合成生物学的知识伦理问题初探

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英文篇名：A Preliminary Research on the Problem of the Ethics of Knowledge of Synthetic Biology 作者：雷瑞鹏 ; 冀朋 英文作者：LEI Ruipeng;JI Peng;Department of Philosophy,School of Humanities,Huazhong University of Science and Technology; 关键词：合成生物学 ; 知识伦理 ; 知识滥用 ; 责任区分 英文关键词：Synthetic biology;;The ethics of knowledge;;Abuse of knowledge;;Responsibility distinction 中文刊名：自然辩证法通讯 英文刊名：Journal of Dialectics of Nature 机构：中科技大学人文学院哲学系; 出版日期：2019-01-31 出版单位：自然辩证法通讯 年：2019 期：02 基金：国家社科基金重大项目“高科技伦理问题研究”(项目编号:12&ZD117)子课题“合成生物学伦理问题研究”成果之一 语种：中文; 页：105-111 页数：7 CN：11-1518/N ISSN：1000-0763 分类号：Q81

摘要

合成生物学和所有高技术一样面临"两用困境":是造福人类,还是滥用知识而危害人类?这是生命伦理学家对合成生物学发展最关注的问题。因此,发展"知识伦理"来探究合成生物学知识的产生和使用、科学工作面临的责任与规范以及如何制定有效的关于知识错误传播与滥用的减少风险战略显得极为重要。通过伦理分析,我们认为,针对知识滥用需要适度的伦理管制,对科学家在知识错误传播和滥用的问题上需要仔细区分责任,而知识的内在价值与使用价值也不能完全剥离,而是应该在追求知识的真理性的同时造福人类并规避风险。
        Synthetic biology faces the same "dual-use dilemma" as all high technologies: is it to benefit mankind or to abuse knowledge and harm mankind? This is the most important concern of bioethicists on the development of synthetic biology.Therefore, it is very important to develop an "ethics of knowledge" to explore the generation and use of synthetic biological knowledge, the responsibilities and norms faced by scientific work, and how to formulate effective reductions in the dissemination and abuse of knowledge.Through ethical analysis, we believe that the abuse of knowledge requires moderate ethical regulation, and the scientists need to carefully distinguish responsibility from the problem of misinformation and misuse of knowledge.Simultaneously, the intrinsic value and use value of knowledge cannot be completely divested. Instead, we should avoid risks and benefit mankind while pursuing the truth of knowledge.

引文

[1]贾斌、李炳志、元英进.合成生物学展望[J].中国科学,2014,9(44):1455-1460.
    [2]Daniel,Y.G.R.'Ethical Theory for“Dual-Use”Dilemmas in Synthetic Biology'[J].Asian Bioethics Review,2012,4(2):150-159.
    [3]More,M.,Vita-More,N.The Proactionary Principle[M].New York:John Wiley&Sons,2013,258-267.
    [4]Douglas,T.,Savulescu,J.'Synthetic Biology and the Ethics of Knowledge'[J].Journal of Medical Ethics,2010,36(11):687-693.
    [5]Kitney,R.I.'Synthetic Biology:Scope,Applications and Implications'[R].London:The Royal Academy of Engineering,2009,9-11.
    [6]马延和.生物炼制细胞工厂:生物制造的技术核心[J].生物工程学报,2010,26(10):1321-1326.
    [7]Lupas,A.N.What I Cannot Create,I Do Not Understand[J].Science,2014,346(6216):1455-1456.
    [8]孙明伟、李寅、高福.从人类基因组到人造生命:克雷格·文特尔领路生命科学[J].生物工程学报,2010,26(6):697-706.
    [9]OSTP.'United States Government Policy for Oversight of Life Sciences Dual-Use Research of Concern'[EB/OL].http://connection.ebscohost.com/c/articles/86933539/united-states-government-policy-institutional-oversightlife-sciences-dual-use-research-concern.2013-05-26.
    [10]Link,H.J.'Playing God and the Intrinsic Value of Life:Moral Problems for Synthetic Biology?'[J].Science&Engineering Ethics,2013,19(2):435-448.
    [11]尼采.快乐的科学[M].黄明嘉译,上海:华东师范大学出版社,2007,209.
    [12]Cello,J.,Paul,A.V.,Wimmer,E.'Chemical Synthesis of Poliovirus cDNA:Generation of Infections Virus in the Absence of Natural Template'[J].Science,2002,297(5583):1016-1018.
    [13]Kobasa,D.,Takada,A.,Shinya,K.,et al.'Enhanced Virulence of Influenza A Viruses With the Haemagglutinin of the 1918 Pandemic Virus'[J].Nature,2004,431(7009):703-707.
    [14]Xiao,M.F.,Zhang,B.Z.,Liu,C.L.'Synthetic Biology in Studying the Origin of Life,Evolution,and Structurefunction Relation'[J].Scientia Sinica Vitae,2015,45(10):915-927.
    [15]刘虹、任元鹏.论定义生命与生命定义[J].医学与哲学,2011,32(1):8-10.
    [16]Mayr,E.The Grouth of Biological Thought[M].Cambridge:Harvard University Press,1982,53.
    [17]Gibson,D.G.,Venter,J.C.'Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome'[J].Science,2010,329(5987):52-56.
    [18]Percival,R.V.'Who's Afraid of the Precautionary Principle'[J].Pace Environmental Law Review,2006,23(1):21-81.
    [19]梁慧刚、黄翠、宋冬林等.合成生物学研究和应用的生物安全问题[J].科技导报,2016,34(2):307-312.