拟南芥活性氧应答基因的转录调控分子机制研究
摘要
在高等植物中,活性氧作为重要的信号分子介导了防御反应、程序性死亡、气孔关闭、细胞生长和植物发育调控等许多重要的生理过程。活性氧能够广泛地调控许多基因的表达,暗示了在植物细胞中存在复杂的活性氧应答的转录调控网络,但目前对于这一复杂调控网络中的许多细节仍不清楚。
本研究通过基因芯片技术在基因组水平上系统研究检测了ABA以及H202对拟南芥幼苗基因表达的调控。发现外源H202处理使459个基因的转录水平明显增加,同时使221个基因的表达显著减少,显示H202也是一种重要的转录调节物质,广泛地调控了许多基因的表达。而且ABA和H202对基因表达的调控存在相当大的重叠,它们可能通过一种协同模式调控下游基因的表达。通过生物信息学检索,本研究从活性氧特异应答基因的启动子序列中发现8个潜在的氧化胁迫应答的顺式作用元件。通过基因枪介导的瞬时表达系统检测发现4个保守序列元件在H202、MV等不同种类的活性氧处理下能够诱导下游萤光素酶基因的表达,它们可能作为氧化胁迫应答的元件(ROS responsive element)参与活性氧应答的转录调控。
在上述研究的基础上,发现AP2/EREBP家族转录因子ERF6能够特异地与ROE8结合,共转化ERF6能够显著增强ROE8的转录活性,而且H202处理能够促进ERF6对ROE8的激活效应。进一步的研究发现ERF6能够与MPK3／6发生直接的相互作用,MPK6能够磷酸化ERF6蛋白的Ser266和Ser269残基。ERF6磷酸化位点的突变会引起ERF6亚细胞定位的改变,ERF6DD定位于细胞核中,而非活化状态的ERF6AA主要存在于细胞质中。35S-ERF6WT、35S-ERF6DD超表达转基因植物在萌发和生长早期对H202更加敏感,一些活性氧应答基因的表达也明显增加。免疫共沉淀结果还显示H202和磷酸化能增加ERF6和MPK6复合体的积累。上述结果显示ERF6作为活性氧应答的转录因子,接受活性氧激活的MPK6的调控,介导了活性氧对于基因表达和幼苗生长发育的调控过程。
本研究工作系统比较分析了H202对基因表达的调控作用,通过生物信息学和遗传学分析检测了在活性氧应答基因启动子中存在的氧化胁迫应答元件,并鉴定了其中一个顺式作用元件ROE8的结合蛋白ERF6的功能,发现ROS-MPK6-ERF6途径部分地介导了活性氧对于基因表达的调控过程。这一研究为阐明活性氧应答的转录调控机制提供了重要的基因组学和遗传学线索。
Reactive oxygen species (ROS) has been characterized as an important signal molecule that mediates many developmental and physiological processes in plants, which include biotic and abiotic stress responses, stomotal movement, programmed cell death, growth and development. ROS also plays a global role in gene transcription. So far, details of the ROS responsive transcriptional network are still largely unknown.
To gain insight into the coordination of gene expression profiles under abscisic acid (ABA) and H2O2 applications, global changes in gene expression in response to ABA and H2O2 in Arabidopsis seedlings were investigated by microarray analysis.459 transcripts were found to be significantly increased, whereas another 221 decreased following H2O2 treatment compared with control. These results suggest the global role of H2O2 in gene transcription. The transcriptional responses induced by the application of exogenous ABA and H2O2 overlapped substantially. Promoters of ROS up-regulated genes were selected for a bioinformatics search to identify the potential transcription factor binding sites responsible for ROS induced gene expression, and four of eight potential ROS responsive cis-elements (ROEs) are sufficient to confer a rapid increase of luciferase under H2O2 and MV treatment indicated their roles in ROS responsive gene transcription.
We also found that an AP2/EREBP transcription factor ERF6 could bind to the ROE8 specially. Co-expression of ERF6 effector enhanced the expression of ROE8 driver luciferase gene, we also found that ERF6 interacted physically with MPK6 in vitro and in vivo, and also served as a substrate of MPK6. Two Ser residues, Ser 266 and Ser 269 were the putative phosphorylation site of ERF6. After application of H2O2, phosphorylation by MPK6, ERF6 relocalizes from cytoplasm to the nucleus. Expression of ROS responsive genes is strongly up-regulated in 35S-ERF6WT and 35S-ERF6DD transgenic plants. Furthermore, growths of 35S-ERF6WT and 35S-ERF6DD seedlings are more sensitive to H2O2 treatment than WT or 35S-ERF6AA transgenic plants. Immunoprecipitation results indicated that H2O2 treatment and SS to DD mutation also increased the stability of ERF6-MPK6 complex. Based on those results, the MPK6-ERF6 pathway has established that it mediated the ROS responsive transcription and seedling growth regulation.
In this work, H2O2 responsive gene transcription was compared at genomic ranges and potential ROS responsive cis-elements were identified. The function of ROE8 binding protein ERF6 in controlling the ROS responsive gene expression was also characterized. We found that H2O2 responsive gene expression partly dependent on ROS-MPK6-ERF6 pathway. These data may provide new insight into ROS responsive gene regulation mechanism.
本研究通过基因芯片技术在基因组水平上系统研究检测了ABA以及H202对拟南芥幼苗基因表达的调控。发现外源H202处理使459个基因的转录水平明显增加,同时使221个基因的表达显著减少,显示H202也是一种重要的转录调节物质,广泛地调控了许多基因的表达。而且ABA和H202对基因表达的调控存在相当大的重叠,它们可能通过一种协同模式调控下游基因的表达。通过生物信息学检索,本研究从活性氧特异应答基因的启动子序列中发现8个潜在的氧化胁迫应答的顺式作用元件。通过基因枪介导的瞬时表达系统检测发现4个保守序列元件在H202、MV等不同种类的活性氧处理下能够诱导下游萤光素酶基因的表达,它们可能作为氧化胁迫应答的元件(ROS responsive element)参与活性氧应答的转录调控。
在上述研究的基础上,发现AP2/EREBP家族转录因子ERF6能够特异地与ROE8结合,共转化ERF6能够显著增强ROE8的转录活性,而且H202处理能够促进ERF6对ROE8的激活效应。进一步的研究发现ERF6能够与MPK3／6发生直接的相互作用,MPK6能够磷酸化ERF6蛋白的Ser266和Ser269残基。ERF6磷酸化位点的突变会引起ERF6亚细胞定位的改变,ERF6DD定位于细胞核中,而非活化状态的ERF6AA主要存在于细胞质中。35S-ERF6WT、35S-ERF6DD超表达转基因植物在萌发和生长早期对H202更加敏感,一些活性氧应答基因的表达也明显增加。免疫共沉淀结果还显示H202和磷酸化能增加ERF6和MPK6复合体的积累。上述结果显示ERF6作为活性氧应答的转录因子,接受活性氧激活的MPK6的调控,介导了活性氧对于基因表达和幼苗生长发育的调控过程。
本研究工作系统比较分析了H202对基因表达的调控作用,通过生物信息学和遗传学分析检测了在活性氧应答基因启动子中存在的氧化胁迫应答元件,并鉴定了其中一个顺式作用元件ROE8的结合蛋白ERF6的功能,发现ROS-MPK6-ERF6途径部分地介导了活性氧对于基因表达的调控过程。这一研究为阐明活性氧应答的转录调控机制提供了重要的基因组学和遗传学线索。
Reactive oxygen species (ROS) has been characterized as an important signal molecule that mediates many developmental and physiological processes in plants, which include biotic and abiotic stress responses, stomotal movement, programmed cell death, growth and development. ROS also plays a global role in gene transcription. So far, details of the ROS responsive transcriptional network are still largely unknown.
To gain insight into the coordination of gene expression profiles under abscisic acid (ABA) and H2O2 applications, global changes in gene expression in response to ABA and H2O2 in Arabidopsis seedlings were investigated by microarray analysis.459 transcripts were found to be significantly increased, whereas another 221 decreased following H2O2 treatment compared with control. These results suggest the global role of H2O2 in gene transcription. The transcriptional responses induced by the application of exogenous ABA and H2O2 overlapped substantially. Promoters of ROS up-regulated genes were selected for a bioinformatics search to identify the potential transcription factor binding sites responsible for ROS induced gene expression, and four of eight potential ROS responsive cis-elements (ROEs) are sufficient to confer a rapid increase of luciferase under H2O2 and MV treatment indicated their roles in ROS responsive gene transcription.
We also found that an AP2/EREBP transcription factor ERF6 could bind to the ROE8 specially. Co-expression of ERF6 effector enhanced the expression of ROE8 driver luciferase gene, we also found that ERF6 interacted physically with MPK6 in vitro and in vivo, and also served as a substrate of MPK6. Two Ser residues, Ser 266 and Ser 269 were the putative phosphorylation site of ERF6. After application of H2O2, phosphorylation by MPK6, ERF6 relocalizes from cytoplasm to the nucleus. Expression of ROS responsive genes is strongly up-regulated in 35S-ERF6WT and 35S-ERF6DD transgenic plants. Furthermore, growths of 35S-ERF6WT and 35S-ERF6DD seedlings are more sensitive to H2O2 treatment than WT or 35S-ERF6AA transgenic plants. Immunoprecipitation results indicated that H2O2 treatment and SS to DD mutation also increased the stability of ERF6-MPK6 complex. Based on those results, the MPK6-ERF6 pathway has established that it mediated the ROS responsive transcription and seedling growth regulation.
In this work, H2O2 responsive gene transcription was compared at genomic ranges and potential ROS responsive cis-elements were identified. The function of ROE8 binding protein ERF6 in controlling the ROS responsive gene expression was also characterized. We found that H2O2 responsive gene expression partly dependent on ROS-MPK6-ERF6 pathway. These data may provide new insight into ROS responsive gene regulation mechanism.
引文
王鹏程,杜艳艳,宋纯鹏。(2009)植物细胞一氧化氮信号转导研究进展。植物学报44,517-525
Abe, H., Yamaguchi-Shinozaki, K., Urao, T., lwasaki, T., Hosokawa, D., and Shinozaki, K. (1997). Role of Arabidopsis MYC and MYB homologs in drought-and abscisic acid-regulated gene expression. Plant Cell 9,1859-1868.
Achard, P., Renou, J.-P., Berthom, R., Harberd, N.P., and Genschik, P. (2008). Plant DELLAs restrain growth and promote survival of adversity by reducing the levels of reactive oxygen Species. Curr Biol 18,656-660.
Agarwal, P., Agarwal, P., Nair, S., Sopory, S., and Reddy, M. (2007), Stress-inducible DREB2A transcription factor from Pennisetum glaucum is a phosphoprotein and its phosphorylation negatively regulates its DNA-binding activity. Mol Genet Genomics 277,189-198.
Ahlfors, R., Macioszek, V., Rudd, J., Brosche, M., Schlichting, R., Scheel, D., and Kangasjarvi, J. (2004). Stress hormone-independent activation and nuclear translocation of mitogen-activated protein kinases in Arabidopsis thaliana during ozone exposure. Plant J 40,512-522.
Andreasson, E., Jenkins, T., Brodersen, P., Thorgrimsen, S., Petersen, N.H., Zhu, S., Qiu, J.L., Micheelsen, P., Rocher, A., Petersen, M., et al. (2005). The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO J 24,2579-2589.
Angelini, R., Tisi, A., Rea, G., Chen, M.M., Botta, M., Federico, R., and Cona, A. (2008). Involvement of polyamine oxidase in wound healing. Plant Physiol 146,162-177.
Apel, K., and Hirt, H. (2004). Reactive oxygen species:metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol 55,373-399.
Arenas-Huertero, F., Arroyo, A., Zhou, L., Sheen, J., and Leon, P. (2000). Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar. Genes Dev 14,2085-2096.
Asai, T., Tena, G., Plotnikova, J., Willmann, M.R., Chiu, W.-L., Gomez-Gomez, L., Boller, T., Ausubel, F.M., and Sheen, J. (2002). MAP kinase signalling cascade in Arabidopsis innate immunity. Nature 415,977-983.
Aslund, F., Zheng, M., Beckwith, J., and Storz, G. (1999). Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status. Proc Natl Acad Sci 96,6161-6165.
Assmann, S.M. (2003). OPEN STOMATA1 opens the door to ABA signaling in Arabidopsis guard cells. Trends Plant Sci 8, 151-153.
Bailey, T.L., and Elkan, C. (1994). Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 2,28-36.
Bardwell, L. (2006). Mechanisms of MAPK signalling specificity. In Biochemical Society Transactions, pp.837-841.
Baxter-Burrell, A., Yang, Z., Springer, P.S., and Bailey-Serres, J. (2002). RopGAP4-Dependent Rop GTPase rheostat control of Arabidopsis oxygen deprivation tolerance. Science 296,2026-2028.
Belles-Boix, E., Babiychuk, E., Van Montagu, M., Inz, D., and Kushnir, S. (2000). CEO1, a new protein from Arabidopsis thaliana, protects yeast against oxidative damage. FEBS Lett 482,19-24.
Berrin, J.-G, Pierrugues, O., Brutesco, C., Alonso, B., Montillet, J.-L., Roby, D., and Kazmaier, M. (2005). Stress induces the expression of AtNADK-1, a gene encoding a NAD(H) kinase in Arabidopsis thaliana. Mol Genet Genomics 273,10-19.
Bethke, G., Unthan, T., Uhrig, J.F., Poschl, Y., Gust, A. A., Scheel, D., and Lee, J. (2009). Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signaling. Proc Natl Acad Sci 106, 8067-8072.
Bozonet, S.M., Findlay, V.J., Day, A.M., Cameron, J., Veal, E.A., and Morgan, B.A. (2005). Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide. J Biol Chem 280,23319-23327.
Bright, J., Desikan, R., Hancock, J.T., Weir, I.S., and Neill, S.J. (2006). ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis. Plant J 45,113-122.
Brown, R.L., Kazan, K., McGrath, K.C., Maclean, D.J., and Manners, J.M. (2003). A role for the GCC-Box in jasmonate-mediated activation of the PDF1.2 gene of Arabidopsis. Plant Physiol 132,1020-1032.
Buck, V., Quinn, J., Pino, T.S., Martin, H., Saldanha, J., Makino, K., Morgan, B.A., and Millar, J.B.A. (2001). Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway. Mol Biol Cell 12,407-419.
Bulyk, M.L. (2006). DNA microarray technologies for measuring protein-DNA interactions. Curr Opin Biotec 17,422-430.
Buttner, M., and Singh, K.B. (1997). Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein. Proc Natl Acad Sci 94, 5961-5966.
Camilla, H., Paul, E.G., Silje, H.N., Tage, T., Marte, K.V., Vigdis, N., and Reidunn, B.A. (2003). ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress. Plant Mol Biol V53,313-326.
Cao, H., Bowling, S.A., Gordon, A.S., and Dong, X. (1994). Characterization of an Arabidopsis mutant that is nonresponsive to inducers of systemic acquired resistance. Plant Cell 6,1583-1592.
Cao, Y., Li, Z., Chen, T., Zhang, Z., Zhang, J., and Chen, S. (2008). Overexpression of a tobacco small G protein gene NtRopl causes salt sensitivity and hydrogen peroxide production in transgenic plants. Sci China Ser C Life Sci 51,383-390.
Casolo, V., Petrussa, E., Krajnakova, J., Macri, F., and Vianello, A. (2005). Involvement of the mitochondrial K(+)ATP channel in H2O2- or NO-induced programmed death of soybean suspension cell cultures. J Exp Bot 56,997-1006.
Chen, C., and Chen, Z. (2000). Isolation and characterization of two pathogen- and salicylic acid-induced genes encoding WRKY DNA-binding proteins from tobacco. Plant Mol Biol 42,387-396.
Chen, Y.-L., Huang, R., Xiao, Y.-M., Lu, P., Chen, J., and Wang, X.-C. (2004). Extracellular calmodulin-induced stomatal closure is mediated by heterotrimeric G protein and H2O2. Plant Physiol 136,4096-4103.
Chen, Z., Silva, H., and Klessig, D.F. (1993). Active oxygen species in the induction of plant systemic acquired resistance by salicylic acid. Science 262,1883-1886.
Cheng, C., Yun, K.-Y, Ressom, H., Mohanty, B., Bajic, V, Jia, Y, Yun, S., and de los Reyes, B. (2007). An early response regulatory cluster induced by low temperature and hydrogen peroxide in seedlings of chilling-tolerant japonica rice. BMC Genomics 8,175.
Cheng, Y., and Song, C. (2006). Hydrogen peroxide homeostasis and signaling in plant cells. Sci China C Life Sci 49,1-11.
Cheong, Y.H., Moon, B.C., Kim, J.K., Kim, C.Y, Kim, M.C., Kim, I.H., Park, C.Y., Kim, J.C., Park, B.O., Koo, S.C., et al. (2003). BWMK1, a rice mitogen-activated protein kinase, locates in the nucleus and mediates pathogenesis-related gene expression by activation of a transcription factor. Plant Physiol 132,1961-1972.
Ciftci-Yilmaz, S., Morsy, M.R., Song, L., Coutu, A., Krizek, B.A., Lewis, M.W., Warren, D., Cushman, J., Connolly, E.L., and Mittler, R. (2007). The EAR-motif of the Cys2/His2-type zinc finger protein ZAT7 plays a key role in the defense response of Arabidopsis to salinity stress. J Biol Chem 282,9260-9268.
Clark, D., Durner, J., Navarre, D.A., and Klessig, D.F. (2000). Nitric oxide inhibition of tobacco catalase and ascorbate peroxidase. . Mol Plant-Microbe Interact 13,1380-1384.
Clarke, A., Desikan, R., Hurst, R.D., Hancock, J.T., and Neill, S.J. (2000). NO way back:nitric oxide and programmed cell death in Arabidopsis thaliana suspension cultures. Plant J 24,667-677.
Coego, A., Ramirez, V, Ellul, P., Mayda, E., and Vera, P. (2005a). The H2O2-regulated Ep5C gene encodes a peroxidase required for bacterial speck susceptibility in tomato. Plant J 42,283-293.
Coego, A., Ramirez, V., Gil, M.J., Flors, V., Mauch-Mani, B., and Vera, P. (2005b). An Arabidopsis homeodomain transcription factor, OVEREXPRESSOR OF CATIONIC PEROXIDASE 3, mediates resistance to infection by necrotrophic pathogens. Plant Cell 17,2123-2137.
Coelho, S.M., Taylor, A.R., Ryan, K.P., Sousa-Pinto, I., Brown, M.T., and Brownlee, C. (2002). Spatiotemporal patterning of reactive oxygen production and Ca2+ wave propagation in Fucus Rhizoid Cells. Plant Cell 14,2369-2381.
Cona, A., Cenci, F., Cervelli, M., Federico, R., Mariottini, P., Moreno, S., and Angelini, R. (2003). Polyamine oxidase, a hydrogen peroxide-producing enzyme, is up-regulated by light and down-regulated by auxin in the outer tissues of the maize mesocotyl. Plant Physiol 131,803-813.
Crooks, G.E., Hon, G., Chandonia, J.-M., and Brenner, S.E. (2004). WebLogo:A Sequence Logo Generator. Genome Res 14, 1188-1190.
Diaz, M., Achkor, H., Titarenko, E., and Martinez, M.C. (2003). The gene encoding glutathione- dependent formaldehyde dehydrogenase/GSNO reductase is responsive to wounding, jasmonic acid and salicylic acid. FEBS Lett 543,136-139.
Doczi, R., Brader, G., Pettko-Szandtner, A., Rajh,I., Djamei, A., Pitzschke, A., Teige, M., and Hirt, H. (2007). The arabidopsis mitogen-activated protein kinase kinase mkk3 is upstream of group c mitogen-activated protein kinases and participates in pathogen signaling. Plant Cell 19,3266-3279.
Dejardin, A., Sokolov, L.N., and Kleczkowski, L.A. (1999). Sugar/osmoticum levels modulate differential abscisic acid-independent expression of two stress-responsive sucrose synthase genes in Arabidopsis:Biochem J 344,503-509.
Danon, A., Miersch, O., Felix, G., Camp, R.G.L., and Apel, K. (2005). Concurrent activation of cell death-regulating signaling pathways by singlet oxygen in Arabidopsis thaliana. Plant J 41,68-80.
Davletova, S., Rizhsky, L., Liang, H., Shengqiang, Z., Oliver, D.J., Coutu, J., Shulaev, V, Schlauch, K., and Mittler, R. (2005a). Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis. Plant Cell 17, 268-281.
Davletova, S., Schlauch, K., Coutu, J., and Mittler, R. (2005b). The zinc-finger protein Zatl2 plays a central role in reactive oxygen and abiotic stress signaling in Arabidopsis. Plant Physiol 139,847-856.
De Tullio, M.C., Jiang, K., and Feldman, L.J. (2010). Redox regulation of root apical meristem organization:Connecting root development to its environment. Plant Physiol Biochem In Press, Corrected Proof.
Degols, G., Shiozaki, K., and Russell, P. (1996). Activation and regulation of the Spcl stress-activated protein kinase in Schizosaccharomyces pombe. Mol Cell Biol 16,2870-2877.
Degterev, A., and Yuan, J. (2008). Expansion and evolution of cell death programmes. Nat Rev Mol Cell Biol 9,378-390.
del Rio, L.A., Corpas, F.J., Sandalio, L.M., Palma, J.M., Gomez, M., and Barroso, J.B. (2002). Reactive oxygen species, antioxidant systems and nitric oxide in peroxisomes. J Exp Bot 53,1255-1272.
Delaunay, A., Pflieger, D., Barrault, M.-B., Vinh, J., and Toledano, M.B. (2002). A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation. Cell Ⅲ,471-481.
Desikan, R., A.-H.-Mackerness, S., Hancock, J.T., and Neill, S.J. (2001). Regulation of the Arabidopsis Transcriptome by Oxidative Stress. Plant Physiol 127,159-172.
Desikan, R., Griffiths, R., Hancock, J., and Neill, S. (2002). A new role for an old enzyme:Nitrate reductase-mediated nitric oxide generation is required for abscisic acid-induced stomatal closure in Arabidopsis thaliana. Proc Natl Acad Sci 99,16314-16318.
Desikan, R., Hancock, J.T., Bright, J., Harrison, J., Weir, I., Hooley, R., and Neill, S.J. (2005). A Role for ETR1 in hydrogen peroxide signaling in stomatal guard cells. Plant Physiol 137,831-834.
Desikan, R., Neill, S.J., and Hancock, J.T. (2000). Hydrogen peroxide-induced gene expression in Arabidopsis thaliana. Free Radical Biol Med 28,773-778.
Desikan, R., Reynolds, A., Hancock, J.T., and Neill, S.J. (1998). Harpin and hydrogen peroxide both initiate programmed cell death but have differential effects on defence gene expression in Arabidopsis suspension cultures. Biochem J 330,115-120.
Despres, C., Chubak, C., Rochon, A., Clark, R., Bethune, T., Desveaux, D., and Fobert, P.R. (2003). The Arabidopsis NPR1 disease resistance protein is a novel cofactor that confers redox regulation of DNA binding activity to the basic domain/leucine zipper transcription factor TGA1. Plant Cell 15,2181-2191.
Despres, C., DeLong, C., Glaze, S., Liu, E., and Fobert, P.R. (2000). The Arabidopsis NPR1/NIMI protein enhances the dna binding activity of a subgroup of the TGA family of bZIP transcription tactors. Plant Cell 12,279-290.
Ding, H., Hidalgo, E., and Demple, B. (1996). The redox state of the [2Fe-2S] clusters in SoxR protein regulates its activity as a transcription factor. J Biol Chem 271,33173-33175.
Djamei, A., Pitzschke, A., Nakagami, H., Rajh, I., and Hirt, H. (2007). Trojan horse strategy in Agrobacterium transformation: abusing MAPK defense signaling. Science 318,453-456.
Dong, X. (2004). NPR1, all things considered. Curr Opin Plant Biol 7,547-552.
Du, Y.-Y., Wang, P.-C., Chen, J., and Song, C.-P. (2008). Comprehensive functional analysis of the catalase gene family in Arabidopsis thaliana. J Integrat Plant Biol 50,1318-1326.
Eshdat, Y., Holland, D., Faltin, Z., and Ben-Hayyim, G. (1997). Plant glutathione peroxidases. Physiol Plant 100,234-240.
Etienne, P., Petitot, A.-S., Houot, V., Blein, J.-P., and Suty, L. (2000). Induction of TCI 7, a gene encoding a β-subunit of proteasome, in tobacco plants treated with elicitins, salicylic acid or hydrogen peroxide. FEBS Lett 466,213-218.
Eulgem, T., Rushton, P.J., Schmelzer, E., Hahlbrock, K., and Somssich, I.E. (1999). Early nuclear events in plant defence signalling: rapid gene activation by WRKY transcription factors. EMBO J 18,4689-4699.
Eulgem, T., and Somssich, I.E. (2007). Networks of WRKY transcription factors in defense signaling. Curr Opin Plant Biol 10, 366-371.
Falk, A., Feys, B.J., Frost, L.N., Jones, J.D.G., Daniels, M.J., and Parker, J.E. (1999). EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases. Proc Natl Acad Sci 96,3292-3297.
Feilner, T., Hultschig, C., Lee,J., Meyer, S., Immink, R.G.H., Koenig, A., Possling, A., Seitz, H., Beveridge, A., Scheel, D., etal. (2005). High throughput identification of potential Arabidopsis mitogen-activated protein kinases substrates. Mol Cell Proteomics 4,1558-1568.
Fiil, B.K., Petersen, K., Petersen, M., and Mundy, J. (2009). Gene regulation by MAP kinase cascades. Curr Opin Plant Biol 12, 615-621.
Finkelstein, R.R., Gampala, S.S.L., and Rock, C.D. (2002). Abscisic acid signaling in seeds and seedlings. Plant Cell 14, S15-S45.
Fobert, P.R., and Despres, C. (2005). Redox control of systemic acquired resistance. Curr Opin Plant Biol 8,378-382.
Foreman, J., Demidchik, V, Bothwell, J.H.F., Mylona, P., Miedema, H., Torres, M.A., Linstead, P., Costa, S., Brownlee, C., Jones, J.D.G., et al. (2003). Reactive oxygen species produced by NADPH oxidase regulate plant cell growth. Nature 422,442-446.
Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, H., Hamann, T., Offringa, R., and Jurgens, G. (2003). Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis. Nature 426,147-153.
Fryer, M.J., Oxborough, K., Mullineaux, P.M., and Baker, N.R. (2002). Imaging of photo-oxidative stress responses in leaves. J Exp Bot 53,1249-1254.
Fuangthong, M., Atichartpongkul, S., Mongkolsuk, S., and Helmann, J.D. (2001). OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis. J Bacteriol 183,4134-4141.
Fujii, H., Chinnusamy, V., Rodrigues, A., Rubio, S., Antoni, R., Park, S.-Y, Cutler, S.R., Sheen, J., Rodriguez, P.L., and Zhu, J.-K. (2009). In vitro reconstitution of an abscisic acid signalling pathway. Nature 462,660-664.
Fujimoto, S.Y., Ohta, M., Usui, A., Shinshi, H., and Ohme-Takagi, M. (2000). Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Plant Cell 12,393-404.
Fujioka, S., Niu, J., Schmidt, C., Sclabas, G.M., Peng, B., Uwagawa, T., Li, Z., Evans, D.B., Abbruzzese, J.L., and Chiao, P.J. (2004). NF-κB and AP-1 connection:mechanism of NF-KB-Dependent regulation of AP-1 activity. Mol Cell Biol 24,7806-7819.
Gadjev, I., Vanderauwera, S., Gechev, T.S., Laloi, C., Minkov, I.N., Shulaev, V., Apel, K., lnze, D., Mittler, R., and Van Breusegem, F. (2006). Transcriptomic footprints disclose specificity of reactive oxygen species signaling in Arabidopsis. Plant Physiol 141, 436-445.
Gechev, T., Gadjev, I., Van Breusegem, F., Inze, D., Dukiandjiev, S., Toneva, V, and Minkov, I. (2002). Hydrogen peroxide protects tobacco from oxidative stress by inducing a set of antioxidant enzymes. Cell Mol Life Sci 59,708-714.
Gechev, T.S., Breusegem, F.V., Stone, J.M., Denev, I., and Laloi, C. (2006). Reactive oxygen species as signals that modulate plant stress responses and programmed cell death. BioEssays 28,1091-1101.
Gechev, T.S., and Hille, J. (2005). Hydrogen peroxide as a signal controlling plant programmed cell death. J Cell Biol 168,17-20.
Geiger, D., Scherzer, S., Mumm, P., Stange, A., Marten, I., Bauer, H., Ache, P., Matschi, S., Liese, A., Al-Rasheid, K.A.S., et al. (2009). Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair. Proc Natl Acad Sci 106,21425-21430.
Gelli, A., and Blumwald, E. (1997). Hyperpolarization-activated Ca2+-permeable channels in the plasma membrane of tomato cells. J Membrane Biol 155,35-45.
Geum, D., Son, G.H., and Kim, K. (2002). Phosphorylation-dependent cellular localization and thermoprotective role of heat shock protein 25 in Hippocampal Progenitor Cells. J Biol Chem 277,19913-19921.
Gibson, S.I. (2005). Control of plant development and gene expression by sugar signaling. Curr Opin Plant Biol 8,93-102.
Giraud, E., Ho, L.H.M., Clifton, R., Carroll, A., Estavillo, G., Tan, Y.-F., Howell, K.A., Ivanova, A., Pogson, B.J., Millar, A.H., et al. (2008). The absence of ALTERNATIVE OXIDASE1 a in Arabidopsis results in acute sensitivity to combined light and drought stress. Plant Physiol 147,595-610.
Goujon, T., Minic, Z., Amrani, A.E., Lerouxel, O., Aletti, E., Lapierre, C., Joseleau, J.-P., and Jouanin, L. (2003). AtBXL1 a novel higher plant (Arabidopsis thaliana) putative beta-xylosidase gene, is involved in secondary cell wall metabolism and plant development. Plant J 33,677-690.
Green, P.J., Kay, S.A., and Chua,N.H. (1987). Sequence-specific interactions of a pea nuclear factor with light-responsive elements upstream of the rbcS-3A gene. EMBO J 6,2543-2549.
Guan, L.M., Zhao, J., and Scandalios, J.G. (2000). Cis-elements and trans-factors that regulate expression of the maize Catl antioxidant gene in response to ABA and osmotic stress:H2O2 is the likely intermediary signaling molecule for the response. Plant J 22,87-95.
Gudesblat, G.E., Iusem, N.D., and Morris, P.C. (2007). Guard cell-specific inhibition of Arabidopsis MPK3 expression causes abnormal stomatal responses to abscisic acid and hydrogen peroxide. New Phytol 173,713-721.
Guiltinan, M., Marcotte, W., Jr, and Quatrano, R. (1990). A plant leucine zipper protein that recognizes an abscisic acid response element. Science 250,267-271.
Gutierrez, R., Lejay, L., Dean, A., Chiaromonte, F., Shasha, D., and Coruzzi, G. (2007). Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis. Genome Biol 8, R7.
Haake, V, Cook, D., Riechmann, J.L., Pineda, O., Thomashow, M.F., and Zhang, J.Z. (2002). Transcription factor CBF4 is a regulator of drought adaptation in Arabidopsis. Plant Physiol 130,639-648.
Hamilton, D.W.A., Hills, A., Kohler, B., and Blatt, M.R. (2000). Ca2+ channels at the plasma membrane of stomatal guard cells are activated by hyperpolarization and abscisic acid. Proc Natl Acad Sci 97,4967-4972.
Hancock, J.T., Henson, D., Nyirenda, M., Desikan, R., Harrison, J., Lewis, M., Hughes, J., and Neill, S.J. (2005). Proteomic identification of glvceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis. Plant Physiol Biochem 43,828-835.
Harding, S.A., Oh, S.H., and Roberts, D.M. (1997). Transgenic tobacco expressing a foreign calmodulin gene shows an enhanced production of active oxygen species. EMBO J 16,1137-1144.
Hattori, T., Totsuka, M., Hobo, T., Kagaya, Y., and Yamamoto-Toyoda, A. (2002). Experimentally determined sequence requirement of ACGT-containing abscisic acid response element. Plant Cell Physiol 43,136-140.
He, J.-X., Gendron, J.M., Sun, Y., Gampala, S.S.L., Gendron, N., Sun, C.Q., and Wang, Z.-Y. (2005a). BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses. Science 307,1634-1638.
He, J., Xu, H., She, X., Song, X., and Zhao, W. (2005b). The role and the interrelationship of hydrogen peroxide and nitric oxide in the UV-B-induced stomatal closure in broad bean. Funct Plant Biol 32,237-247.
He, R., Drury, GE., Rotari, V.I., Gordon, A., Willer, M., Farzaneh, T., Woltering, E.J., and Gallois, P. (2008). Metacaspase-8 modulates programmed cell death induced by ultraviolet light and H2O2 in Arabidopsis. J Biol Chem 283,774-783.
Herbig, A.F., and Helmann, J.D. (2001). Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA. Mol Microbiol 41,849-859.
Hicks, L.M., Cahoon, R.E., Bonner, E.R., Rivard, R.S., Sheffield, J., and Jez, J.M. (2007). Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thaliana. Plant Cell 19,2653-2661.
Hidalgo, E., and Demple, B. (1994). An iron-sulfur center essential for transcriptional activation by the redox-sensing SoxR protein. EMBO J 13,138-146.
Hideg, E., Barta, C., Kalai, T., Vass,I., Hideg, K., and Asada, K. (2002). Detection of singlet oxygen and superoxide with fluorescent sensors in leaves under stress by photoinhibition or UV radiation. Plant Cell Physiol 43,1154-1164.
Hideg, E., Kalai, T., Hideg, K., and Vass,I. (1998). Photoinhibition of photosynthesis in vivo results in singlet oxygen production detection via nitroxide-induced fluorescence quenching in broad bean leaves. Biochem 37,11405-11411.
Higo, K., and Higo, H. (1996). Cloning and characterization of the rice CatA catalase gene, a homologue of the maize Cat3 gene. Plant Mol Biol 30,505-521.
Himmelbach, A., Iten, M., and Grill, E. (1998). Signalling of abscisic acid to regulate plant growth. Philos T R Soc B:Biol Sci 353, 1439-1444.
Himmelbach, A., Yang, Y., and Grill, E. (2003). Relay and control of abscisic acid signaling. Curr Opin Plant Biol 6,470-479.
Hobo, T., Asada, M., Kowyama, Y, and Hattori, T. (1999). ACGT-containing abscisic acid response element (ABRE) and coupling element 3 (CE3) are functionally equivalent. Plant J 19,679-689.
Hong, Z., Jing, W., Utah, N., Randy, D.A., and Howard, M.G. (1997). Cloning and expression of an Arabidopsis gene encoding a putative peroxisomal ascorbate peroxidase. Plant Mol Biol 34,967-971.
Hord, C.L.H., Sun, Y.-J., Pillitteri, L.J., Torii, K.U., Wang, H., Zhang, S., and Ma, H, (2008). Regulation of Arabidopsis early anther development by the mitogen-activated protein kinases, MPK3 and MPK6, and the ERECTA and related receptor-like kinases. Mol Plant 1,645-658.
Hoth, S., Morgante, M., Sanchez, J.-P., Hanafey, M.K., Tingey, S.V., and Chua, N.-H. (2002). Genome-wide gene expression profiling in Arabidopsis thaliana reveals new targets of abscisic acid and largely impaired gene regulation in the abil-I mutant. J Cell Sci 115,4891-4900.
Huang, J., Sun, S.-J., Xu, D.-Q., Yang, X., Bao, Y.-M., Wang, Z.-F., Tang, H.-J., and Zhang, H. (2009a). Increased tolerance of rice to cold, drought and oxidative stresses mediated by the overexpression of a gene that encodes the zinc finger protein ZFP245. Biochem Biophys Res Commun 389,556-561.
Huang, X.-Y., Chao, D.-Y, Gao, J.-P., Zhu, M.-Z., Shi, M., and Lin, H.-X. (2009b). A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control. Genes Dev 23,1805-1817.
Ichimura, K., Casais, C., Peck, S.C., Shinozaki, K., and Shirasu, K. (2006). MEKK1 is required for MPK4 activation and regulates tissue-specific and temperature-dependent cell death in Arabidopsis. J Biol Chem 281,36969-36976.
Ikner, A., and Shiozaki, K. (2005). Yeast signaling pathways in the oxidative stress response. Mutat Res 569,13-27.
Imsande, J. (1999). Iron-sulfur clusters:Formation, perturbation, and physiological functions. Plant Physiol Biochem 37,87-97.
Islam, M.M., Munemasa, S., Hossain, M.A., Nakamura, Y, Mori, I.C., and Murata, Y. (2010). Roles of AtTPC1, vacuolar two pore channel 1, in Arabidopsis Stomatal Closure. Plant Cell Physiol 51,302-311.
Jammes, F., Song, C., Shin, D., Munemasa, S., Takeda, K., Gu, D., Cho, D., Lee, S., Giordo, R., Sritubtim, S., et al. (2009). MAP kinases MPK9 and MPK12 are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling. Proc Natl Acad Sci 106,20520-20525.
Jang, H.H., Lee, K.O., Chi, Y.H., Jung, B.G, Park, S.K., Park, J.H., Lee, J.R., Lee, S.S., Moon, J.C., and Yun, J.W. (2004). Two enzymes in one:two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function. Cell 117,625-635.
Jiang, Y, and Deyholos, M. (2009). Functional characterization of Arabidopsis NaCl-inducible WRKY25 and WRKY33 transcription factors in abiotic stresses. Plant Mol Biol 69,91-105.
Jin, H., Cominelli, E., Bailey, P., Parr, A., Mehrtens, F., Jones, J., Tonelli, C., Weisshaar, B., and Martin, C. (2000). Transcriptional repression by AtMYB4 controls production of UV-protecting sunscreens in Arabidopsis. EMBO J 19,6150-6161.
Jones, M.A., Raymond, M.J., Yang, Z., and Smirnoff, N. (2007). NADPH oxidase-dependent reactive oxygen species formation required for root hair growth depends on ROP GTPase. J Exp Bot 58,1261-1270.
Joo, J.H., Wang, S., Chen, J.G., Jones, A.M., and Fedoroff, N.V. (2005). Different signaling and cell death roles of heterotrimeric G Protein α and βsubunits in the Arabidopsis oxidative stress response to ozone. Plant Cell 17,957-970.
Kaffarnik, F., Muller, P., Leibundgut, M., Kahmann, R., and Feldbrugge, M. (2003). PKA and MAPK phosphorylation of Prfl allows promoter discrimination in Ustilago maydis. EMBO J 22,5817-5826.
Katiyar-Agarwal, S., Zhu, J., Kim, K., Agarwal, M., Fu, X., Huang, A., and Zhu, J.-K. (2006). Colloquium Paper:The plasma membrane Na+/H+ antiporter SOS1 interacts with RCD1 and functions in oxidative stress tolerance in Arabidopsis. Proc Natl Acad Sci 103,18816-18821.
Keller, T., Damude, H.G., Werner, D., Doerner, P., Dixon, R.A., and Lamb, C. (1998). A plant homolog of the neutrophil NADPH oxidase gp91phox subunit gene encodes a plasma membrane protein with Ca2+ binding motifs. Plant Cell 10,255-266.
Kenichi, H., and Hiromi, H. (1996). Cloning and characterization of the rice CatA catalase gene, a homologue of the maize Cat3 gene. Plant Mol Biol 30,505-521.
Kimura, M., Manabe, K., Abe, T., Yoshida, S., Matsui, M., and Yamamoto, Y.Y. (2003). Analysis of hydrogen peroxide-independent expression of the high-light-inducible ELIP2 Gene with the aid of the ELIP2 promoter-luciferase fusion. Photochem Photobiol 77,668-674.
Klusener, B., Young, J.J., Murata, Y., Allen, G.J., Mori, I.C., Hugouvieux, V., and Schroeder, J.I. (2002). Convergence of calcium signaling pathways of pathogenic elicitors and abscisic acid in Arabidopsis guard cells. Plant Physiol 130,2152-2163.
Kobayashi, M., Ohura, I., Kawakita, K., Yokota, N., Fujiwara, M., Shimamoto, K., Doke, N., and Yoshioka, H. (2007). Calcium-dependent protein kinases regulate the production of reactive oxygen species by potato NADPH oxidase. Plant Cell 19,1065-1080.
Kolla, V., Vavasseur, A., and Raghavendra, A. (2007). Hydrogen peroxide production is an early event during bicarbonate induced stomatal closure in abaxial epidermis of Arabidopsis. Planta 225,1421-1429.
Kosugi, S., Hasebe,M., Matsumura, N., Takashima, H., Miyamoto-Sato, E., Tomita, M., and Yanagawa, H. (2008). Six classes of nuclear localization signals specific to different binding grooves of importin a. J Biol Chem 284,478-485.
Koussevitzky, S., Nott, A., Mockler, T.C., Hong, F., Sachetto-Martins, G., Surpin, M., Lim, J., Mittler, R., and Chory, J. (2007). Signals from chloroplasts converge to regulate nuclear gene expression. Science 316,715-719.
Kovtun, Y., Chiu, W.L., Tena, G., and Sheen, J. (2000). Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants. Proc Natl Acad Sci 97,2940-2945.
Krawczyk, S., Thurow, C., Niggeweg, R., and Gatz, C. (2002). Analysis of the spacing between the two palindromes of activation sequence-1 with respect to binding to different TGA factors and transcriptional activation potential. Nucleic Acids Res 30, 775-781.
Kroj, T., Rudd, J.J., Nurriberger, T., Gabler, Y., Lee, J., and Scheel, D. (2003). Mitogen-activated protein kinases play an essential role in oxidative burst-independent expression of pathogenesis-related genes in parsley. J Biol Chem 278,2256-2264.
Krysan, P.J., Jester, P.J., Gottwald, J.R., and Sussman, M.R. (2002). An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis. THE Plant Cell 14,1109-1120.
Kuge, S., Jones, N., and Nomoto, A. (1997). Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16, 1710-1720.
Kurepa, J., Herouart, D., van Montagu, M., and lnze, D. (1997). Differential expression of CuZn-and Fe-superoxide dismutase genes of tobacco during development, oxidative stress, and hormonal treatments. Plant Cell Physiol 38,463-470.
Kwak, J.M., Mori, I.C., Pei, Z.M., Leonhardt, N., Torres, M.A., Dangl, J.L., Bloom, R:E., Bodde, S., Jones, J.D.G., and Schroeder, J.I. (2003). NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis. EMBO J 22,2623-2633.
Lu, D., Zhang, X., Jiang, J., An, G., Zhang, L., and Song, C.-P. (2005). NO may function in the downstream of H2O2 in ABA-induced stomatal closure in Vicia faba L. J Plant Physiol Mol Biol 31,62-70.
Lang, V, and Palva, E.T. (1992). The expression of a rab-related gene, rabl8, is induced by abscisic acid during the cold acclimation process of Arabidopsis thaliana (L.) Heynh. Plant Mol Biol 20,951-962.
Leon-Kloosterziel, K.M., Gil, M.A., Ruijs, G.J., Jacobsen, S.E., Olszewski, N.E., Schwartz, S.H., Zeevaart, J.A.D., and Koornneef, M. (1996). Isolation and characterization of abscisic acid-deficient Arabidopsis mutants at two new loci. Plant J 10,655-661.
la Cour, T., Kiemer, L., Molgaard, A., Gupta, R., Skriver, K., and Brunak, S. (2004). Analysis and prediction of leucine-rich nuclear export signals. Protein Eng Des Sel 17,527-536.
Laby, R.J., Kincaid, M.S., Kim, D., and Gibson, S.I. (2000). The Arabidopsis sugar-insensitive mutants sis4 and sis5 are defective in abscisic acid synthesis and response. Plant J 23,587-596.
Laloi, C., Apel, K., and Danon, A, (2004). Reactive oxygen signalling:the latest news. Curr Opin Plant Biol 7,323-328.
Laloi, C., Stachowiak, M., Pers-Kamczyc, E., Warzych, E., Murgia, I., and Apel, K. (2007). Cross-talk between singlet oxygen-and hydrogen peroxide-dependent signaling of stress responses in Arabidopsis thaliana. Proc Natl Acad Sci 104,672-677.
Lam, E., Kato, N., and Lawton, M. (2001). Programmed cell death, mitochondria and the plant hypersensitive response. Nature 411, 848-853.
Lamb, C., and Dixon, R.A. (1997). the oxidative burst in plant disease resistance. Annu Rev Plant Physiol Plant Mol Biol 48, 251-275.
Lee, J., Rudd, J.J., Macioszek, V.K., and Scheel, D. (2004). Dynamic changes in the localization of MAPK cascade components controlling pathogenesis-related (PR) gene expression during innate immunity in parsley. J Biol Chem 279,22440-22448.
Lee, J.W., and Helmann, J.D. (2006). The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation. Nature 440, 363-367.
Lee, Y.-H., and Chun, J.-Y. (1998). A new homeodomain-leucine zipper gene from Arabidopsis thaliana induced by water stress and abscisic acid treatment. Plant Mol Biol 37,377-384.
Lee, Y., Bak, G., Choi, Y, Chuang, W.-I., Cho, H.-T., and Lee, Y. (2008). Roles of phosphatidylinositol 3-kinase in root hair growth. Plant Physiol 147,624-635.
Leonhardt, N., Kwak, J.M., Robert, N., Waner, D., Leonhardt, G., and Schroeder, J.I. (2004). Microarray expression analyses of Arabidopsis guard cells and isolation of a recessive abscisic acid hypersensitive protein phosphatase 2C mutant. Plant Cell 16, 596-615.
Levine, A., Pennell, R.I., Alvarez, M.E., Palmer, R., and Lamb, C. (1996). Calcium-mediated apoptosis in a plant hypersensitive disease resistance response. Curr Biol 6, 427-437.
Li, C., Chen, Q., Gao, X., Qi, B., Chen, N., Xu, S., Chen, J., and Wang, X. (2005). AtHsfA2 modulates expression of stress responsive genes and enhances tolerance to heat and oxidative stress in Arabidopsis. Sci China C Life Sci 48,540-550.
Li, H.-B., Qin, Y.-M., Pang, Y., Song, W.-Q., Mei, W.-Q., and Zhu, Y.-X. (2007). A cotton ascorbate peroxidase is involved in hydrogen peroxide homeostasis during fibre cell development. New Phytol 175,462-471.
Li, J.-H., Liu, Y.-Q., Lu, P., Lin, H.-F., Bai, Y, Wang, X.-C., and Chen, Y.-L. (2009). A signaling pathway linking nitric oxide production to heterotrimeric G protein and hydrogen peroxide regulates extracellular calmodulin induction of stomatal closure in Arabidopsis. Plant Physiol 150,114-124.
Liang, H., Yao, N., Song, J.T., Luo, S., Lu, H., and Greenberg, J.T. (2003). Ceramides modulate programmed cell death in plants. Genes Dev 17,2636-2641.
Lin, J., Wang, Y, and Wang, G. (2006). Salt stress-induced programmed cell death in tobacco protoplasts is mediated by reactive oxygen species and mitochondrial permeability transition pore status. J Plant Physiol 163,731-739.
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., and Shinozaki, K. (1998). Two transcription factors, DREB1 and DREB2, with an EREBP/AP2 DNA binding domain separate two cellular signal transduction pathways in drought- and low-temperature-responsive gene expression, respectively, in Arabidopsis. Plant Cell 10,1391-1406.
Locato, V., Gadaleta, C., Gara, L.D., And Pinto, M.C.D. (2008). Production of reactive species and modulation of antioxidant network in response to heat shock:a critical balance for cell fate. Plant Cell Environ 31,1606-1619.
Locato, V., Pinto, M.C.d., and Gara, L.D. (2009). Different involvement of the mitochondrial, plastidial and cytosolic ascorbate glutathione redox enzymes in heat shock responses. Physiol Plant 135,296-306.
Lorenzo, O., Piqueras, R., Sanchez-Serrano, J.J., and Solano, R. (2003). Ethylene Response Factorl integrates signals from ethylene and jasmonate pathways in plant defense. Plant Cell 15,165-178.
Lum, H.K., Butt, Y.K.C., and Lo, S.C.L. (2002). Hydrogen Peroxide Induces a Rapid Production of Nitric Oxide in Mung Bean (Phaseolus aureus). Nitric Oxide 6,205-213.
Muller, J., Beck, M., Mettbach, U., Komis, G., Hause, G., Menzel, D., and Samaj, J. (2009). Arabidopsis MPK6 is involved in cell division plane control during early root development and localizes to pre-prophase band, phragmoplast, trans-Golgi network and plasma membrane. Plant J 61,234-248.
Ma, Y, Szostkiewicz,I., Korte, A., Moes, D., Yang, Y., Christmann, A., and Grill, E. (2009). Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science 324,1064-1068.
Magnani, E., Sjolander, K., and Hake, S. (2004). From endonucleases to transcription factors:evolution of the AP2 DNA binding domain in plants. Plant Cell 16,2265-2277.
Magome, H., Yamaguchi, S., Hanada, A., Kamiya, Y., and Oda, K. (2004). dwarf and delayed-flowering I, a novel Arabidopsis mutant deficient in gibberellin biosynthesis because of overexpression of a putative AP2 transcription factor. Plant J 37, 720-729.
Maleck, K., Levine, A., Eulgem, T., Morgan, A., Schmid, J., Lawton, K.A., Dangl, J.L., and Dietrich, R.A. (2000). The transcriptome of Arabidopsis thaliana during systemic acquired resistance. Nat Genet 26,403-410.
Marechal, E., Hiratsuka, K., Delgado, J., Nairn, A., Qin, J., Chait, B., and Chua, N.-H. (1999). Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation. Plant Mol Biol 40,373-386.
Maxwell, D.P., Wang, Y, and McIntosh, L. (1999). The alternative oxidase lowers mitochondrial reactive oxygen production in plant cells. Proc Natl Acad Sci 96,8271-8276.
Mazel, A., Leshem, Y, Tiwari, B.S., and Levine, A. (2004). Induction of salt and osmotic stress tolerance by overexpression of an intracellular vesicle trafficking protein AtRab7 (AtRabG3e). Plant Physiol 134,118-128.
McAinsh, M.R., Clayton, H., Mansfield, T.A., and Hetherington, A.M. (1996). Changes in stomatal behavior and guard cell cytosolic free calcium in response to oxidative stress. Plant Physiol Ⅲ,1031-1042.
Meskauskiene, R., Nater, M., Goslings, D., Kessler, F., op den Camp, R., and Apel, K. (2001). FLU:a negative regulator of chlorophyll biosynthesis in Arabidopsis thaliana. Proc Natl Acad Sci 98,12826-12831.
Meyer, A., Puhler, A., and Niehaus, K. (2001). The lipopolysaccharides of the phytopathogen Xanthomonas campestris pv. campestris induce an oxidative burst reaction in cell cultures of Nicotiana tabacum. Planta 213,214-222.
Miao, Y., Laun, T., Smykowski, A., and Zentgraf, U. (2007). Arabidopsis MEKK1 can take a short cut:it can directly interact with senescence-related WRKY53 transcription factor on the protein level and can bind to its promoter. Plant Mol Biol 65,63-76.
Miao, Y., Lv, D., Wang, P., Wang, X.-C., Chen, J., Miao, C., and Song, C.-P. (2006). An Arabidopsis glutathione peroxidase functions as both a redox transducer and a scavenger in abscisic acid and drought stress responses. Plant Cell 18,2749-2766.
Millar, J.B., Buck, V., and Wilkinson, M.G. (1995). Pypl and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast. Genes Dev 9,2117-2130.
Miller, G.A.D., and Mittler, R.O.N. (2006). Could heat shock transcription factors function as hydrogen peroxide sensors in plants? Ann Bot 98,279-288.
Mittler, R., Kim, Y, Song, L., Coutu, J., Coutu, A., Ciftci-Yilmaz, S., Lee, H., Stevenson, B., and Zhu, J.K. (2006). Gain- and loss-of-function mutations in Zat10 enhance. the tolerance of plants to abiotic stress. FEBS Lett 580,6537-6542.
Miyazono, K.-i., Miyakawa, T., Sawano, Y., Kubota, K., Kang, H.-J., Asano, A., Miyauchi, Y., Takahashi, M., Zhi, Y., Fujita, Y., et al. (2009). Structural basis of abscisic acid signalling. Nature 462,609-614.
Monshausen, G.B., Bibikova, T.N., Weisenseel, M.H., and Gilroy, S. (2009). Ca2+ regulates reactive oxygen species production and pH during mechanosensing in Arabidopsis roots. Plant Cell 21,2341-2356.
Moon, H., Lee, B., Choi, G., Shin, D., Prasad, D.T., Lee, O., Kwak, S.-S., Kim, D.H., Nam, J., Bahk, J., et al. (2003). NDP kinase 2 interacts with two oxidative stress-activated MAPKs to regulate cellular redox state and enhances multiple stress tolerance in transgenic plants. Proc Natl Acad Sci 100,358-363.
Mori, I.C., and Schroeder, J.I. (2004). Reactive Oxygen Species Activation of plant Ca2+ channels. a signaling mechanism in polar growth, hormone transduction, stress signaling, and hypothetically mechanotransduction. Plant Physiol 135,702-708.
Motoaki, S., Junko,I., Mari, N., Miki, F., Tokihiko, N., Taishi, U., Asako, K., Maiko, N., Akiko, E., Tetsuya, S., et al. (2002). Monitoring the expression pattern of around 7,000 Arabidopsis genes under ABA treatments using a full-length cDNA microarray. Funct Integrat Genomics 2,282-291.
Mou, Z., Fan, W., and Dong, X. (2003). lnducers of plant systemic acquired resistance regulate NPR1 function through redox changes. Cell 113,935-944.
Mura, A., Medda, R., Longu, S., Floris, G., Rinaldi, A.C., and Padiglia, A. (2005). A Ca2+/calmodulin-binding peroxidase from Euphorbia Latex:novel aspects of calcium-hydrogen peroxide cross-talk in the regulation of plant defenses. Biochem 44, 14120-14130.
Murata, Y., Pei, Z.M., Mori, I.C., and Schroeder, J. (2001). Abscisic acid activation of plasma membrane Ca2+ channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abil-1 and abi2-1 protein phosphatase 2C mutants. Plant Cell 13,2513-2523.
Murgia, I., Delledonne, M., and Soave, C. (2002). Nitric oxide mediates iron-induced ferritin accumulation in Arabidopsis. Plant J 30,521-528.
Murgia, I., Tarantino, D., Vannini, C., Bracale, M., Carravieri, S., and Soave, C. (2004). Arabidopsis thaliana plants overexpressing thylakoidal ascorbate peroxidase show increased resistance to paraquat-induced photooxidative stress and to nitric oxide-induced cell death. Plant J 38,940-953.
Mustilli, A.-C., Merlot, S., Vavasseur, A., Fenzi, F., and Giraudat, J. (2002). Arabidopsis OST1 protein kinase mediates the regulation of stomatal aperture by abscisic acid and acts upstream of reactive oxygen species production. Plant Cell 14, 3089-3099.
Nemeth, K., Salchert, K., Putnoky, P., Bhalerao, R., Koncz-Kalman, Z., Stankovic-Stangeland, B., Bako, L., Mathur, J., Okresz, L., Stabel, S., et al. (1998). Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis. Genes Dev 12,3059-3073.
Nakagami, H., Kiegerl, S., and Hirt, H. (2004).OMTK1, a novel MAPKKK, channels oxidative stress signaling through direct MAPK interaction. J Biol Chem 279,26959-26966.
Nakagami, H., Soukupova, H., Schikora, A., Zarsky, V, and Hirt, H. (2006). a mitogen-activated protein kinase kinase kinase mediates reactive oxygen species homeostasis in Arabidopsis. J Biol Chem 281,38697-38704.
Nakano, T., Suzuki, K., Fujimura, T., and Shinshi, H. (2006). Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol 140,411-432.
Neill, S., Desikan, R., and Hancock, J. (2002). Hydrogen peroxide signalling. Curr Opin Plant Biol 5,388-395.
Neill, S.J., Desikan, R., and Hancock, J.T. (2003). Nitric oxide signalling in plants. New Phytol 159,11-35.
Nguyen, A.N., Lee, A., Place, W., and Shiozaki, K. (2000). Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase. Mol Biol Cell 11,1169-1181.
Ning, J., Li, X., Hicks, L.M., and Xiong, L. (2010). A raf-like MAPKKK gene DSM1 mediates drought resistance through reactive oxygen species scavenging in rice. Plant Physiol 152,876-890.
Ogasawara, Y., Kaya, H., Hiraoka, G, Yumoto, F., Kimura, S., Kadota, Y, Hishinuma, H., Senzaki, E., Yamagoe, S., Nagata, K.,. et al. (2008). Synergistic activation of the Arabidopsis NADPH oxidase AtrbohD by Ca2+ and Phosphorylation. J Biol Chem 283, 8885-8892.
Olsson, A., Engstrom, P., and Soderman, E. (2004). The homeobox genes ATHB12 and ATHB7 encode potential regulators of growth in response to water deficit in Arabidopsis. Plant Mol Biol 55,663-677.
Onate-Sanchez, L., Anderson, J.P., Young, J., and Singh, K.B. (2007). AtERF14, a member of the erf family of transcription factors, plays a nonredundant role in plant defense. Plant Physiol 143,400-409.
op den Camp, R.G.L., Przybyla, D., Ochsenbein, C., Laloi, C., Kim, C., Danon, A., Wagner, D., Hideg, E., Gobel, C., Feussner,I., et al. (2003). Rapid induction of distinct stress responses after the release of singlet oxygen in Arabidopsis. Plant Cell 15, 2320-2332.
Orozco-Cardenas, M., and Ryan, C.A. (1999). Hydrogen peroxide is generated systemically in plant leaves by wounding and systemin via the octadecanoid pathway. Proc Natl Acad Sci 96,6553-6557.
Ortiz-Masia, D., Perez-Amador, M.A., Carbonell, J., and Marcote, M.J. (2007). Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis. FEBS Lett 581,1834-1840.
Palmieri, M.C., Sell, S., Huang, X., Scherf, M., Werner, T., Durner, J., and Lindermayr, C. (2008). Nitric oxide-responsive genes and promoters in Arabidopsis thaliana:a bioinformatics approach. J Exp Bot,59,117-186.
Panchuk, I.I., Volkov, R.A., and Schoffl, F. (2002). Heat stress- and heat shock transcription factor-dependent expression and activity of ascorbate peroxidase in Arabidopsis. Plant Physiol 129,838-853.
Pandey, G.K., Cheong, Y.H., Kim, K.N., Grant, J.J., Li, L., Hung, W., D'Angelo, C., Weinl, S., Kudla, J., and Luan, S. (2004). The calcium sensor calcineurin B-like 9 modulates abscisic acid sensitivity and biosynthesis in Arabidopsis. Plant Cell 16, 1912-1924.
Pandey, S., Nelson, D.C., and Assmann, S.M. (2009). Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis. Cell 136,136-148.
Pang, Q., Hays, J.B., and Rajagopal,1. (1993). Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E.coli mutants lacking recombination-intermediate-resolution activities. Nucleic Acids Res 21,1647-1653.
Park, J., Gu, Y., Lee, Y., Yang, Z., and Lee, Y. (2004). Phosphatidic acid induces leaf cell death in Arabidopsis by activating the Rho-related small G protein GTPase-mediated pathway of reactive oxygen species generation. Plant Physiol 134,129-136.
Park, K.-Y, Jung, J.-Y, Park, J., Hwang, J.-U., Kim, Y.-W., Hwang,I., and Lee, Y (2003). A role for phosphatidylinositol 3-phosphate in abscisic acid-induced reactive oxygen species generation in guard cells. Plant Physiol 132,92-98.
Park, S.-Y, Fung, P., Nishimura, N., Jensen, D.R., Fujii, H., Zhao, Y, Lumba, S., Santiago, J., Rodrigues, A., Chow, T.-f.F., et al. (2009). Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins. Science 324, 1068-1071.
Parker, J.E., Holub, E.B., Frost, L.N., Falk, A., Gunn, N.D., and Daniels, M.J. (1996). Characterization of edsl, a mutation in Arabidopsis suppressing resistance to Peronospora parasitica Specified by several different RPP genes. Plant Cell 8, 2033-2046.
Pavet, V, Olmos, E., Kiddle, G., Mowla, S., Kumar, S., Antoniw, J., Alvarez, M.E., and Foyer, C.H. (2005). Ascorbic acid deficiency activates cell death and disease resistance responses in Arabidopsis. Plant Physiol 139,1291-1303.
Pei, Z.-M., Murata, Y., Benning, G., Thomine, S., Klusener, B., Allen, G.J., Grill, E., and Schroeder, J.I. (2000). Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells. Nature 406,731-734.
Peltier, J.-B., Emanuelsson, O., Kalume, D.E., Ytterberg, J., Friso, G., Rudella, A., Liberles, D.A., Soderberg, L., Roepstorff, P., von Heijne, G, et al. (2002). Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction, plant cell 14,211-236.
Pieterse, C.M.J., and Van Loon, L.C. (2004). NPR1:the spider in the web of induced resistance signaling pathways. Curr Opin Plant Biol 7,456-464.
Pnueli, L., Liang, H., Rozenberg, M., and Mittler, R. (2003). Growth suppression, altered stomatal responses, and augmented induction of heat shock proteins in cytosolic ascorbate peroxidase (Apxl)-deficient Arabidopsis plants. Plant J 34,187-203.
Pomposiello, P.J., and Demple, B. (2001). Redox-operated genetic switches:the SoxR and OxyR transcription factors. Trends Biotech 19,109-114.
Popescu, S.C., Popescu, GV., Bachan, S., Zhang, Z., Gerstein, M., Snyder, M., and Dinesh-Kumar, S.P. (2009). MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Genes Dev 23,80-92.
Potocky, M., Jones, M.A., Bezvoda, R., Smirnoff, N., and Zarsky, V. (2007). Reactive oxygen species produced by NADPH oxidase are involved in pollen tube growth. New Phytol 174,742-751.
Price, A.H., Taylor, A., Ripley, S.J., Griffiths, A., Trewavas, A.J., and Knight, M.R. (1994). Oxidative signals in tobacco increase cytosolic calcium. Plant Cell 6,1301-1310.
Purvis, A.C. (1997). Role of the alternative oxidase in limiting superoxide production by plant mitochondria. Physiol Plant 100, 165-170.
Rashotte, A.M., DeLong, A., and Muday, GK. (2001). Genetic and chemical reductions in protein phosphatase activity alter auxin transport, gravity response, and lateral root growth. Plant Cell 13,1683-1697.
Ren, D., Liu, Y., Yang, K.-Y, Han, L., Mao, G, Glazebrook, J., and Zhang, S. (2008). A fungal-responsive MAPK cascade regulates phytoalexin biosynthesis in Arabidopsis. Proc Natl Acad Sci 105,5638-5643.
Ren, D., Yang, H., and Zhang, S. (2002). Cell death mediated by MAPK is associated with hydrogen peroxide production in Arabidopsis. J Biol Chem 277,559-565.
Rentel, M.C., and Knight, M.R. (2004). Oxidative stress-induced calcium signaling in Arabidopsis. Plant Physiol 135,1471-1479.
Rentel, M.C., Lecourieux, D., Ouaked, F., Usher, S.L., Petersen, L., Okamoto, H., Knight, H., Peck, S.C., Grierson, C.S., Hirt, H., et al. (2004). OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis. Nature 427,858-861.
Riechmann, J.L., Heard, J., Martin, G, Reuber, L., Z, C., Jiang, Keddie, J., Adam, L., Pineda, O., Ratcliffe, O.J., et al. (2000). Arabidopsis transcription factors:genome-wide comparative analysis among eukaryotes. Science 290,2105-2110.
Rizhsky, L., Davletova, S., Liang, H., and Mittler, R. (2004). The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis. J Biol Chem 279,11736-11743.
Rizhsky, L., Hallak-Herr, E., Van Breusegem, F., Rachmilevitch, S., Barr, J.E., Rodermel, S., Inze, D., and Mittler, R. (2002). Double antisense plants lacking ascorbate peroxidase and catalase are less sensitive to oxidative stress than single antisense plants lacking ascorbate peroxidase or catalase. Plant J 32,329-342.
Rizhsky, L., Liang, H., and Mittler, R. (2003). The water-water cycle is essential for chloroplast protection in the absence of stress. J Biol Chem 278,38921-38925.
Rook, F., Corke, F., Card, R., Munz, G, Smith, C., and Bevan, M.W. (2001). Impaired sucrose-induction mutants reveal the modulation of sugar-induced starch biosynthetic gene expression by abscisic acid signalling. Plant J 26,421-433.
Rossel, J.B., Wilson, P.B., Hussain, D., Woo, N.S., Gordon, M.J., Mewett, O.P., Howell, K.A., Whelan, J., Kazan, K., and Pogson, B.J. (2007). Systemic and Intracellular Responses to Photooxidative Stress in Arabidopsis. Plant Cell 19,4091-4110.
Rouse, D.T., Marotta, R., and Parish, R.W. (1996). Promoter and expression studies on an Arabidopsis thaliana dehydrin gene. FEBS Lett 381,252-256.
Rubinstein, B., and Luster, D.G (1993). Plasma membrane redox activity:components and role in plant processes. Annu Rev Plant Physiol Plant Mol Biol 44,131-155.
Ruelland, E., and Miginiac-Maslow, M. (1999). Regulation of chloroplast enzyme activities by thioredoxins:activation or relief from inhibition? Trends Plant Sci 4,136-141.
Salchert, K. (1998). Control of cell elongation and stress responses by steroid hormones and carbon catabolic repression in plants. Philos T R Soc B:Biol Sci 353,1517-1520.
Samadi, L., and Shahsavan Behboodi, B. (2006). Fusaric acid induces apoptosis in saffron root-tip cells:roles of caspase-like activity, cytochrome c, and H2O2. Planta 225,223-234.
Samuel, M.A., and Ellis, B.E. (2002). Double Jeopardy:Both overexpression and suppression of a redox-activated plant mitogen-activated protein kinase render tobacco plants ozone sensitive. Plant Cell 14,2059-2069.
Samuel, M.A., Hall, H., Krzymowska, M., Drzewiecka, K., Hennig, J., and Ellis, B.E. (2005). SIPK signaling controls multiple components of harpin-induced cell death in tobacco. Plant J 42,406-416.
Samuilov, V.D., Kiselevsky, D.B., Sinitsyn, S.V., Shestak, A.A., Lagunova, E.M., and Nesov, A.V. (2006). H2O2 intensifies CN--induced apoptosis in pea leaves. Biochem 71,384-394.
Scarpeci, T., Zanor, M., Carrillo, N., Mueller-Roeber, B., and Valle, E. (2008). Generation of superoxide anion in chloroplasts of Arabidopsis thaliana during active photosynthesis:a focus on rapidly induced genes. Plant Mol Biol 66,361-378.
Schindler, U., Beckmann, H., and Cashmore, A.R. (1992). TGA1 and g-box binding factors:two distinct classes of Arabidopsis leucine zipper proteins compete for the G-box-like element TGACGTGG Plant Cell 4,1309-1319.
Schopfer, P., Plachy, C., and Frahry, G (2001). Release of reactive oxygen intermediates (superoxide radicals, hydrogen peroxide, and hydroxyl radicals) and peroxidase in germinating radish seeds controlled by light, gibberellin, and abscisic acid. Plant Physiol 125,1591-1602.
Schreck, R., Rieber, P., and Baeuerle, P.A. (1991). Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J 10,2247-2258.
Schroeder, J.I., Kwak, J.M., and Allen, GJ. (2001). Guard cell abscisic acid signalling and engineering drought hardiness in plants. Nature 410,327-330.
Schubert, M., Petersson, U.A., Haas, B.J., Funk, C., Schroder, W.P., and Kieselbach, T. (2002). Proteome map of the chloroplast lumen of Arabidopsis thaliana. J Biol Chem 277,8354-8365.
Segal, A. W., and Abo, A. (1993). The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem Sci 18,43-47.
Sharma, Y.K., Leon, J., Raskin, I., and Davis, K.R. (1996). Ozone-induced responses in Arabidopsis thaliana:The role of salicylic acid in the accumulation of defense-related transcripts and induced resistance. Proc Natl Acad Sci 93,5099-5104.
Sharp, R.E., LeNoble, M.E., Else, M.A., Thorne, E.T., and Gherardi, F. (2000). Endogenous ABA maintains shoot growth in tomato independently of effects on plant water balance:evidence for an interaction with ethylene. J Exp Bot 51,1575-1584.
Sharrocks, A.D., Yang, S.-H., and Galanis, A. (2000). Docking domains and substrate-specificity determination for MAP kinases. Trends Biochem Sci 25,448-453.
She, X.-P., Song, X., and He, J. (2004). Role and relationship of nitric oxide and hydrogen peroxide in light/dark-regulated stomatal movement in Vicia faba. Acta botanica sinica 46,1292-1300.
Sheen, J., Zhou, L., and Jang, J.C. (1999). Sugars as signaling molecules. Curr Opin Plant Biol 2,410-418.
Shilo, S., Roy, S., Khanna, S., and Sen, C.K. (2008). Evidence for the involvement of mirna in redox regulated angiogenic response of human microvascular endothelial cells. Arterioscler Thromb Vasc Biol 28,471-477.
Shiozaki, K., and Russell, P. (1996). Conjugation, meiosis, and the osmotic stress response are regulated by Spcl kinase through Atfl transcription factor in fission yeast. Genes Dev 10,2276-2288.
Sirichandra, C., Gu, D., Hu, H.-C., Davanture, M., Lee, S., Djaoui, M., Valot, B., Zivy, M., Leung, J., Merlot, S., et al. (2009). Phosphorylation of the Arabidopsis AtrbohF NADPH oxidase by OST1 protein kinase. FEBS Lett 583,2982-2986.
Solano, R., Stepanova, A., Chao, Q., and Ecker, J.R. (1998). Nuclear events in ethylene signaling:a transcriptional cascade mediated by Ethylene-insensitive3 and ethylene-response-factorl. Genes Dev 12,3703-3714.
Soncin, F., Zhang, X., Chu, B., Wang, X., Asea, A., Ann Stevenson, M., Sacks, D.B., and Calderwood, S.K. (2003). Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2. Biochem Biophy Res Commun 303,700-706.
Song, C.-P., Agarwal, M., Ohta, M., Guo, Y., Halfter, U., Wang, P., and Zhu, J.-K. (2005). Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Plant Cell 17,2384-2396.
Sorger, P.K., and Pelham, H.R.B. (1988). Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation. Cell 54,855-864.
Spassieva, S.D., Markham, J.E., and Hille, J. (2002). The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death. Plant J 32,561-572.
Stanley, K.H., Yu, Y, Snesrud, E.C., Moy, L.P., Linford, L.D., Haas, B.J., Nierman, W.C., and Quackenbush, J. (2005). Transcriptional divergence of the duplicated oxidative stress-responsive genes in the Arabidopsis genome. Plant J 41,212-220.
Stimberg, P., van de Sande, K., and Leyser, H.M.O. (2002). MAX1 and MAX2 control shoot lateral branching in Arabidopsis. Development 129,1131-1141.
Stockinger, E.J., Gilmour, S.J., and Thomashow, M.F. (1997). Arabidopsis thaliana CBF1 encodes an AP2 domain-containing transcriptional activator that binds to the C-repeat/DRE, a cis-acting DNA regulatory element that stimulates transcription in response to low temperature and water deficit. Proc Natl Acad Sci 94,1035-1040.
Sugie, A., Naydenov, N., Mizuno, N., Nakamura, C., and Takumi, S. (2006). Overexpression of wheat alternative oxidase gene Waoxla alters respiration capacity and response to reactive oxygen species under low temperature in transgenic Arabidopsis. Genes Genet Syst 81,349-354.
Tada, Y, Mori, T., Shinogi, T., Yao, N., Takahashi, S., Betsuyaku, S., Sakamoto, M., Park, P., Nakayashiki, H., Tosa, Y, et al. (2004). Nitric oxide and reactive oxygen species do not elicit hypersensitive cell death but induce apoptosis in the adjacent cells during the defense response of Oat. Mol Plant-Microbe Interac 17,245-253.
Tada, Y, Spoel, S.H., Pajerowska-Mukhtar, K., Mou, Z., Song, J., Wang, C, Zuo, J., and Dong, X. (2008). Plant immunity requires conformational charges of NPR1 via S-nitrosylation and thioredoxins. Science 321,952-956.
Takahashi, S., Seki, M., Ishida, J., Satou, M., Sakurai, T., Narusaka, M., Kamiya, A., Nakajima, M., Enju, A., Akiyama, K., et al. (2004). Monitoring the expression profiles of genes induced by hyperosmotic, high salinity, and oxidative stress and abscisic acid treatment in Arabidopsis cell culture using a full-length cDNA microarray. Plant Mol Biol 56,29-55.
Takeda, S., Gapper, C., Kaya, H., Bell, E., Kuchitsu, K., and Dolan, L. (2008). Local positive feedback regulation determines cell shape in root hair cells. Science 319,1241-1244.
Tena, G, Asai, T., Chiu, W.L., and Sheen, J. (2001). Plant mitogen-activated protein kinase signaling cascades. Curr Opin Plant Biol 4,392-400.
Toledano, M.B., Delaunay, A., Monceau, L., and Tacnet, F. (2004). Microbial H2O2 sensors as archetypical redox signaling modules. Trends Biochem Sci 29,351-357.
Torres, M. (2003). Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 8,369-391.
Torres, M.A., Dangl, J.L., and Jones, J.D.G (2002). Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response. Proc Natl Acad Sci 99,517-522.
Torres, M.A., Onouchi, H., Hamada, S., Machida, C, Hammond-Kosack, K.E., and Jones, J.D.G (1998). Six Arabidopsis thaliana homologues of the human respiratory burst oxidase (gp91phox). Plant J 14,365-370.
Tsukamoto, S., Morita, S., Hirano, E., Yokoi, H., Masumura, T., and Tanaka, K. (2005). A Novel cis-element that is responsive to oxidative stress regulates three antioxidant defense genes in rice. Plant Physiol 137,317-327.
Ulker, B., and Somssich, I.E. (2004). WRKY transcription factors:from DNA binding towards biological function. Curr Opin Plant Biol 7,491-498.
Umbach, A.L., Fiorani, F., and Siedow, J.N. (2005). Characterization of transformed Arabidopsis with altered alternative oxidase levels and analysis of effects on reactive oxygen species in tissue. Plant Physiol 139,1806-1820.
Umezawa, T., Sugiyama, N., Mizoguchi, M., Hayashi, S., Myouga, F., Yamaguchi-Shinozaki, K., Ishihama, Y, Hirayama, T., and Shinozaki, K. (2009). Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis. Proc Natl Acad Sci 106,17588-17593.
Uno, Y, Furihata, T., Abe, H., Yoshida, R., Shinozaki, K., and Yamaguchi-Shinozaki, K. (2000). Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions. Proc Natl Acad Sci 97,11632-11637.
Vacca, R.A., de Pinto, M.C., Valenti, D., Passarella, S., Marra, E., and De Gara, L. (2004). Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco bright-yellow 2 cells. Plant Physiol 134,1100-1112.
Vahisalu, T., Kollist, H., Wang, Y.-F., Nishimura, N., Chan, W.-Y, Valerio, G., Lamminmaki, A., Brosche, M., Moldau, H., Desikan, R., et al. (2008). SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling. Nature 452, 487-491.
Vahisalu, T., Puzorjova, I., Brosche, M., Valk, E., Lepiku, M., Moldau, H., Pechter, P., Wang, Y.-S., Lindgren, O., Salojarvi, J., et al. (2010). Ozone-triggered rapid stomatal response involves the production of reactive oxygen species, and is controlled by SLAC1 and OSTI. Plant J 62,442-453.
Vandenabeele, S., Van Der Kelen, K., Dat, J., Gadjev, I., Boonefaes, T., Morsa, S., Rottiers, P., Slooten, L., Van Montagu, M., Zabeau, M., et al. (2003). A comprehensive analysis of hydrogen peroxide-induced gene expression in tobacco. Proc Natl Acad Sci 100,16113-16118.
Vandenabeele, S., Vanderauwera, S., Vuylsteke, M., Rombauts, S., Langebartels, C., Seidlitz, H.K., Zabeau, M., Van Montagu, M., Inze, D., and Van Breusegem, F. (2004). Catalase deficiency drastically affects gene expression induced by high light in Arabidopsis thaliana. Plant J 39,45-58.
Vanderauwera, S., Zimmermann, P., Rombauts, S., Vandenabeele, S., Langebartels, C., Gruissem, W., Inze, D., and Van Breusegem, F. (2005). Genome-wide analysis of hydrogen peroxide-regulated gene expression in arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis. Plant Physiol 139,806-821.
Vannini, C., Iriti, M., Bracale, M., Locatelli, F., Faoro, F., Croce, P., Pirona, R., Di Maro, A., Coraggio, I., and Genga, A. (2006). The ectopic expression of the rice Osmyb4 gene in Arabidopsis increases tolerance to abiotic, environmental and biotic stresses. Physiol Mol Plant Pathol 69,26-42.
Vivancos, A.P., Castillo, E.A., Biteau, B., Nicot, C., Ayte, J., Toledano, M.B., and Hidalgo, E. (2005). A cysteine-sulfinic acid in peroxiredoxin regulates H2O2-sensing by the antioxidant Papl pathway. Proc Natl Acad Scis 102,8875-8880.
Vogel, J., Zarka, D., Van Buskirk, H., Fowler, S., and Thomashow, M. (2005). Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis. Plant J 41,195-211.
Volkov, R., Panchuk, I., Mullineaux, P., and Schoffl, F. (2006). Heat stress-induced H2O2 is required for effective expression of heat shock genes in Arabidopsis. Plant Mol Biol 61,733-746.
Wagner, D., Przybyla, D., op den Camp, R., Kim, C., Landgraf, F., Lee, K.P., Wursch, M., Laloi, C., Nater, M., Hideg, E., et al. (2004). The genetic basis of singlet oxygen-induced stress responses of Arabidopsis thaliana. Science 306,1183-1185.
Wang, H., Liu, Y., Bruffett, K., Lee, J., Hause, G., Walker, J.C., and Zhang, S. (2008a). Haplo-insufficiency of MPK3 in MPK6 mutant background uncovers a novel function of these two MAPKs in Arabidopsis ovule development. Plant Cell 20,602-613.
Wang, P.-C., Du, Y.-Y, An, G.-Y., Zhou, Y, Miao, C., and Song, C.-P. (2006). analysis of global expression profiles of Arabidopsis genes under abscisic acid and H2O2 Applications. J Integrat Plant Biol 48,62-74.
Wang, P., and Song, C.-P. (2008). Guard-cell signalling for hydrogen peroxide and abscisic acid. New Phytol 178,703-718.
Wang, Q., Guan, Y, Wu, Y., Chen, H., Chen, F., and Chu, C. (2008b). Overexpression of a rice OsDREBIF gene increases salt, drought, and low temperature tolerance in both Arabidopsis and rice. Plant Molecular Biology 67,589-602.
Wasner, M., Haugwitz, U., Reinhard, W., Tschop, K., Spiesbach, K., Lorenz, J., Mossner, J., and Engeland, K. (2003). Three CCAAT-boxes and a single cell cycle genes homology region (CHR) are the major regulating sites for transcription from the human cyclin B2 promoter. Gene 312,225-237.
Whitbred, J.M., and Schuler, M.A. (2000). Molecular Characterization of CYP73A9 and CYP82A1 P450 genes involved in plant defense in pea. Plant Physiol 124,47-58.
Wisniewski, J.-P., Cornille, P., Agnel, J.-P., and Montillet, J.-L. (1999). The extensin multigene family responds differentially to superoxide or hydrogen peroxide in tomato cell cultures. FEBS Lett 447,264-268.
Wojtaszek, P. (1997). Oxidative burst:an early plant response to pathogen infection. Biochem J 322 (Pt 3),681-692.
Woo, H.R., Kim, J.H., Nam, H.G, and Lim, P.O. (2004). The delayed leaf senescence mutants of Arabidopsis, orel, ore3, and ore9 are tolerant to oxidative stress. Plant Cell Physiol 45,923-932.
Xing, Y., Jia, W., and Zhang, J. (2007). AtMEKl mediates stress-induced gene expression of CAT1 catalase by triggering H2O2 production in Arabidopsis. J Exp Bot 58,2969-2981.
Xing, Y, Jia, W., and Zhang, J. (2008). AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis. Plant J 54,440-451.
Yamaguchi-Shinozaki, K., and Shinozaki, K. (2005). Organization of cis-acting regulatory elements in osmotic-and cold-stress-responsive promoters. Trends Plant Sci 10,88-94.
Yan, C., Lee, L.H., and Davis, L. (1998). Crmlp mediates regulated nuclear export of a yeast AP-1-like transcription factor. EMBO J 17,7416-7429.
Yang, T., and Poovaiah, B.W. (2002). Hydrogen peroxide homeostasis:Activation of plant catalase by calcium/calmodulin. Proc Natl Acad Sci 99,4097-4102.
Yang, Z., Tian, L.,Latoszek-Green, M., Brown, D., and Wu, K. (2005). Arabidopsis ERF4 is a transcriptional repressor capable of modulating ethylene and abscisic acid responses. Plant Mol Biol 58,585-596.
Yin, P., Fan, H., Hao, Q., Yuan, X., Wu, D., Pang, Y., Yan, C., Li, W., Wang, J., and Yan, N. (2009). Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol 16,1230-1236.
Yoo, S.-D., Cho, Y.-H., Tena, G., Xiong, Y, and Sheen, J. (2008). Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling. Nature 451,789-795.
Yoshida, K., Terashima, I., and Noguchi, K. (2007). Up-regulation of mitochondrial alternative oxidase concomitant with chloroplast over-reduction by excess light. Plant Cell Physiol 48,606-614.
Yuasa, T., Ichimura, K., Mizoguchi, T., and Shinozaki, K. (2001). Oxidative Stress Activates ATMPK6, an Arabidopsis Homologue of MAP Kinase. Plant Cell Physiol 42,1012-1016.
Zhang, A., Jiang, M., Zhang, J., Ding, H., Xu, S., Hu, X., and Tan, M. (2007). Nitric oxide induced by hydrogen peroxide mediates abscisic acid-induced activation of the mitogen-activated protein kinase cascade involved in antioxidant defense in maize leaves. New Phytol 175,36-50.
Zhang, B., Chen, W., Foley, R.C., Buttner, M., and Singh, K.B. (1995). Interactions between distinct types of DNA binding proteins enhance binding to ocs element promoter sequences. Plant Cell 7,2241-2252.
Zhang, S., and Klessig, D.F. (2001). MAPK cascades in plant defense signaling. Trends Plant Sci 6,520-527.
Zhang, W., Ruan, J., Ho, T.-h.D., You, Y, Yu, T., and Quatrano, R.S. (2005). Cis-regulatory element based targeted gene finding: genome-wide identification of abscisic acid- and abiotic stress-responsive genes in Arabidopsis thaliana. Bioinformatics 21, 3074-3081.
Zhang, X., Dong, F.C., Gao, J.F., and Song, C.P. (2001a). Hydrogen peroxide-induced changes in intracellular pH of guard cells precede stomatal closure. Cell Res 11,37-43.
Zhang, X., Miao, Y.C., An, GY, Zhou, Y., Shangguan, Z.P., Gao, J.F., and Song, C.P. (2001b). K+ channels inhibited by hydrogen peroxide mediate abscisic acid signaling in Vicia guard cells. Cell Res 11,195-202.
Zhang, X., Zhang, L., Dong, F., Gao, J., Galbraith, D.W., and Song, C.P. (2001c). Hydrogen peroxide is involved in abscisic acid-induced stomatal closure in Vicia faba. Plant Physiol 126,1438-1448.
Zhao, J., Zhang, W., Zhao, Y, Gong, X., Guo, L., Zhu, G, Wang, X., Gong, Z., Schumaker, K.S., and Guo, Y. (2007). SAD2, an importin-like protein, is required for UV-B response in Arabidopsis by mediating MYB4 nuclear trafficking. Plant Cell 19, 3805-3818.
Zheng, M., Aring, slund, F., and Storz, G.(1998). Activation of the OxyR transcription factor by reversible disulfide bond formation. Science 279,1718-1722.
Zheng, Z., Mosher, S., Fan, B., Klessig, D., and Chen, Z. (2007). Functional analysis of Arabidopsis WRKY25 transcription factor in plant defense against Pseudomonas syringae. BMC Plant Biol 7,2.
Zhou, D.-X. (1999). Regulatory mechanism of plant gene transcription by GT-elements and GT-factors. Trends Plant Sci 4,210-214.
Zhou, L., Jang, J.-c., Jones, T.L., and Sheen, J. (1998). Glucose and ethylene signal transduction crosstalk revealed by an Arabidopsis glucose-insensitive mutant. Proc Natl Acad Sci 95,10294-10299.
Abe, H., Yamaguchi-Shinozaki, K., Urao, T., lwasaki, T., Hosokawa, D., and Shinozaki, K. (1997). Role of Arabidopsis MYC and MYB homologs in drought-and abscisic acid-regulated gene expression. Plant Cell 9,1859-1868.
Achard, P., Renou, J.-P., Berthom, R., Harberd, N.P., and Genschik, P. (2008). Plant DELLAs restrain growth and promote survival of adversity by reducing the levels of reactive oxygen Species. Curr Biol 18,656-660.
Agarwal, P., Agarwal, P., Nair, S., Sopory, S., and Reddy, M. (2007), Stress-inducible DREB2A transcription factor from Pennisetum glaucum is a phosphoprotein and its phosphorylation negatively regulates its DNA-binding activity. Mol Genet Genomics 277,189-198.
Ahlfors, R., Macioszek, V., Rudd, J., Brosche, M., Schlichting, R., Scheel, D., and Kangasjarvi, J. (2004). Stress hormone-independent activation and nuclear translocation of mitogen-activated protein kinases in Arabidopsis thaliana during ozone exposure. Plant J 40,512-522.
Andreasson, E., Jenkins, T., Brodersen, P., Thorgrimsen, S., Petersen, N.H., Zhu, S., Qiu, J.L., Micheelsen, P., Rocher, A., Petersen, M., et al. (2005). The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO J 24,2579-2589.
Angelini, R., Tisi, A., Rea, G., Chen, M.M., Botta, M., Federico, R., and Cona, A. (2008). Involvement of polyamine oxidase in wound healing. Plant Physiol 146,162-177.
Apel, K., and Hirt, H. (2004). Reactive oxygen species:metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol 55,373-399.
Arenas-Huertero, F., Arroyo, A., Zhou, L., Sheen, J., and Leon, P. (2000). Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar. Genes Dev 14,2085-2096.
Asai, T., Tena, G., Plotnikova, J., Willmann, M.R., Chiu, W.-L., Gomez-Gomez, L., Boller, T., Ausubel, F.M., and Sheen, J. (2002). MAP kinase signalling cascade in Arabidopsis innate immunity. Nature 415,977-983.
Aslund, F., Zheng, M., Beckwith, J., and Storz, G. (1999). Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status. Proc Natl Acad Sci 96,6161-6165.
Assmann, S.M. (2003). OPEN STOMATA1 opens the door to ABA signaling in Arabidopsis guard cells. Trends Plant Sci 8, 151-153.
Bailey, T.L., and Elkan, C. (1994). Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 2,28-36.
Bardwell, L. (2006). Mechanisms of MAPK signalling specificity. In Biochemical Society Transactions, pp.837-841.
Baxter-Burrell, A., Yang, Z., Springer, P.S., and Bailey-Serres, J. (2002). RopGAP4-Dependent Rop GTPase rheostat control of Arabidopsis oxygen deprivation tolerance. Science 296,2026-2028.
Belles-Boix, E., Babiychuk, E., Van Montagu, M., Inz, D., and Kushnir, S. (2000). CEO1, a new protein from Arabidopsis thaliana, protects yeast against oxidative damage. FEBS Lett 482,19-24.
Berrin, J.-G, Pierrugues, O., Brutesco, C., Alonso, B., Montillet, J.-L., Roby, D., and Kazmaier, M. (2005). Stress induces the expression of AtNADK-1, a gene encoding a NAD(H) kinase in Arabidopsis thaliana. Mol Genet Genomics 273,10-19.
Bethke, G., Unthan, T., Uhrig, J.F., Poschl, Y., Gust, A. A., Scheel, D., and Lee, J. (2009). Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signaling. Proc Natl Acad Sci 106, 8067-8072.
Bozonet, S.M., Findlay, V.J., Day, A.M., Cameron, J., Veal, E.A., and Morgan, B.A. (2005). Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide. J Biol Chem 280,23319-23327.
Bright, J., Desikan, R., Hancock, J.T., Weir, I.S., and Neill, S.J. (2006). ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis. Plant J 45,113-122.
Brown, R.L., Kazan, K., McGrath, K.C., Maclean, D.J., and Manners, J.M. (2003). A role for the GCC-Box in jasmonate-mediated activation of the PDF1.2 gene of Arabidopsis. Plant Physiol 132,1020-1032.
Buck, V., Quinn, J., Pino, T.S., Martin, H., Saldanha, J., Makino, K., Morgan, B.A., and Millar, J.B.A. (2001). Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway. Mol Biol Cell 12,407-419.
Bulyk, M.L. (2006). DNA microarray technologies for measuring protein-DNA interactions. Curr Opin Biotec 17,422-430.
Buttner, M., and Singh, K.B. (1997). Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein. Proc Natl Acad Sci 94, 5961-5966.
Camilla, H., Paul, E.G., Silje, H.N., Tage, T., Marte, K.V., Vigdis, N., and Reidunn, B.A. (2003). ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress. Plant Mol Biol V53,313-326.
Cao, H., Bowling, S.A., Gordon, A.S., and Dong, X. (1994). Characterization of an Arabidopsis mutant that is nonresponsive to inducers of systemic acquired resistance. Plant Cell 6,1583-1592.
Cao, Y., Li, Z., Chen, T., Zhang, Z., Zhang, J., and Chen, S. (2008). Overexpression of a tobacco small G protein gene NtRopl causes salt sensitivity and hydrogen peroxide production in transgenic plants. Sci China Ser C Life Sci 51,383-390.
Casolo, V., Petrussa, E., Krajnakova, J., Macri, F., and Vianello, A. (2005). Involvement of the mitochondrial K(+)ATP channel in H2O2- or NO-induced programmed death of soybean suspension cell cultures. J Exp Bot 56,997-1006.
Chen, C., and Chen, Z. (2000). Isolation and characterization of two pathogen- and salicylic acid-induced genes encoding WRKY DNA-binding proteins from tobacco. Plant Mol Biol 42,387-396.
Chen, Y.-L., Huang, R., Xiao, Y.-M., Lu, P., Chen, J., and Wang, X.-C. (2004). Extracellular calmodulin-induced stomatal closure is mediated by heterotrimeric G protein and H2O2. Plant Physiol 136,4096-4103.
Chen, Z., Silva, H., and Klessig, D.F. (1993). Active oxygen species in the induction of plant systemic acquired resistance by salicylic acid. Science 262,1883-1886.
Cheng, C., Yun, K.-Y, Ressom, H., Mohanty, B., Bajic, V, Jia, Y, Yun, S., and de los Reyes, B. (2007). An early response regulatory cluster induced by low temperature and hydrogen peroxide in seedlings of chilling-tolerant japonica rice. BMC Genomics 8,175.
Cheng, Y., and Song, C. (2006). Hydrogen peroxide homeostasis and signaling in plant cells. Sci China C Life Sci 49,1-11.
Cheong, Y.H., Moon, B.C., Kim, J.K., Kim, C.Y, Kim, M.C., Kim, I.H., Park, C.Y., Kim, J.C., Park, B.O., Koo, S.C., et al. (2003). BWMK1, a rice mitogen-activated protein kinase, locates in the nucleus and mediates pathogenesis-related gene expression by activation of a transcription factor. Plant Physiol 132,1961-1972.
Ciftci-Yilmaz, S., Morsy, M.R., Song, L., Coutu, A., Krizek, B.A., Lewis, M.W., Warren, D., Cushman, J., Connolly, E.L., and Mittler, R. (2007). The EAR-motif of the Cys2/His2-type zinc finger protein ZAT7 plays a key role in the defense response of Arabidopsis to salinity stress. J Biol Chem 282,9260-9268.
Clark, D., Durner, J., Navarre, D.A., and Klessig, D.F. (2000). Nitric oxide inhibition of tobacco catalase and ascorbate peroxidase. . Mol Plant-Microbe Interact 13,1380-1384.
Clarke, A., Desikan, R., Hurst, R.D., Hancock, J.T., and Neill, S.J. (2000). NO way back:nitric oxide and programmed cell death in Arabidopsis thaliana suspension cultures. Plant J 24,667-677.
Coego, A., Ramirez, V, Ellul, P., Mayda, E., and Vera, P. (2005a). The H2O2-regulated Ep5C gene encodes a peroxidase required for bacterial speck susceptibility in tomato. Plant J 42,283-293.
Coego, A., Ramirez, V., Gil, M.J., Flors, V., Mauch-Mani, B., and Vera, P. (2005b). An Arabidopsis homeodomain transcription factor, OVEREXPRESSOR OF CATIONIC PEROXIDASE 3, mediates resistance to infection by necrotrophic pathogens. Plant Cell 17,2123-2137.
Coelho, S.M., Taylor, A.R., Ryan, K.P., Sousa-Pinto, I., Brown, M.T., and Brownlee, C. (2002). Spatiotemporal patterning of reactive oxygen production and Ca2+ wave propagation in Fucus Rhizoid Cells. Plant Cell 14,2369-2381.
Cona, A., Cenci, F., Cervelli, M., Federico, R., Mariottini, P., Moreno, S., and Angelini, R. (2003). Polyamine oxidase, a hydrogen peroxide-producing enzyme, is up-regulated by light and down-regulated by auxin in the outer tissues of the maize mesocotyl. Plant Physiol 131,803-813.
Crooks, G.E., Hon, G., Chandonia, J.-M., and Brenner, S.E. (2004). WebLogo:A Sequence Logo Generator. Genome Res 14, 1188-1190.
Diaz, M., Achkor, H., Titarenko, E., and Martinez, M.C. (2003). The gene encoding glutathione- dependent formaldehyde dehydrogenase/GSNO reductase is responsive to wounding, jasmonic acid and salicylic acid. FEBS Lett 543,136-139.
Doczi, R., Brader, G., Pettko-Szandtner, A., Rajh,I., Djamei, A., Pitzschke, A., Teige, M., and Hirt, H. (2007). The arabidopsis mitogen-activated protein kinase kinase mkk3 is upstream of group c mitogen-activated protein kinases and participates in pathogen signaling. Plant Cell 19,3266-3279.
Dejardin, A., Sokolov, L.N., and Kleczkowski, L.A. (1999). Sugar/osmoticum levels modulate differential abscisic acid-independent expression of two stress-responsive sucrose synthase genes in Arabidopsis:Biochem J 344,503-509.
Danon, A., Miersch, O., Felix, G., Camp, R.G.L., and Apel, K. (2005). Concurrent activation of cell death-regulating signaling pathways by singlet oxygen in Arabidopsis thaliana. Plant J 41,68-80.
Davletova, S., Rizhsky, L., Liang, H., Shengqiang, Z., Oliver, D.J., Coutu, J., Shulaev, V, Schlauch, K., and Mittler, R. (2005a). Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis. Plant Cell 17, 268-281.
Davletova, S., Schlauch, K., Coutu, J., and Mittler, R. (2005b). The zinc-finger protein Zatl2 plays a central role in reactive oxygen and abiotic stress signaling in Arabidopsis. Plant Physiol 139,847-856.
De Tullio, M.C., Jiang, K., and Feldman, L.J. (2010). Redox regulation of root apical meristem organization:Connecting root development to its environment. Plant Physiol Biochem In Press, Corrected Proof.
Degols, G., Shiozaki, K., and Russell, P. (1996). Activation and regulation of the Spcl stress-activated protein kinase in Schizosaccharomyces pombe. Mol Cell Biol 16,2870-2877.
Degterev, A., and Yuan, J. (2008). Expansion and evolution of cell death programmes. Nat Rev Mol Cell Biol 9,378-390.
del Rio, L.A., Corpas, F.J., Sandalio, L.M., Palma, J.M., Gomez, M., and Barroso, J.B. (2002). Reactive oxygen species, antioxidant systems and nitric oxide in peroxisomes. J Exp Bot 53,1255-1272.
Delaunay, A., Pflieger, D., Barrault, M.-B., Vinh, J., and Toledano, M.B. (2002). A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation. Cell Ⅲ,471-481.
Desikan, R., A.-H.-Mackerness, S., Hancock, J.T., and Neill, S.J. (2001). Regulation of the Arabidopsis Transcriptome by Oxidative Stress. Plant Physiol 127,159-172.
Desikan, R., Griffiths, R., Hancock, J., and Neill, S. (2002). A new role for an old enzyme:Nitrate reductase-mediated nitric oxide generation is required for abscisic acid-induced stomatal closure in Arabidopsis thaliana. Proc Natl Acad Sci 99,16314-16318.
Desikan, R., Hancock, J.T., Bright, J., Harrison, J., Weir, I., Hooley, R., and Neill, S.J. (2005). A Role for ETR1 in hydrogen peroxide signaling in stomatal guard cells. Plant Physiol 137,831-834.
Desikan, R., Neill, S.J., and Hancock, J.T. (2000). Hydrogen peroxide-induced gene expression in Arabidopsis thaliana. Free Radical Biol Med 28,773-778.
Desikan, R., Reynolds, A., Hancock, J.T., and Neill, S.J. (1998). Harpin and hydrogen peroxide both initiate programmed cell death but have differential effects on defence gene expression in Arabidopsis suspension cultures. Biochem J 330,115-120.
Despres, C., Chubak, C., Rochon, A., Clark, R., Bethune, T., Desveaux, D., and Fobert, P.R. (2003). The Arabidopsis NPR1 disease resistance protein is a novel cofactor that confers redox regulation of DNA binding activity to the basic domain/leucine zipper transcription factor TGA1. Plant Cell 15,2181-2191.
Despres, C., DeLong, C., Glaze, S., Liu, E., and Fobert, P.R. (2000). The Arabidopsis NPR1/NIMI protein enhances the dna binding activity of a subgroup of the TGA family of bZIP transcription tactors. Plant Cell 12,279-290.
Ding, H., Hidalgo, E., and Demple, B. (1996). The redox state of the [2Fe-2S] clusters in SoxR protein regulates its activity as a transcription factor. J Biol Chem 271,33173-33175.
Djamei, A., Pitzschke, A., Nakagami, H., Rajh, I., and Hirt, H. (2007). Trojan horse strategy in Agrobacterium transformation: abusing MAPK defense signaling. Science 318,453-456.
Dong, X. (2004). NPR1, all things considered. Curr Opin Plant Biol 7,547-552.
Du, Y.-Y., Wang, P.-C., Chen, J., and Song, C.-P. (2008). Comprehensive functional analysis of the catalase gene family in Arabidopsis thaliana. J Integrat Plant Biol 50,1318-1326.
Eshdat, Y., Holland, D., Faltin, Z., and Ben-Hayyim, G. (1997). Plant glutathione peroxidases. Physiol Plant 100,234-240.
Etienne, P., Petitot, A.-S., Houot, V., Blein, J.-P., and Suty, L. (2000). Induction of TCI 7, a gene encoding a β-subunit of proteasome, in tobacco plants treated with elicitins, salicylic acid or hydrogen peroxide. FEBS Lett 466,213-218.
Eulgem, T., Rushton, P.J., Schmelzer, E., Hahlbrock, K., and Somssich, I.E. (1999). Early nuclear events in plant defence signalling: rapid gene activation by WRKY transcription factors. EMBO J 18,4689-4699.
Eulgem, T., and Somssich, I.E. (2007). Networks of WRKY transcription factors in defense signaling. Curr Opin Plant Biol 10, 366-371.
Falk, A., Feys, B.J., Frost, L.N., Jones, J.D.G., Daniels, M.J., and Parker, J.E. (1999). EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases. Proc Natl Acad Sci 96,3292-3297.
Feilner, T., Hultschig, C., Lee,J., Meyer, S., Immink, R.G.H., Koenig, A., Possling, A., Seitz, H., Beveridge, A., Scheel, D., etal. (2005). High throughput identification of potential Arabidopsis mitogen-activated protein kinases substrates. Mol Cell Proteomics 4,1558-1568.
Fiil, B.K., Petersen, K., Petersen, M., and Mundy, J. (2009). Gene regulation by MAP kinase cascades. Curr Opin Plant Biol 12, 615-621.
Finkelstein, R.R., Gampala, S.S.L., and Rock, C.D. (2002). Abscisic acid signaling in seeds and seedlings. Plant Cell 14, S15-S45.
Fobert, P.R., and Despres, C. (2005). Redox control of systemic acquired resistance. Curr Opin Plant Biol 8,378-382.
Foreman, J., Demidchik, V, Bothwell, J.H.F., Mylona, P., Miedema, H., Torres, M.A., Linstead, P., Costa, S., Brownlee, C., Jones, J.D.G., et al. (2003). Reactive oxygen species produced by NADPH oxidase regulate plant cell growth. Nature 422,442-446.
Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, H., Hamann, T., Offringa, R., and Jurgens, G. (2003). Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis. Nature 426,147-153.
Fryer, M.J., Oxborough, K., Mullineaux, P.M., and Baker, N.R. (2002). Imaging of photo-oxidative stress responses in leaves. J Exp Bot 53,1249-1254.
Fuangthong, M., Atichartpongkul, S., Mongkolsuk, S., and Helmann, J.D. (2001). OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis. J Bacteriol 183,4134-4141.
Fujii, H., Chinnusamy, V., Rodrigues, A., Rubio, S., Antoni, R., Park, S.-Y, Cutler, S.R., Sheen, J., Rodriguez, P.L., and Zhu, J.-K. (2009). In vitro reconstitution of an abscisic acid signalling pathway. Nature 462,660-664.
Fujimoto, S.Y., Ohta, M., Usui, A., Shinshi, H., and Ohme-Takagi, M. (2000). Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Plant Cell 12,393-404.
Fujioka, S., Niu, J., Schmidt, C., Sclabas, G.M., Peng, B., Uwagawa, T., Li, Z., Evans, D.B., Abbruzzese, J.L., and Chiao, P.J. (2004). NF-κB and AP-1 connection:mechanism of NF-KB-Dependent regulation of AP-1 activity. Mol Cell Biol 24,7806-7819.
Gadjev, I., Vanderauwera, S., Gechev, T.S., Laloi, C., Minkov, I.N., Shulaev, V., Apel, K., lnze, D., Mittler, R., and Van Breusegem, F. (2006). Transcriptomic footprints disclose specificity of reactive oxygen species signaling in Arabidopsis. Plant Physiol 141, 436-445.
Gechev, T., Gadjev, I., Van Breusegem, F., Inze, D., Dukiandjiev, S., Toneva, V, and Minkov, I. (2002). Hydrogen peroxide protects tobacco from oxidative stress by inducing a set of antioxidant enzymes. Cell Mol Life Sci 59,708-714.
Gechev, T.S., Breusegem, F.V., Stone, J.M., Denev, I., and Laloi, C. (2006). Reactive oxygen species as signals that modulate plant stress responses and programmed cell death. BioEssays 28,1091-1101.
Gechev, T.S., and Hille, J. (2005). Hydrogen peroxide as a signal controlling plant programmed cell death. J Cell Biol 168,17-20.
Geiger, D., Scherzer, S., Mumm, P., Stange, A., Marten, I., Bauer, H., Ache, P., Matschi, S., Liese, A., Al-Rasheid, K.A.S., et al. (2009). Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair. Proc Natl Acad Sci 106,21425-21430.
Gelli, A., and Blumwald, E. (1997). Hyperpolarization-activated Ca2+-permeable channels in the plasma membrane of tomato cells. J Membrane Biol 155,35-45.
Geum, D., Son, G.H., and Kim, K. (2002). Phosphorylation-dependent cellular localization and thermoprotective role of heat shock protein 25 in Hippocampal Progenitor Cells. J Biol Chem 277,19913-19921.
Gibson, S.I. (2005). Control of plant development and gene expression by sugar signaling. Curr Opin Plant Biol 8,93-102.
Giraud, E., Ho, L.H.M., Clifton, R., Carroll, A., Estavillo, G., Tan, Y.-F., Howell, K.A., Ivanova, A., Pogson, B.J., Millar, A.H., et al. (2008). The absence of ALTERNATIVE OXIDASE1 a in Arabidopsis results in acute sensitivity to combined light and drought stress. Plant Physiol 147,595-610.
Goujon, T., Minic, Z., Amrani, A.E., Lerouxel, O., Aletti, E., Lapierre, C., Joseleau, J.-P., and Jouanin, L. (2003). AtBXL1 a novel higher plant (Arabidopsis thaliana) putative beta-xylosidase gene, is involved in secondary cell wall metabolism and plant development. Plant J 33,677-690.
Green, P.J., Kay, S.A., and Chua,N.H. (1987). Sequence-specific interactions of a pea nuclear factor with light-responsive elements upstream of the rbcS-3A gene. EMBO J 6,2543-2549.
Guan, L.M., Zhao, J., and Scandalios, J.G. (2000). Cis-elements and trans-factors that regulate expression of the maize Catl antioxidant gene in response to ABA and osmotic stress:H2O2 is the likely intermediary signaling molecule for the response. Plant J 22,87-95.
Gudesblat, G.E., Iusem, N.D., and Morris, P.C. (2007). Guard cell-specific inhibition of Arabidopsis MPK3 expression causes abnormal stomatal responses to abscisic acid and hydrogen peroxide. New Phytol 173,713-721.
Guiltinan, M., Marcotte, W., Jr, and Quatrano, R. (1990). A plant leucine zipper protein that recognizes an abscisic acid response element. Science 250,267-271.
Gutierrez, R., Lejay, L., Dean, A., Chiaromonte, F., Shasha, D., and Coruzzi, G. (2007). Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis. Genome Biol 8, R7.
Haake, V, Cook, D., Riechmann, J.L., Pineda, O., Thomashow, M.F., and Zhang, J.Z. (2002). Transcription factor CBF4 is a regulator of drought adaptation in Arabidopsis. Plant Physiol 130,639-648.
Hamilton, D.W.A., Hills, A., Kohler, B., and Blatt, M.R. (2000). Ca2+ channels at the plasma membrane of stomatal guard cells are activated by hyperpolarization and abscisic acid. Proc Natl Acad Sci 97,4967-4972.
Hancock, J.T., Henson, D., Nyirenda, M., Desikan, R., Harrison, J., Lewis, M., Hughes, J., and Neill, S.J. (2005). Proteomic identification of glvceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis. Plant Physiol Biochem 43,828-835.
Harding, S.A., Oh, S.H., and Roberts, D.M. (1997). Transgenic tobacco expressing a foreign calmodulin gene shows an enhanced production of active oxygen species. EMBO J 16,1137-1144.
Hattori, T., Totsuka, M., Hobo, T., Kagaya, Y., and Yamamoto-Toyoda, A. (2002). Experimentally determined sequence requirement of ACGT-containing abscisic acid response element. Plant Cell Physiol 43,136-140.
He, J.-X., Gendron, J.M., Sun, Y., Gampala, S.S.L., Gendron, N., Sun, C.Q., and Wang, Z.-Y. (2005a). BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses. Science 307,1634-1638.
He, J., Xu, H., She, X., Song, X., and Zhao, W. (2005b). The role and the interrelationship of hydrogen peroxide and nitric oxide in the UV-B-induced stomatal closure in broad bean. Funct Plant Biol 32,237-247.
He, R., Drury, GE., Rotari, V.I., Gordon, A., Willer, M., Farzaneh, T., Woltering, E.J., and Gallois, P. (2008). Metacaspase-8 modulates programmed cell death induced by ultraviolet light and H2O2 in Arabidopsis. J Biol Chem 283,774-783.
Herbig, A.F., and Helmann, J.D. (2001). Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA. Mol Microbiol 41,849-859.
Hicks, L.M., Cahoon, R.E., Bonner, E.R., Rivard, R.S., Sheffield, J., and Jez, J.M. (2007). Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thaliana. Plant Cell 19,2653-2661.
Hidalgo, E., and Demple, B. (1994). An iron-sulfur center essential for transcriptional activation by the redox-sensing SoxR protein. EMBO J 13,138-146.
Hideg, E., Barta, C., Kalai, T., Vass,I., Hideg, K., and Asada, K. (2002). Detection of singlet oxygen and superoxide with fluorescent sensors in leaves under stress by photoinhibition or UV radiation. Plant Cell Physiol 43,1154-1164.
Hideg, E., Kalai, T., Hideg, K., and Vass,I. (1998). Photoinhibition of photosynthesis in vivo results in singlet oxygen production detection via nitroxide-induced fluorescence quenching in broad bean leaves. Biochem 37,11405-11411.
Higo, K., and Higo, H. (1996). Cloning and characterization of the rice CatA catalase gene, a homologue of the maize Cat3 gene. Plant Mol Biol 30,505-521.
Himmelbach, A., Iten, M., and Grill, E. (1998). Signalling of abscisic acid to regulate plant growth. Philos T R Soc B:Biol Sci 353, 1439-1444.
Himmelbach, A., Yang, Y., and Grill, E. (2003). Relay and control of abscisic acid signaling. Curr Opin Plant Biol 6,470-479.
Hobo, T., Asada, M., Kowyama, Y, and Hattori, T. (1999). ACGT-containing abscisic acid response element (ABRE) and coupling element 3 (CE3) are functionally equivalent. Plant J 19,679-689.
Hong, Z., Jing, W., Utah, N., Randy, D.A., and Howard, M.G. (1997). Cloning and expression of an Arabidopsis gene encoding a putative peroxisomal ascorbate peroxidase. Plant Mol Biol 34,967-971.
Hord, C.L.H., Sun, Y.-J., Pillitteri, L.J., Torii, K.U., Wang, H., Zhang, S., and Ma, H, (2008). Regulation of Arabidopsis early anther development by the mitogen-activated protein kinases, MPK3 and MPK6, and the ERECTA and related receptor-like kinases. Mol Plant 1,645-658.
Hoth, S., Morgante, M., Sanchez, J.-P., Hanafey, M.K., Tingey, S.V., and Chua, N.-H. (2002). Genome-wide gene expression profiling in Arabidopsis thaliana reveals new targets of abscisic acid and largely impaired gene regulation in the abil-I mutant. J Cell Sci 115,4891-4900.
Huang, J., Sun, S.-J., Xu, D.-Q., Yang, X., Bao, Y.-M., Wang, Z.-F., Tang, H.-J., and Zhang, H. (2009a). Increased tolerance of rice to cold, drought and oxidative stresses mediated by the overexpression of a gene that encodes the zinc finger protein ZFP245. Biochem Biophys Res Commun 389,556-561.
Huang, X.-Y., Chao, D.-Y, Gao, J.-P., Zhu, M.-Z., Shi, M., and Lin, H.-X. (2009b). A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control. Genes Dev 23,1805-1817.
Ichimura, K., Casais, C., Peck, S.C., Shinozaki, K., and Shirasu, K. (2006). MEKK1 is required for MPK4 activation and regulates tissue-specific and temperature-dependent cell death in Arabidopsis. J Biol Chem 281,36969-36976.
Ikner, A., and Shiozaki, K. (2005). Yeast signaling pathways in the oxidative stress response. Mutat Res 569,13-27.
Imsande, J. (1999). Iron-sulfur clusters:Formation, perturbation, and physiological functions. Plant Physiol Biochem 37,87-97.
Islam, M.M., Munemasa, S., Hossain, M.A., Nakamura, Y, Mori, I.C., and Murata, Y. (2010). Roles of AtTPC1, vacuolar two pore channel 1, in Arabidopsis Stomatal Closure. Plant Cell Physiol 51,302-311.
Jammes, F., Song, C., Shin, D., Munemasa, S., Takeda, K., Gu, D., Cho, D., Lee, S., Giordo, R., Sritubtim, S., et al. (2009). MAP kinases MPK9 and MPK12 are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling. Proc Natl Acad Sci 106,20520-20525.
Jang, H.H., Lee, K.O., Chi, Y.H., Jung, B.G, Park, S.K., Park, J.H., Lee, J.R., Lee, S.S., Moon, J.C., and Yun, J.W. (2004). Two enzymes in one:two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function. Cell 117,625-635.
Jiang, Y, and Deyholos, M. (2009). Functional characterization of Arabidopsis NaCl-inducible WRKY25 and WRKY33 transcription factors in abiotic stresses. Plant Mol Biol 69,91-105.
Jin, H., Cominelli, E., Bailey, P., Parr, A., Mehrtens, F., Jones, J., Tonelli, C., Weisshaar, B., and Martin, C. (2000). Transcriptional repression by AtMYB4 controls production of UV-protecting sunscreens in Arabidopsis. EMBO J 19,6150-6161.
Jones, M.A., Raymond, M.J., Yang, Z., and Smirnoff, N. (2007). NADPH oxidase-dependent reactive oxygen species formation required for root hair growth depends on ROP GTPase. J Exp Bot 58,1261-1270.
Joo, J.H., Wang, S., Chen, J.G., Jones, A.M., and Fedoroff, N.V. (2005). Different signaling and cell death roles of heterotrimeric G Protein α and βsubunits in the Arabidopsis oxidative stress response to ozone. Plant Cell 17,957-970.
Kaffarnik, F., Muller, P., Leibundgut, M., Kahmann, R., and Feldbrugge, M. (2003). PKA and MAPK phosphorylation of Prfl allows promoter discrimination in Ustilago maydis. EMBO J 22,5817-5826.
Katiyar-Agarwal, S., Zhu, J., Kim, K., Agarwal, M., Fu, X., Huang, A., and Zhu, J.-K. (2006). Colloquium Paper:The plasma membrane Na+/H+ antiporter SOS1 interacts with RCD1 and functions in oxidative stress tolerance in Arabidopsis. Proc Natl Acad Sci 103,18816-18821.
Keller, T., Damude, H.G., Werner, D., Doerner, P., Dixon, R.A., and Lamb, C. (1998). A plant homolog of the neutrophil NADPH oxidase gp91phox subunit gene encodes a plasma membrane protein with Ca2+ binding motifs. Plant Cell 10,255-266.
Kenichi, H., and Hiromi, H. (1996). Cloning and characterization of the rice CatA catalase gene, a homologue of the maize Cat3 gene. Plant Mol Biol 30,505-521.
Kimura, M., Manabe, K., Abe, T., Yoshida, S., Matsui, M., and Yamamoto, Y.Y. (2003). Analysis of hydrogen peroxide-independent expression of the high-light-inducible ELIP2 Gene with the aid of the ELIP2 promoter-luciferase fusion. Photochem Photobiol 77,668-674.
Klusener, B., Young, J.J., Murata, Y., Allen, G.J., Mori, I.C., Hugouvieux, V., and Schroeder, J.I. (2002). Convergence of calcium signaling pathways of pathogenic elicitors and abscisic acid in Arabidopsis guard cells. Plant Physiol 130,2152-2163.
Kobayashi, M., Ohura, I., Kawakita, K., Yokota, N., Fujiwara, M., Shimamoto, K., Doke, N., and Yoshioka, H. (2007). Calcium-dependent protein kinases regulate the production of reactive oxygen species by potato NADPH oxidase. Plant Cell 19,1065-1080.
Kolla, V., Vavasseur, A., and Raghavendra, A. (2007). Hydrogen peroxide production is an early event during bicarbonate induced stomatal closure in abaxial epidermis of Arabidopsis. Planta 225,1421-1429.
Kosugi, S., Hasebe,M., Matsumura, N., Takashima, H., Miyamoto-Sato, E., Tomita, M., and Yanagawa, H. (2008). Six classes of nuclear localization signals specific to different binding grooves of importin a. J Biol Chem 284,478-485.
Koussevitzky, S., Nott, A., Mockler, T.C., Hong, F., Sachetto-Martins, G., Surpin, M., Lim, J., Mittler, R., and Chory, J. (2007). Signals from chloroplasts converge to regulate nuclear gene expression. Science 316,715-719.
Kovtun, Y., Chiu, W.L., Tena, G., and Sheen, J. (2000). Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants. Proc Natl Acad Sci 97,2940-2945.
Krawczyk, S., Thurow, C., Niggeweg, R., and Gatz, C. (2002). Analysis of the spacing between the two palindromes of activation sequence-1 with respect to binding to different TGA factors and transcriptional activation potential. Nucleic Acids Res 30, 775-781.
Kroj, T., Rudd, J.J., Nurriberger, T., Gabler, Y., Lee, J., and Scheel, D. (2003). Mitogen-activated protein kinases play an essential role in oxidative burst-independent expression of pathogenesis-related genes in parsley. J Biol Chem 278,2256-2264.
Krysan, P.J., Jester, P.J., Gottwald, J.R., and Sussman, M.R. (2002). An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis. THE Plant Cell 14,1109-1120.
Kuge, S., Jones, N., and Nomoto, A. (1997). Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16, 1710-1720.
Kurepa, J., Herouart, D., van Montagu, M., and lnze, D. (1997). Differential expression of CuZn-and Fe-superoxide dismutase genes of tobacco during development, oxidative stress, and hormonal treatments. Plant Cell Physiol 38,463-470.
Kwak, J.M., Mori, I.C., Pei, Z.M., Leonhardt, N., Torres, M.A., Dangl, J.L., Bloom, R:E., Bodde, S., Jones, J.D.G., and Schroeder, J.I. (2003). NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis. EMBO J 22,2623-2633.
Lu, D., Zhang, X., Jiang, J., An, G., Zhang, L., and Song, C.-P. (2005). NO may function in the downstream of H2O2 in ABA-induced stomatal closure in Vicia faba L. J Plant Physiol Mol Biol 31,62-70.
Lang, V, and Palva, E.T. (1992). The expression of a rab-related gene, rabl8, is induced by abscisic acid during the cold acclimation process of Arabidopsis thaliana (L.) Heynh. Plant Mol Biol 20,951-962.
Leon-Kloosterziel, K.M., Gil, M.A., Ruijs, G.J., Jacobsen, S.E., Olszewski, N.E., Schwartz, S.H., Zeevaart, J.A.D., and Koornneef, M. (1996). Isolation and characterization of abscisic acid-deficient Arabidopsis mutants at two new loci. Plant J 10,655-661.
la Cour, T., Kiemer, L., Molgaard, A., Gupta, R., Skriver, K., and Brunak, S. (2004). Analysis and prediction of leucine-rich nuclear export signals. Protein Eng Des Sel 17,527-536.
Laby, R.J., Kincaid, M.S., Kim, D., and Gibson, S.I. (2000). The Arabidopsis sugar-insensitive mutants sis4 and sis5 are defective in abscisic acid synthesis and response. Plant J 23,587-596.
Laloi, C., Apel, K., and Danon, A, (2004). Reactive oxygen signalling:the latest news. Curr Opin Plant Biol 7,323-328.
Laloi, C., Stachowiak, M., Pers-Kamczyc, E., Warzych, E., Murgia, I., and Apel, K. (2007). Cross-talk between singlet oxygen-and hydrogen peroxide-dependent signaling of stress responses in Arabidopsis thaliana. Proc Natl Acad Sci 104,672-677.
Lam, E., Kato, N., and Lawton, M. (2001). Programmed cell death, mitochondria and the plant hypersensitive response. Nature 411, 848-853.
Lamb, C., and Dixon, R.A. (1997). the oxidative burst in plant disease resistance. Annu Rev Plant Physiol Plant Mol Biol 48, 251-275.
Lee, J., Rudd, J.J., Macioszek, V.K., and Scheel, D. (2004). Dynamic changes in the localization of MAPK cascade components controlling pathogenesis-related (PR) gene expression during innate immunity in parsley. J Biol Chem 279,22440-22448.
Lee, J.W., and Helmann, J.D. (2006). The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation. Nature 440, 363-367.
Lee, Y.-H., and Chun, J.-Y. (1998). A new homeodomain-leucine zipper gene from Arabidopsis thaliana induced by water stress and abscisic acid treatment. Plant Mol Biol 37,377-384.
Lee, Y., Bak, G., Choi, Y, Chuang, W.-I., Cho, H.-T., and Lee, Y. (2008). Roles of phosphatidylinositol 3-kinase in root hair growth. Plant Physiol 147,624-635.
Leonhardt, N., Kwak, J.M., Robert, N., Waner, D., Leonhardt, G., and Schroeder, J.I. (2004). Microarray expression analyses of Arabidopsis guard cells and isolation of a recessive abscisic acid hypersensitive protein phosphatase 2C mutant. Plant Cell 16, 596-615.
Levine, A., Pennell, R.I., Alvarez, M.E., Palmer, R., and Lamb, C. (1996). Calcium-mediated apoptosis in a plant hypersensitive disease resistance response. Curr Biol 6, 427-437.
Li, C., Chen, Q., Gao, X., Qi, B., Chen, N., Xu, S., Chen, J., and Wang, X. (2005). AtHsfA2 modulates expression of stress responsive genes and enhances tolerance to heat and oxidative stress in Arabidopsis. Sci China C Life Sci 48,540-550.
Li, H.-B., Qin, Y.-M., Pang, Y., Song, W.-Q., Mei, W.-Q., and Zhu, Y.-X. (2007). A cotton ascorbate peroxidase is involved in hydrogen peroxide homeostasis during fibre cell development. New Phytol 175,462-471.
Li, J.-H., Liu, Y.-Q., Lu, P., Lin, H.-F., Bai, Y, Wang, X.-C., and Chen, Y.-L. (2009). A signaling pathway linking nitric oxide production to heterotrimeric G protein and hydrogen peroxide regulates extracellular calmodulin induction of stomatal closure in Arabidopsis. Plant Physiol 150,114-124.
Liang, H., Yao, N., Song, J.T., Luo, S., Lu, H., and Greenberg, J.T. (2003). Ceramides modulate programmed cell death in plants. Genes Dev 17,2636-2641.
Lin, J., Wang, Y, and Wang, G. (2006). Salt stress-induced programmed cell death in tobacco protoplasts is mediated by reactive oxygen species and mitochondrial permeability transition pore status. J Plant Physiol 163,731-739.
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., and Shinozaki, K. (1998). Two transcription factors, DREB1 and DREB2, with an EREBP/AP2 DNA binding domain separate two cellular signal transduction pathways in drought- and low-temperature-responsive gene expression, respectively, in Arabidopsis. Plant Cell 10,1391-1406.
Locato, V., Gadaleta, C., Gara, L.D., And Pinto, M.C.D. (2008). Production of reactive species and modulation of antioxidant network in response to heat shock:a critical balance for cell fate. Plant Cell Environ 31,1606-1619.
Locato, V., Pinto, M.C.d., and Gara, L.D. (2009). Different involvement of the mitochondrial, plastidial and cytosolic ascorbate glutathione redox enzymes in heat shock responses. Physiol Plant 135,296-306.
Lorenzo, O., Piqueras, R., Sanchez-Serrano, J.J., and Solano, R. (2003). Ethylene Response Factorl integrates signals from ethylene and jasmonate pathways in plant defense. Plant Cell 15,165-178.
Lum, H.K., Butt, Y.K.C., and Lo, S.C.L. (2002). Hydrogen Peroxide Induces a Rapid Production of Nitric Oxide in Mung Bean (Phaseolus aureus). Nitric Oxide 6,205-213.
Muller, J., Beck, M., Mettbach, U., Komis, G., Hause, G., Menzel, D., and Samaj, J. (2009). Arabidopsis MPK6 is involved in cell division plane control during early root development and localizes to pre-prophase band, phragmoplast, trans-Golgi network and plasma membrane. Plant J 61,234-248.
Ma, Y, Szostkiewicz,I., Korte, A., Moes, D., Yang, Y., Christmann, A., and Grill, E. (2009). Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science 324,1064-1068.
Magnani, E., Sjolander, K., and Hake, S. (2004). From endonucleases to transcription factors:evolution of the AP2 DNA binding domain in plants. Plant Cell 16,2265-2277.
Magome, H., Yamaguchi, S., Hanada, A., Kamiya, Y., and Oda, K. (2004). dwarf and delayed-flowering I, a novel Arabidopsis mutant deficient in gibberellin biosynthesis because of overexpression of a putative AP2 transcription factor. Plant J 37, 720-729.
Maleck, K., Levine, A., Eulgem, T., Morgan, A., Schmid, J., Lawton, K.A., Dangl, J.L., and Dietrich, R.A. (2000). The transcriptome of Arabidopsis thaliana during systemic acquired resistance. Nat Genet 26,403-410.
Marechal, E., Hiratsuka, K., Delgado, J., Nairn, A., Qin, J., Chait, B., and Chua, N.-H. (1999). Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation. Plant Mol Biol 40,373-386.
Maxwell, D.P., Wang, Y, and McIntosh, L. (1999). The alternative oxidase lowers mitochondrial reactive oxygen production in plant cells. Proc Natl Acad Sci 96,8271-8276.
Mazel, A., Leshem, Y, Tiwari, B.S., and Levine, A. (2004). Induction of salt and osmotic stress tolerance by overexpression of an intracellular vesicle trafficking protein AtRab7 (AtRabG3e). Plant Physiol 134,118-128.
McAinsh, M.R., Clayton, H., Mansfield, T.A., and Hetherington, A.M. (1996). Changes in stomatal behavior and guard cell cytosolic free calcium in response to oxidative stress. Plant Physiol Ⅲ,1031-1042.
Meskauskiene, R., Nater, M., Goslings, D., Kessler, F., op den Camp, R., and Apel, K. (2001). FLU:a negative regulator of chlorophyll biosynthesis in Arabidopsis thaliana. Proc Natl Acad Sci 98,12826-12831.
Meyer, A., Puhler, A., and Niehaus, K. (2001). The lipopolysaccharides of the phytopathogen Xanthomonas campestris pv. campestris induce an oxidative burst reaction in cell cultures of Nicotiana tabacum. Planta 213,214-222.
Miao, Y., Laun, T., Smykowski, A., and Zentgraf, U. (2007). Arabidopsis MEKK1 can take a short cut:it can directly interact with senescence-related WRKY53 transcription factor on the protein level and can bind to its promoter. Plant Mol Biol 65,63-76.
Miao, Y., Lv, D., Wang, P., Wang, X.-C., Chen, J., Miao, C., and Song, C.-P. (2006). An Arabidopsis glutathione peroxidase functions as both a redox transducer and a scavenger in abscisic acid and drought stress responses. Plant Cell 18,2749-2766.
Millar, J.B., Buck, V., and Wilkinson, M.G. (1995). Pypl and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast. Genes Dev 9,2117-2130.
Miller, G.A.D., and Mittler, R.O.N. (2006). Could heat shock transcription factors function as hydrogen peroxide sensors in plants? Ann Bot 98,279-288.
Mittler, R., Kim, Y, Song, L., Coutu, J., Coutu, A., Ciftci-Yilmaz, S., Lee, H., Stevenson, B., and Zhu, J.K. (2006). Gain- and loss-of-function mutations in Zat10 enhance. the tolerance of plants to abiotic stress. FEBS Lett 580,6537-6542.
Miyazono, K.-i., Miyakawa, T., Sawano, Y., Kubota, K., Kang, H.-J., Asano, A., Miyauchi, Y., Takahashi, M., Zhi, Y., Fujita, Y., et al. (2009). Structural basis of abscisic acid signalling. Nature 462,609-614.
Monshausen, G.B., Bibikova, T.N., Weisenseel, M.H., and Gilroy, S. (2009). Ca2+ regulates reactive oxygen species production and pH during mechanosensing in Arabidopsis roots. Plant Cell 21,2341-2356.
Moon, H., Lee, B., Choi, G., Shin, D., Prasad, D.T., Lee, O., Kwak, S.-S., Kim, D.H., Nam, J., Bahk, J., et al. (2003). NDP kinase 2 interacts with two oxidative stress-activated MAPKs to regulate cellular redox state and enhances multiple stress tolerance in transgenic plants. Proc Natl Acad Sci 100,358-363.
Mori, I.C., and Schroeder, J.I. (2004). Reactive Oxygen Species Activation of plant Ca2+ channels. a signaling mechanism in polar growth, hormone transduction, stress signaling, and hypothetically mechanotransduction. Plant Physiol 135,702-708.
Motoaki, S., Junko,I., Mari, N., Miki, F., Tokihiko, N., Taishi, U., Asako, K., Maiko, N., Akiko, E., Tetsuya, S., et al. (2002). Monitoring the expression pattern of around 7,000 Arabidopsis genes under ABA treatments using a full-length cDNA microarray. Funct Integrat Genomics 2,282-291.
Mou, Z., Fan, W., and Dong, X. (2003). lnducers of plant systemic acquired resistance regulate NPR1 function through redox changes. Cell 113,935-944.
Mura, A., Medda, R., Longu, S., Floris, G., Rinaldi, A.C., and Padiglia, A. (2005). A Ca2+/calmodulin-binding peroxidase from Euphorbia Latex:novel aspects of calcium-hydrogen peroxide cross-talk in the regulation of plant defenses. Biochem 44, 14120-14130.
Murata, Y., Pei, Z.M., Mori, I.C., and Schroeder, J. (2001). Abscisic acid activation of plasma membrane Ca2+ channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abil-1 and abi2-1 protein phosphatase 2C mutants. Plant Cell 13,2513-2523.
Murgia, I., Delledonne, M., and Soave, C. (2002). Nitric oxide mediates iron-induced ferritin accumulation in Arabidopsis. Plant J 30,521-528.
Murgia, I., Tarantino, D., Vannini, C., Bracale, M., Carravieri, S., and Soave, C. (2004). Arabidopsis thaliana plants overexpressing thylakoidal ascorbate peroxidase show increased resistance to paraquat-induced photooxidative stress and to nitric oxide-induced cell death. Plant J 38,940-953.
Mustilli, A.-C., Merlot, S., Vavasseur, A., Fenzi, F., and Giraudat, J. (2002). Arabidopsis OST1 protein kinase mediates the regulation of stomatal aperture by abscisic acid and acts upstream of reactive oxygen species production. Plant Cell 14, 3089-3099.
Nemeth, K., Salchert, K., Putnoky, P., Bhalerao, R., Koncz-Kalman, Z., Stankovic-Stangeland, B., Bako, L., Mathur, J., Okresz, L., Stabel, S., et al. (1998). Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis. Genes Dev 12,3059-3073.
Nakagami, H., Kiegerl, S., and Hirt, H. (2004).OMTK1, a novel MAPKKK, channels oxidative stress signaling through direct MAPK interaction. J Biol Chem 279,26959-26966.
Nakagami, H., Soukupova, H., Schikora, A., Zarsky, V, and Hirt, H. (2006). a mitogen-activated protein kinase kinase kinase mediates reactive oxygen species homeostasis in Arabidopsis. J Biol Chem 281,38697-38704.
Nakano, T., Suzuki, K., Fujimura, T., and Shinshi, H. (2006). Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol 140,411-432.
Neill, S., Desikan, R., and Hancock, J. (2002). Hydrogen peroxide signalling. Curr Opin Plant Biol 5,388-395.
Neill, S.J., Desikan, R., and Hancock, J.T. (2003). Nitric oxide signalling in plants. New Phytol 159,11-35.
Nguyen, A.N., Lee, A., Place, W., and Shiozaki, K. (2000). Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase. Mol Biol Cell 11,1169-1181.
Ning, J., Li, X., Hicks, L.M., and Xiong, L. (2010). A raf-like MAPKKK gene DSM1 mediates drought resistance through reactive oxygen species scavenging in rice. Plant Physiol 152,876-890.
Ogasawara, Y., Kaya, H., Hiraoka, G, Yumoto, F., Kimura, S., Kadota, Y, Hishinuma, H., Senzaki, E., Yamagoe, S., Nagata, K.,. et al. (2008). Synergistic activation of the Arabidopsis NADPH oxidase AtrbohD by Ca2+ and Phosphorylation. J Biol Chem 283, 8885-8892.
Olsson, A., Engstrom, P., and Soderman, E. (2004). The homeobox genes ATHB12 and ATHB7 encode potential regulators of growth in response to water deficit in Arabidopsis. Plant Mol Biol 55,663-677.
Onate-Sanchez, L., Anderson, J.P., Young, J., and Singh, K.B. (2007). AtERF14, a member of the erf family of transcription factors, plays a nonredundant role in plant defense. Plant Physiol 143,400-409.
op den Camp, R.G.L., Przybyla, D., Ochsenbein, C., Laloi, C., Kim, C., Danon, A., Wagner, D., Hideg, E., Gobel, C., Feussner,I., et al. (2003). Rapid induction of distinct stress responses after the release of singlet oxygen in Arabidopsis. Plant Cell 15, 2320-2332.
Orozco-Cardenas, M., and Ryan, C.A. (1999). Hydrogen peroxide is generated systemically in plant leaves by wounding and systemin via the octadecanoid pathway. Proc Natl Acad Sci 96,6553-6557.
Ortiz-Masia, D., Perez-Amador, M.A., Carbonell, J., and Marcote, M.J. (2007). Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis. FEBS Lett 581,1834-1840.
Palmieri, M.C., Sell, S., Huang, X., Scherf, M., Werner, T., Durner, J., and Lindermayr, C. (2008). Nitric oxide-responsive genes and promoters in Arabidopsis thaliana:a bioinformatics approach. J Exp Bot,59,117-186.
Panchuk, I.I., Volkov, R.A., and Schoffl, F. (2002). Heat stress- and heat shock transcription factor-dependent expression and activity of ascorbate peroxidase in Arabidopsis. Plant Physiol 129,838-853.
Pandey, G.K., Cheong, Y.H., Kim, K.N., Grant, J.J., Li, L., Hung, W., D'Angelo, C., Weinl, S., Kudla, J., and Luan, S. (2004). The calcium sensor calcineurin B-like 9 modulates abscisic acid sensitivity and biosynthesis in Arabidopsis. Plant Cell 16, 1912-1924.
Pandey, S., Nelson, D.C., and Assmann, S.M. (2009). Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis. Cell 136,136-148.
Pang, Q., Hays, J.B., and Rajagopal,1. (1993). Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E.coli mutants lacking recombination-intermediate-resolution activities. Nucleic Acids Res 21,1647-1653.
Park, J., Gu, Y., Lee, Y., Yang, Z., and Lee, Y. (2004). Phosphatidic acid induces leaf cell death in Arabidopsis by activating the Rho-related small G protein GTPase-mediated pathway of reactive oxygen species generation. Plant Physiol 134,129-136.
Park, K.-Y, Jung, J.-Y, Park, J., Hwang, J.-U., Kim, Y.-W., Hwang,I., and Lee, Y (2003). A role for phosphatidylinositol 3-phosphate in abscisic acid-induced reactive oxygen species generation in guard cells. Plant Physiol 132,92-98.
Park, S.-Y, Fung, P., Nishimura, N., Jensen, D.R., Fujii, H., Zhao, Y, Lumba, S., Santiago, J., Rodrigues, A., Chow, T.-f.F., et al. (2009). Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins. Science 324, 1068-1071.
Parker, J.E., Holub, E.B., Frost, L.N., Falk, A., Gunn, N.D., and Daniels, M.J. (1996). Characterization of edsl, a mutation in Arabidopsis suppressing resistance to Peronospora parasitica Specified by several different RPP genes. Plant Cell 8, 2033-2046.
Pavet, V, Olmos, E., Kiddle, G., Mowla, S., Kumar, S., Antoniw, J., Alvarez, M.E., and Foyer, C.H. (2005). Ascorbic acid deficiency activates cell death and disease resistance responses in Arabidopsis. Plant Physiol 139,1291-1303.
Pei, Z.-M., Murata, Y., Benning, G., Thomine, S., Klusener, B., Allen, G.J., Grill, E., and Schroeder, J.I. (2000). Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells. Nature 406,731-734.
Peltier, J.-B., Emanuelsson, O., Kalume, D.E., Ytterberg, J., Friso, G., Rudella, A., Liberles, D.A., Soderberg, L., Roepstorff, P., von Heijne, G, et al. (2002). Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction, plant cell 14,211-236.
Pieterse, C.M.J., and Van Loon, L.C. (2004). NPR1:the spider in the web of induced resistance signaling pathways. Curr Opin Plant Biol 7,456-464.
Pnueli, L., Liang, H., Rozenberg, M., and Mittler, R. (2003). Growth suppression, altered stomatal responses, and augmented induction of heat shock proteins in cytosolic ascorbate peroxidase (Apxl)-deficient Arabidopsis plants. Plant J 34,187-203.
Pomposiello, P.J., and Demple, B. (2001). Redox-operated genetic switches:the SoxR and OxyR transcription factors. Trends Biotech 19,109-114.
Popescu, S.C., Popescu, GV., Bachan, S., Zhang, Z., Gerstein, M., Snyder, M., and Dinesh-Kumar, S.P. (2009). MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Genes Dev 23,80-92.
Potocky, M., Jones, M.A., Bezvoda, R., Smirnoff, N., and Zarsky, V. (2007). Reactive oxygen species produced by NADPH oxidase are involved in pollen tube growth. New Phytol 174,742-751.
Price, A.H., Taylor, A., Ripley, S.J., Griffiths, A., Trewavas, A.J., and Knight, M.R. (1994). Oxidative signals in tobacco increase cytosolic calcium. Plant Cell 6,1301-1310.
Purvis, A.C. (1997). Role of the alternative oxidase in limiting superoxide production by plant mitochondria. Physiol Plant 100, 165-170.
Rashotte, A.M., DeLong, A., and Muday, GK. (2001). Genetic and chemical reductions in protein phosphatase activity alter auxin transport, gravity response, and lateral root growth. Plant Cell 13,1683-1697.
Ren, D., Liu, Y., Yang, K.-Y, Han, L., Mao, G, Glazebrook, J., and Zhang, S. (2008). A fungal-responsive MAPK cascade regulates phytoalexin biosynthesis in Arabidopsis. Proc Natl Acad Sci 105,5638-5643.
Ren, D., Yang, H., and Zhang, S. (2002). Cell death mediated by MAPK is associated with hydrogen peroxide production in Arabidopsis. J Biol Chem 277,559-565.
Rentel, M.C., and Knight, M.R. (2004). Oxidative stress-induced calcium signaling in Arabidopsis. Plant Physiol 135,1471-1479.
Rentel, M.C., Lecourieux, D., Ouaked, F., Usher, S.L., Petersen, L., Okamoto, H., Knight, H., Peck, S.C., Grierson, C.S., Hirt, H., et al. (2004). OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis. Nature 427,858-861.
Riechmann, J.L., Heard, J., Martin, G, Reuber, L., Z, C., Jiang, Keddie, J., Adam, L., Pineda, O., Ratcliffe, O.J., et al. (2000). Arabidopsis transcription factors:genome-wide comparative analysis among eukaryotes. Science 290,2105-2110.
Rizhsky, L., Davletova, S., Liang, H., and Mittler, R. (2004). The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis. J Biol Chem 279,11736-11743.
Rizhsky, L., Hallak-Herr, E., Van Breusegem, F., Rachmilevitch, S., Barr, J.E., Rodermel, S., Inze, D., and Mittler, R. (2002). Double antisense plants lacking ascorbate peroxidase and catalase are less sensitive to oxidative stress than single antisense plants lacking ascorbate peroxidase or catalase. Plant J 32,329-342.
Rizhsky, L., Liang, H., and Mittler, R. (2003). The water-water cycle is essential for chloroplast protection in the absence of stress. J Biol Chem 278,38921-38925.
Rook, F., Corke, F., Card, R., Munz, G, Smith, C., and Bevan, M.W. (2001). Impaired sucrose-induction mutants reveal the modulation of sugar-induced starch biosynthetic gene expression by abscisic acid signalling. Plant J 26,421-433.
Rossel, J.B., Wilson, P.B., Hussain, D., Woo, N.S., Gordon, M.J., Mewett, O.P., Howell, K.A., Whelan, J., Kazan, K., and Pogson, B.J. (2007). Systemic and Intracellular Responses to Photooxidative Stress in Arabidopsis. Plant Cell 19,4091-4110.
Rouse, D.T., Marotta, R., and Parish, R.W. (1996). Promoter and expression studies on an Arabidopsis thaliana dehydrin gene. FEBS Lett 381,252-256.
Rubinstein, B., and Luster, D.G (1993). Plasma membrane redox activity:components and role in plant processes. Annu Rev Plant Physiol Plant Mol Biol 44,131-155.
Ruelland, E., and Miginiac-Maslow, M. (1999). Regulation of chloroplast enzyme activities by thioredoxins:activation or relief from inhibition? Trends Plant Sci 4,136-141.
Salchert, K. (1998). Control of cell elongation and stress responses by steroid hormones and carbon catabolic repression in plants. Philos T R Soc B:Biol Sci 353,1517-1520.
Samadi, L., and Shahsavan Behboodi, B. (2006). Fusaric acid induces apoptosis in saffron root-tip cells:roles of caspase-like activity, cytochrome c, and H2O2. Planta 225,223-234.
Samuel, M.A., and Ellis, B.E. (2002). Double Jeopardy:Both overexpression and suppression of a redox-activated plant mitogen-activated protein kinase render tobacco plants ozone sensitive. Plant Cell 14,2059-2069.
Samuel, M.A., Hall, H., Krzymowska, M., Drzewiecka, K., Hennig, J., and Ellis, B.E. (2005). SIPK signaling controls multiple components of harpin-induced cell death in tobacco. Plant J 42,406-416.
Samuilov, V.D., Kiselevsky, D.B., Sinitsyn, S.V., Shestak, A.A., Lagunova, E.M., and Nesov, A.V. (2006). H2O2 intensifies CN--induced apoptosis in pea leaves. Biochem 71,384-394.
Scarpeci, T., Zanor, M., Carrillo, N., Mueller-Roeber, B., and Valle, E. (2008). Generation of superoxide anion in chloroplasts of Arabidopsis thaliana during active photosynthesis:a focus on rapidly induced genes. Plant Mol Biol 66,361-378.
Schindler, U., Beckmann, H., and Cashmore, A.R. (1992). TGA1 and g-box binding factors:two distinct classes of Arabidopsis leucine zipper proteins compete for the G-box-like element TGACGTGG Plant Cell 4,1309-1319.
Schopfer, P., Plachy, C., and Frahry, G (2001). Release of reactive oxygen intermediates (superoxide radicals, hydrogen peroxide, and hydroxyl radicals) and peroxidase in germinating radish seeds controlled by light, gibberellin, and abscisic acid. Plant Physiol 125,1591-1602.
Schreck, R., Rieber, P., and Baeuerle, P.A. (1991). Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J 10,2247-2258.
Schroeder, J.I., Kwak, J.M., and Allen, GJ. (2001). Guard cell abscisic acid signalling and engineering drought hardiness in plants. Nature 410,327-330.
Schubert, M., Petersson, U.A., Haas, B.J., Funk, C., Schroder, W.P., and Kieselbach, T. (2002). Proteome map of the chloroplast lumen of Arabidopsis thaliana. J Biol Chem 277,8354-8365.
Segal, A. W., and Abo, A. (1993). The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem Sci 18,43-47.
Sharma, Y.K., Leon, J., Raskin, I., and Davis, K.R. (1996). Ozone-induced responses in Arabidopsis thaliana:The role of salicylic acid in the accumulation of defense-related transcripts and induced resistance. Proc Natl Acad Sci 93,5099-5104.
Sharp, R.E., LeNoble, M.E., Else, M.A., Thorne, E.T., and Gherardi, F. (2000). Endogenous ABA maintains shoot growth in tomato independently of effects on plant water balance:evidence for an interaction with ethylene. J Exp Bot 51,1575-1584.
Sharrocks, A.D., Yang, S.-H., and Galanis, A. (2000). Docking domains and substrate-specificity determination for MAP kinases. Trends Biochem Sci 25,448-453.
She, X.-P., Song, X., and He, J. (2004). Role and relationship of nitric oxide and hydrogen peroxide in light/dark-regulated stomatal movement in Vicia faba. Acta botanica sinica 46,1292-1300.
Sheen, J., Zhou, L., and Jang, J.C. (1999). Sugars as signaling molecules. Curr Opin Plant Biol 2,410-418.
Shilo, S., Roy, S., Khanna, S., and Sen, C.K. (2008). Evidence for the involvement of mirna in redox regulated angiogenic response of human microvascular endothelial cells. Arterioscler Thromb Vasc Biol 28,471-477.
Shiozaki, K., and Russell, P. (1996). Conjugation, meiosis, and the osmotic stress response are regulated by Spcl kinase through Atfl transcription factor in fission yeast. Genes Dev 10,2276-2288.
Sirichandra, C., Gu, D., Hu, H.-C., Davanture, M., Lee, S., Djaoui, M., Valot, B., Zivy, M., Leung, J., Merlot, S., et al. (2009). Phosphorylation of the Arabidopsis AtrbohF NADPH oxidase by OST1 protein kinase. FEBS Lett 583,2982-2986.
Solano, R., Stepanova, A., Chao, Q., and Ecker, J.R. (1998). Nuclear events in ethylene signaling:a transcriptional cascade mediated by Ethylene-insensitive3 and ethylene-response-factorl. Genes Dev 12,3703-3714.
Soncin, F., Zhang, X., Chu, B., Wang, X., Asea, A., Ann Stevenson, M., Sacks, D.B., and Calderwood, S.K. (2003). Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2. Biochem Biophy Res Commun 303,700-706.
Song, C.-P., Agarwal, M., Ohta, M., Guo, Y., Halfter, U., Wang, P., and Zhu, J.-K. (2005). Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Plant Cell 17,2384-2396.
Sorger, P.K., and Pelham, H.R.B. (1988). Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation. Cell 54,855-864.
Spassieva, S.D., Markham, J.E., and Hille, J. (2002). The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death. Plant J 32,561-572.
Stanley, K.H., Yu, Y, Snesrud, E.C., Moy, L.P., Linford, L.D., Haas, B.J., Nierman, W.C., and Quackenbush, J. (2005). Transcriptional divergence of the duplicated oxidative stress-responsive genes in the Arabidopsis genome. Plant J 41,212-220.
Stimberg, P., van de Sande, K., and Leyser, H.M.O. (2002). MAX1 and MAX2 control shoot lateral branching in Arabidopsis. Development 129,1131-1141.
Stockinger, E.J., Gilmour, S.J., and Thomashow, M.F. (1997). Arabidopsis thaliana CBF1 encodes an AP2 domain-containing transcriptional activator that binds to the C-repeat/DRE, a cis-acting DNA regulatory element that stimulates transcription in response to low temperature and water deficit. Proc Natl Acad Sci 94,1035-1040.
Sugie, A., Naydenov, N., Mizuno, N., Nakamura, C., and Takumi, S. (2006). Overexpression of wheat alternative oxidase gene Waoxla alters respiration capacity and response to reactive oxygen species under low temperature in transgenic Arabidopsis. Genes Genet Syst 81,349-354.
Tada, Y, Mori, T., Shinogi, T., Yao, N., Takahashi, S., Betsuyaku, S., Sakamoto, M., Park, P., Nakayashiki, H., Tosa, Y, et al. (2004). Nitric oxide and reactive oxygen species do not elicit hypersensitive cell death but induce apoptosis in the adjacent cells during the defense response of Oat. Mol Plant-Microbe Interac 17,245-253.
Tada, Y, Spoel, S.H., Pajerowska-Mukhtar, K., Mou, Z., Song, J., Wang, C, Zuo, J., and Dong, X. (2008). Plant immunity requires conformational charges of NPR1 via S-nitrosylation and thioredoxins. Science 321,952-956.
Takahashi, S., Seki, M., Ishida, J., Satou, M., Sakurai, T., Narusaka, M., Kamiya, A., Nakajima, M., Enju, A., Akiyama, K., et al. (2004). Monitoring the expression profiles of genes induced by hyperosmotic, high salinity, and oxidative stress and abscisic acid treatment in Arabidopsis cell culture using a full-length cDNA microarray. Plant Mol Biol 56,29-55.
Takeda, S., Gapper, C., Kaya, H., Bell, E., Kuchitsu, K., and Dolan, L. (2008). Local positive feedback regulation determines cell shape in root hair cells. Science 319,1241-1244.
Tena, G, Asai, T., Chiu, W.L., and Sheen, J. (2001). Plant mitogen-activated protein kinase signaling cascades. Curr Opin Plant Biol 4,392-400.
Toledano, M.B., Delaunay, A., Monceau, L., and Tacnet, F. (2004). Microbial H2O2 sensors as archetypical redox signaling modules. Trends Biochem Sci 29,351-357.
Torres, M. (2003). Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 8,369-391.
Torres, M.A., Dangl, J.L., and Jones, J.D.G (2002). Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response. Proc Natl Acad Sci 99,517-522.
Torres, M.A., Onouchi, H., Hamada, S., Machida, C, Hammond-Kosack, K.E., and Jones, J.D.G (1998). Six Arabidopsis thaliana homologues of the human respiratory burst oxidase (gp91phox). Plant J 14,365-370.
Tsukamoto, S., Morita, S., Hirano, E., Yokoi, H., Masumura, T., and Tanaka, K. (2005). A Novel cis-element that is responsive to oxidative stress regulates three antioxidant defense genes in rice. Plant Physiol 137,317-327.
Ulker, B., and Somssich, I.E. (2004). WRKY transcription factors:from DNA binding towards biological function. Curr Opin Plant Biol 7,491-498.
Umbach, A.L., Fiorani, F., and Siedow, J.N. (2005). Characterization of transformed Arabidopsis with altered alternative oxidase levels and analysis of effects on reactive oxygen species in tissue. Plant Physiol 139,1806-1820.
Umezawa, T., Sugiyama, N., Mizoguchi, M., Hayashi, S., Myouga, F., Yamaguchi-Shinozaki, K., Ishihama, Y, Hirayama, T., and Shinozaki, K. (2009). Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis. Proc Natl Acad Sci 106,17588-17593.
Uno, Y, Furihata, T., Abe, H., Yoshida, R., Shinozaki, K., and Yamaguchi-Shinozaki, K. (2000). Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions. Proc Natl Acad Sci 97,11632-11637.
Vacca, R.A., de Pinto, M.C., Valenti, D., Passarella, S., Marra, E., and De Gara, L. (2004). Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco bright-yellow 2 cells. Plant Physiol 134,1100-1112.
Vahisalu, T., Kollist, H., Wang, Y.-F., Nishimura, N., Chan, W.-Y, Valerio, G., Lamminmaki, A., Brosche, M., Moldau, H., Desikan, R., et al. (2008). SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling. Nature 452, 487-491.
Vahisalu, T., Puzorjova, I., Brosche, M., Valk, E., Lepiku, M., Moldau, H., Pechter, P., Wang, Y.-S., Lindgren, O., Salojarvi, J., et al. (2010). Ozone-triggered rapid stomatal response involves the production of reactive oxygen species, and is controlled by SLAC1 and OSTI. Plant J 62,442-453.
Vandenabeele, S., Van Der Kelen, K., Dat, J., Gadjev, I., Boonefaes, T., Morsa, S., Rottiers, P., Slooten, L., Van Montagu, M., Zabeau, M., et al. (2003). A comprehensive analysis of hydrogen peroxide-induced gene expression in tobacco. Proc Natl Acad Sci 100,16113-16118.
Vandenabeele, S., Vanderauwera, S., Vuylsteke, M., Rombauts, S., Langebartels, C., Seidlitz, H.K., Zabeau, M., Van Montagu, M., Inze, D., and Van Breusegem, F. (2004). Catalase deficiency drastically affects gene expression induced by high light in Arabidopsis thaliana. Plant J 39,45-58.
Vanderauwera, S., Zimmermann, P., Rombauts, S., Vandenabeele, S., Langebartels, C., Gruissem, W., Inze, D., and Van Breusegem, F. (2005). Genome-wide analysis of hydrogen peroxide-regulated gene expression in arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis. Plant Physiol 139,806-821.
Vannini, C., Iriti, M., Bracale, M., Locatelli, F., Faoro, F., Croce, P., Pirona, R., Di Maro, A., Coraggio, I., and Genga, A. (2006). The ectopic expression of the rice Osmyb4 gene in Arabidopsis increases tolerance to abiotic, environmental and biotic stresses. Physiol Mol Plant Pathol 69,26-42.
Vivancos, A.P., Castillo, E.A., Biteau, B., Nicot, C., Ayte, J., Toledano, M.B., and Hidalgo, E. (2005). A cysteine-sulfinic acid in peroxiredoxin regulates H2O2-sensing by the antioxidant Papl pathway. Proc Natl Acad Scis 102,8875-8880.
Vogel, J., Zarka, D., Van Buskirk, H., Fowler, S., and Thomashow, M. (2005). Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis. Plant J 41,195-211.
Volkov, R., Panchuk, I., Mullineaux, P., and Schoffl, F. (2006). Heat stress-induced H2O2 is required for effective expression of heat shock genes in Arabidopsis. Plant Mol Biol 61,733-746.
Wagner, D., Przybyla, D., op den Camp, R., Kim, C., Landgraf, F., Lee, K.P., Wursch, M., Laloi, C., Nater, M., Hideg, E., et al. (2004). The genetic basis of singlet oxygen-induced stress responses of Arabidopsis thaliana. Science 306,1183-1185.
Wang, H., Liu, Y., Bruffett, K., Lee, J., Hause, G., Walker, J.C., and Zhang, S. (2008a). Haplo-insufficiency of MPK3 in MPK6 mutant background uncovers a novel function of these two MAPKs in Arabidopsis ovule development. Plant Cell 20,602-613.
Wang, P.-C., Du, Y.-Y, An, G.-Y., Zhou, Y, Miao, C., and Song, C.-P. (2006). analysis of global expression profiles of Arabidopsis genes under abscisic acid and H2O2 Applications. J Integrat Plant Biol 48,62-74.
Wang, P., and Song, C.-P. (2008). Guard-cell signalling for hydrogen peroxide and abscisic acid. New Phytol 178,703-718.
Wang, Q., Guan, Y, Wu, Y., Chen, H., Chen, F., and Chu, C. (2008b). Overexpression of a rice OsDREBIF gene increases salt, drought, and low temperature tolerance in both Arabidopsis and rice. Plant Molecular Biology 67,589-602.
Wasner, M., Haugwitz, U., Reinhard, W., Tschop, K., Spiesbach, K., Lorenz, J., Mossner, J., and Engeland, K. (2003). Three CCAAT-boxes and a single cell cycle genes homology region (CHR) are the major regulating sites for transcription from the human cyclin B2 promoter. Gene 312,225-237.
Whitbred, J.M., and Schuler, M.A. (2000). Molecular Characterization of CYP73A9 and CYP82A1 P450 genes involved in plant defense in pea. Plant Physiol 124,47-58.
Wisniewski, J.-P., Cornille, P., Agnel, J.-P., and Montillet, J.-L. (1999). The extensin multigene family responds differentially to superoxide or hydrogen peroxide in tomato cell cultures. FEBS Lett 447,264-268.
Wojtaszek, P. (1997). Oxidative burst:an early plant response to pathogen infection. Biochem J 322 (Pt 3),681-692.
Woo, H.R., Kim, J.H., Nam, H.G, and Lim, P.O. (2004). The delayed leaf senescence mutants of Arabidopsis, orel, ore3, and ore9 are tolerant to oxidative stress. Plant Cell Physiol 45,923-932.
Xing, Y., Jia, W., and Zhang, J. (2007). AtMEKl mediates stress-induced gene expression of CAT1 catalase by triggering H2O2 production in Arabidopsis. J Exp Bot 58,2969-2981.
Xing, Y, Jia, W., and Zhang, J. (2008). AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis. Plant J 54,440-451.
Yamaguchi-Shinozaki, K., and Shinozaki, K. (2005). Organization of cis-acting regulatory elements in osmotic-and cold-stress-responsive promoters. Trends Plant Sci 10,88-94.
Yan, C., Lee, L.H., and Davis, L. (1998). Crmlp mediates regulated nuclear export of a yeast AP-1-like transcription factor. EMBO J 17,7416-7429.
Yang, T., and Poovaiah, B.W. (2002). Hydrogen peroxide homeostasis:Activation of plant catalase by calcium/calmodulin. Proc Natl Acad Sci 99,4097-4102.
Yang, Z., Tian, L.,Latoszek-Green, M., Brown, D., and Wu, K. (2005). Arabidopsis ERF4 is a transcriptional repressor capable of modulating ethylene and abscisic acid responses. Plant Mol Biol 58,585-596.
Yin, P., Fan, H., Hao, Q., Yuan, X., Wu, D., Pang, Y., Yan, C., Li, W., Wang, J., and Yan, N. (2009). Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol 16,1230-1236.
Yoo, S.-D., Cho, Y.-H., Tena, G., Xiong, Y, and Sheen, J. (2008). Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling. Nature 451,789-795.
Yoshida, K., Terashima, I., and Noguchi, K. (2007). Up-regulation of mitochondrial alternative oxidase concomitant with chloroplast over-reduction by excess light. Plant Cell Physiol 48,606-614.
Yuasa, T., Ichimura, K., Mizoguchi, T., and Shinozaki, K. (2001). Oxidative Stress Activates ATMPK6, an Arabidopsis Homologue of MAP Kinase. Plant Cell Physiol 42,1012-1016.
Zhang, A., Jiang, M., Zhang, J., Ding, H., Xu, S., Hu, X., and Tan, M. (2007). Nitric oxide induced by hydrogen peroxide mediates abscisic acid-induced activation of the mitogen-activated protein kinase cascade involved in antioxidant defense in maize leaves. New Phytol 175,36-50.
Zhang, B., Chen, W., Foley, R.C., Buttner, M., and Singh, K.B. (1995). Interactions between distinct types of DNA binding proteins enhance binding to ocs element promoter sequences. Plant Cell 7,2241-2252.
Zhang, S., and Klessig, D.F. (2001). MAPK cascades in plant defense signaling. Trends Plant Sci 6,520-527.
Zhang, W., Ruan, J., Ho, T.-h.D., You, Y, Yu, T., and Quatrano, R.S. (2005). Cis-regulatory element based targeted gene finding: genome-wide identification of abscisic acid- and abiotic stress-responsive genes in Arabidopsis thaliana. Bioinformatics 21, 3074-3081.
Zhang, X., Dong, F.C., Gao, J.F., and Song, C.P. (2001a). Hydrogen peroxide-induced changes in intracellular pH of guard cells precede stomatal closure. Cell Res 11,37-43.
Zhang, X., Miao, Y.C., An, GY, Zhou, Y., Shangguan, Z.P., Gao, J.F., and Song, C.P. (2001b). K+ channels inhibited by hydrogen peroxide mediate abscisic acid signaling in Vicia guard cells. Cell Res 11,195-202.
Zhang, X., Zhang, L., Dong, F., Gao, J., Galbraith, D.W., and Song, C.P. (2001c). Hydrogen peroxide is involved in abscisic acid-induced stomatal closure in Vicia faba. Plant Physiol 126,1438-1448.
Zhao, J., Zhang, W., Zhao, Y, Gong, X., Guo, L., Zhu, G, Wang, X., Gong, Z., Schumaker, K.S., and Guo, Y. (2007). SAD2, an importin-like protein, is required for UV-B response in Arabidopsis by mediating MYB4 nuclear trafficking. Plant Cell 19, 3805-3818.
Zheng, M., Aring, slund, F., and Storz, G.(1998). Activation of the OxyR transcription factor by reversible disulfide bond formation. Science 279,1718-1722.
Zheng, Z., Mosher, S., Fan, B., Klessig, D., and Chen, Z. (2007). Functional analysis of Arabidopsis WRKY25 transcription factor in plant defense against Pseudomonas syringae. BMC Plant Biol 7,2.
Zhou, D.-X. (1999). Regulatory mechanism of plant gene transcription by GT-elements and GT-factors. Trends Plant Sci 4,210-214.
Zhou, L., Jang, J.-c., Jones, T.L., and Sheen, J. (1998). Glucose and ethylene signal transduction crosstalk revealed by an Arabidopsis glucose-insensitive mutant. Proc Natl Acad Sci 95,10294-10299.