2018年安徽省14个市水源与出厂水中多种四环素类抗生素检测结果
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摘要
目的了解2018年安徽省14个地市饮用水系统中抗生素污染状况,调查14个地市主要自来水厂水源水与出厂水中四环素类抗生素(Tetracyclines,TCs)含量。方法于2018年丰水期(6月)采集安徽省14个市主要水厂水源水和出厂水共28份,利用固相萃取-高效液相色谱串联质谱同位素内标法分析11种TCs含量水平。结果 14个地市水源水、出厂水中除差向土霉素和氯四环素未检出外,其余9种污染物均检出,水源水和出厂水浓度范围分别为ND～1.46 ng/L、ND～0.82 ng/L。检出率较高的为强力霉素和金霉素,浓度在TCs中构成比为45.9%～100.0%。TCs检出浓度、检出种类和检出率呈现水源水>出厂水,淮河以北地区明显高于其他地区,江河水源地与地下水源地相当,高于水库水源地。结论 2018年安徽省14个地市水源水和出厂水不同程度受到TCs污染,仅为痕量水平。强力霉素和金霉素为主要污染物。
[Objective]To understand the status of antibiotic contamination in drinking water system of 14 cities from Anhui Province in 2018,investigate the tetracyclines(TCs) in the source water and finished water of the major water works in 14 cities.[Methods]Totally 28 source water samples and finished water samples were collected from 14 cities of Anhui Province during wet(June) seasons in 2018. Solid phase extraction-high performance liquid chromatography tandem mass spectrometry(HPLC/MS/MS) and isotope internal standard method were applied to analyse the contents of 11 TCs. [Results]In the whole water samples,9 kinds of TCs were pos itive,the other 2 kinds were negative(differential oxytetracycline and chlorotetracycline). The concentration ranges of source water and finished water were ND-1.46 ng/L and ND-0.82 ng/L,respectively. Doxycycline and chlortetracycline were highly detected,with a 45.9%-100.0% composition ratio in total TCs. The detection concentration,types and rate of TCs showed following characteristics: source water > finished water; area in the north of Huaihe River > other areas; the source of rivers water was similar to the groundwater,and both higher than the reservoir water. [Conclusion]The source water and finished water of 14 cities from Anhui Province in 2018 are polluted by TCs in different degrees,but only in a trace level.Doxycycline and chlortetracycline are the main pollutants.
[Objective]To understand the status of antibiotic contamination in drinking water system of 14 cities from Anhui Province in 2018,investigate the tetracyclines(TCs) in the source water and finished water of the major water works in 14 cities.[Methods]Totally 28 source water samples and finished water samples were collected from 14 cities of Anhui Province during wet(June) seasons in 2018. Solid phase extraction-high performance liquid chromatography tandem mass spectrometry(HPLC/MS/MS) and isotope internal standard method were applied to analyse the contents of 11 TCs. [Results]In the whole water samples,9 kinds of TCs were pos itive,the other 2 kinds were negative(differential oxytetracycline and chlorotetracycline). The concentration ranges of source water and finished water were ND-1.46 ng/L and ND-0.82 ng/L,respectively. Doxycycline and chlortetracycline were highly detected,with a 45.9%-100.0% composition ratio in total TCs. The detection concentration,types and rate of TCs showed following characteristics: source water > finished water; area in the north of Huaihe River > other areas; the source of rivers water was similar to the groundwater,and both higher than the reservoir water. [Conclusion]The source water and finished water of 14 cities from Anhui Province in 2018 are polluted by TCs in different degrees,but only in a trace level.Doxycycline and chlortetracycline are the main pollutants.
引文
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[15]王军淋,许娇娇,蔡增轩,等.固相萃取富集-超高效液相色谱-串联质谱法同时测定源水和自来水中的40种多类别抗生素[J].中国卫生检验杂志,2016,(17):2443-2449.
[16]武旭跃,邹华,朱荣,等.太湖贡湖湾水域抗生素污染特征分析与生态风险评价[J].环境科学,2016,37(12):4596-4604.
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[20]张娣.磁性纳米Fe3O4去除水环境中抗生素类物质的研究[D].西安:西北农林科技大学,2011.
[2]CARVALHO I T,SANTOS L.Antibiotics in the aquatic environments:A review of the European scenario[J/OL].Environ Int,2016,94:736-757.[2018-10-01].https://www.sciencedirect.com/science/article/pii/S0160412016302434.DOI:10.1016/j.envint.2016.06.025.
[3]RI CHARDSON BJ,LAM PK,MARTIN M.Emerging chemicals of concern:pharmaceuticals and personal care products(PPCPs)in Asia,with particular reference to Southern China[J].Mar Pollut Bull,2005,50(9):913.
[4]HUANG CH,RENEW JE,SMEBY KL,et al.Assessment of potential antibiotic contaminants in water and preliminary occurrence analysis[J].J Contemp Wat Res Ed,2001,120(1):30-40.
[5]张新波,宋姿,张丹,等.天津供水系统中抗生素分布变化特征与健康风险评价[J].环境科学,2018,39(1):99-108.
[6]LIU JL,WONG MH.Pharmaceuticals and personal care products(PPCPs):A review on environmental contamination in China[J].Environ Int,2013,59(3):208-224.
[7]那广水.中国北方地区水体中四环素族抗生素残留现状分析[J].中国环境监测,2009,25(6):2.
[8]张练,吴维,李楠,等.供水管网中抗生素污染研究[J].中国给水排水,2017(11):39-43.
[9]TANG J,SHI T,WU X,et al.The occurrence and distribution of antibiotics in Lake Chaohu,China:Seasonal variation,potential source and risk assessment[J/OL].Chemosphere,2015,122:154-161.[2018-10-01].https://www.sciencedirect.com/science/article/pii/S0045653514013502.DOI:10.1016/j.chemosphere.2014.11.032.
[10]ZHANG H,LI X,YANG Q,et al.Plant Growth,Antibiotic Uptake,and Prevalence of Antibiotic Resistance in an Endophytic System of Pakchoi under Antibiotic Exposur e[J].Int J Env Res Pub He,2017,14(11):1336.
[11]韦善学.妊娠期与哺乳期合理用药分析[J].中国现代药物应用,2014,8(10):119-120.
[12]中华人民共和国卫生部,中国国家标准化管理委员会.生活饮用水标准检测方法:GB/T 5750-2006[S].北京:中国标准出版社,2007:3.
[13]YAO L,WANG Y,TONG L,et al.Seasonal variation of antibiotics concentration in the aquatic environment:a case study at Jianghan Plain,central China[J].Sci Total Environ,2015,527-528(8):56-64.
[14]JIANG L,HU X,YIN D,et al.Occurrence,distribution and seasonal variation of antibiotics in the Huangpu River,Shanghai,China[J].Chemosphere,2011,82(6):822-828.
[15]王军淋,许娇娇,蔡增轩,等.固相萃取富集-超高效液相色谱-串联质谱法同时测定源水和自来水中的40种多类别抗生素[J].中国卫生检验杂志,2016,(17):2443-2449.
[16]武旭跃,邹华,朱荣,等.太湖贡湖湾水域抗生素污染特征分析与生态风险评价[J].环境科学,2016,37(12):4596-4604.
[17]VERMA B,HEADLEY JV,Robarts RD.Behaviour and fate of tetracycline in river and wetland waters on the Canadian Northern Great Plains[J].Environ Lett,2007,42(2):109-117.
[18]CHOI KJ,KIM SG,KIM CW,et al.Determination of antibiotic compounds in water by on-line SPE-LC/MSD[J].Chemosphere,2007,66(6):977-984.
[19]FIG UEROA RA,LEONARD A,MACKAY AA.Modeling tetracycline antibiotic sorption to clays[J].Environ Sci Technol,2004,38(2):476-483.
[20]张娣.磁性纳米Fe3O4去除水环境中抗生素类物质的研究[D].西安:西北农林科技大学,2011.