical process,Computing & Control Engineering Journal,1995,6(5):205-210
[23]包尚联,用于肿瘤诊断和放疗的医学影像学研究,中国生物医学工程学会第六次会员代表大会学术会议论文摘要汇编,2004
[24]胡逸民,肿瘤靶向放射治疗——放射治疗的新方向,第一届中国肿瘤靶向治疗技术大会论文集,2003
[25]Jack J,3D Radiation therapy treatment planning: overview and assessment, Radiother Oncol,1999,13(2):331-336
[26]Purdy JA, Harms WB, Matthews J W, et al. Andvances in 3-D radiation treatment planning system: room-view display with real time interactivity,Int J Radiat Oncol Biol Phys,1993,27(7):933-935
[27]Bortfeld T,Schlegel W,Optimization of beam orientateon in radiateon therapy: some theoretical consideration,Phys Med Biol,1993,38: 291-304
[28]胡逸民,三维剂量计算模型和治疗计划方案优化,肿瘤放射物理学,北京:原子能出版社,1999
[29]Baudet V,Villard P.-F,Jaillet F,Beuve M,Shariat B,Towards accurate tumour tracking in lungs,Information Visualization,2003,IV 2003. Proceedings. Seventh International Conference on 16-18 July 2003 :338-343
[30]万凯,何援军,基于 ACIS 平台的大型三维 CAD 系统的设计与开发,计算机仿真,2004,10
[31]董洪伟,周儒荣,周来水,周弈,在 ACIS 平台上开发三维软件,计算机辅助工程,2002,4:
[32]安鲁陵,基于 ACIS 几何平台的 CAD/CAM 软件开发关键技术研究:[博士学位论文],南京;南京航空航天大学,2001
[33]熊洪允,曾绍标,毛云英,应用数学基础(第三版),天津:天津大学出版社,2003-07
[34]Kulik C,Vermandel M,Gibon D,Caudrelier J.M,Maouche, S,Rousseau J,Comparison of optimised treatment plans for radiosurgery and conformal radiotherapy,Engineering in Medicine and Biology Society, 2001,3:25-28, Proceedings of the 23rd Annual International Conference of the IEEE
[35]李佳,显像管玻壳及其模具 CAD/CAM 技术研究:[硕士学位论文],天津:天津大学,1990
[36]任忠宝,颅颌面整形手术方案可视化技术研究:[硕士学位论文],天津:天津大学,2005
[37]刘坤迪,李佳,黄田,缺损颅骨重构与 CAD 技术,CAD/CAM 与制造业信息化,2002,9
[38]杨芙清,面向对象的系统分析,北京:清华大学出版社,1998
[39]周峰,王洪玉,计算机软件技术基础,北京:化学工业出版社,2002,272-276
[40]蓝雯飞,C++面向对象编程是相同探讨,计算机工程与应用,2004,40(22):104-106
[41]王道平,冯振声,董 玉友,基于面向对象的专家系统设计方法研究,河北科技大学学报,1999,20(2):19-23
[42]王维江,面向对象方法的程序设计简述,航空计算技术,2004,34(2):48-50
[43]Ali Fauzi M,Du Weichang,Toward Reuse of Object-oriented Software Design Models,2004,46(8):499-517
[44]窦连旺,陈曦,刘鲁源,基于面向对象技术的参数化 CAD 系统,计算机工程,2004,30(9):182-185
[45]费佩燕,闫允一,郭宝龙,VC++中动态链接库的实现,现代电子技术,2003(8):9-11
[46]周长发,周建欣,Visual C++6.0 多媒体编程技术与实例,北京:电子工业出版社,1999
[2]本书编委会,Visual C++编程篇,北京:电子工业出版社,2005-05
[3]谭浩强,C 程序设计,北京:清华大学出版社,1997-08
[4]林锐, 韩永泉,高质量程序设计指南 C++/C 语言,北京:电子工业出版社,2005-05
[5]李佳,计算机辅助设计与制造,天津:天津大学出版社,2003-09
[6]Mastering CAD/CAM,Ibrahim Zeid Northeastern University. Singapore:McGRAW.HILL INTERNATIONAL EDITION,2005
[7]李佳,用于放射治疗的数字化射野适形铅模制作技术,国家发明专利申请号:200510013909.1
[8]卫炜,基于 ACIS 几何平台 CAD 系统开发与应用的初步实践: [硕士学位论文],南京;南京航空航天大学,2000
[9]王同胜,张连芳,王平,赵政,赵文钦,计算机技术及应用基础,天津:天津大学出版社,2004-04-01
[10]胡逸民,适形放疗——肿瘤放射物理学的新进展,实用肿瘤杂志,2000, 15(4):221-223
[11]邱学军,史荣,冯宁远,杨伟志,立体定向适形放疗的几个重要技术问题,中华肿瘤杂志,2000,22(5):420-421
[12]洪卫,适形放疗发展综述,实用癌症杂志,2003,18(4):439-440
[13]惠周光,殷蔚伯,二十一世纪的放射治疗——调强适形放疗,癌症进展,2003,1:14-19
[14]张水泉,石登正,曾达夫,调强适形放疗的技术和设备,现代医学仪器与应用,1999,44(4):12-13
[15]Mohan R, Barest G, Brewster LJ, et, A comprehensive three-dimensional radiation treatment planning system,Int J Radiat Oncol Biol Phys,1988,15(4):481-484
[16]胡逸民,谷铣之,适形放射治疗——肿瘤放射治疗新技术进展,肿瘤防治杂志,1998,5(4):243-245
[17]胡逸民,放射物理在肿瘤治疗中的地位与作用,中国肿瘤,1995,4(6):9-10
[18]王伟学,精确适形铅模系统的应用及改良,浙江医学,2004,26(10):759
[19]陈康,王捷,二维自动切割机制作肿瘤适形放疗档块在肿瘤放射治疗中的应用,医疗卫生装备,2004,8:54-55
[20]吴登梅,放疗适用于那些肿瘤,卫生与生活报,2004-05-03
[21]王闯,戴建荣,胡逸民,射野方向优化方法,中华放射肿瘤学杂志,2004,13(2):104-106
[22]Moore C.J.,Computerised conformal radiation therapy-a critical process,Computing & Control Engineering Journal,1995,6(5):205-210
[23]包尚联,用于肿瘤诊断和放疗的医学影像学研究,中国生物医学工程学会第六次会员代表大会学术会议论文摘要汇编,2004
[24]胡逸民,肿瘤靶向放射治疗——放射治疗的新方向,第一届中国肿瘤靶向治疗技术大会论文集,2003
[25]Jack J,3D Radiation therapy treatment planning: overview and assessment, Radiother Oncol,1999,13(2):331-336
[26]Purdy JA, Harms WB, Matthews J W, et al. Andvances in 3-D radiation treatment planning system: room-view display with real time interactivity,Int J Radiat Oncol Biol Phys,1993,27(7):933-935
[27]Bortfeld T,Schlegel W,Optimization of beam orientateon in radiateon therapy: some theoretical consideration,Phys Med Biol,1993,38: 291-304
[28]胡逸民,三维剂量计算模型和治疗计划方案优化,肿瘤放射物理学,北京:原子能出版社,1999
[29]Baudet V,Villard P.-F,Jaillet F,Beuve M,Shariat B,Towards accurate tumour tracking in lungs,Information Visualization,2003,IV 2003. Proceedings. Seventh International Conference on 16-18 July 2003 :338-343
[30]万凯,何援军,基于 ACIS 平台的大型三维 CAD 系统的设计与开发,计算机仿真,2004,10
[31]董洪伟,周儒荣,周来水,周弈,在 ACIS 平台上开发三维软件,计算机辅助工程,2002,4:
[32]安鲁陵,基于 ACIS 几何平台的 CAD/CAM 软件开发关键技术研究:[博士学位论文],南京;南京航空航天大学,2001
[33]熊洪允,曾绍标,毛云英,应用数学基础(第三版),天津:天津大学出版社,2003-07
[34]Kulik C,Vermandel M,Gibon D,Caudrelier J.M,Maouche, S,Rousseau J,Comparison of optimised treatment plans for radiosurgery and conformal radiotherapy,Engineering in Medicine and Biology Society, 2001,3:25-28, Proceedings of the 23rd Annual International Conference of the IEEE
[35]李佳,显像管玻壳及其模具 CAD/CAM 技术研究:[硕士学位论文],天津:天津大学,1990
[36]任忠宝,颅颌面整形手术方案可视化技术研究:[硕士学位论文],天津:天津大学,2005
[37]刘坤迪,李佳,黄田,缺损颅骨重构与 CAD 技术,CAD/CAM 与制造业信息化,2002,9
[38]杨芙清,面向对象的系统分析,北京:清华大学出版社,1998
[39]周峰,王洪玉,计算机软件技术基础,北京:化学工业出版社,2002,272-276
[40]蓝雯飞,C++面向对象编程是相同探讨,计算机工程与应用,2004,40(22):104-106
[41]王道平,冯振声,董 玉友,基于面向对象的专家系统设计方法研究,河北科技大学学报,1999,20(2):19-23
[42]王维江,面向对象方法的程序设计简述,航空计算技术,2004,34(2):48-50
[43]Ali Fauzi M,Du Weichang,Toward Reuse of Object-oriented Software Design Models,2004,46(8):499-517
[44]窦连旺,陈曦,刘鲁源,基于面向对象技术的参数化 CAD 系统,计算机工程,2004,30(9):182-185
[45]费佩燕,闫允一,郭宝龙,VC++中动态链接库的实现,现代电子技术,2003(8):9-11
[46]周长发,周建欣,Visual C++6.0 多媒体编程技术与实例,北京:电子工业出版社,1999
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