转录因子DREB、ERF和NAC在介导植物响应生物和非生物胁迫中的作用
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摘要
生物和非生物胁迫是影响植物生长和造成农业减产的重要原因.近年来,已经鉴定了几个可以调控胁迫相关基因表达的转录因子.这些转录因子在控制植物生物系统转录重编程中起重要作用,能提高植物对生物和非生物胁迫的耐受能力.因此,识别和表征与植物胁迫反应有关的关键基因对增强转基因植物的胁迫耐受能力是必不可少的.本文介绍了DREB、ERF和NAC转录因子,重点介绍其在转基因植物增强对生物和非生物胁迫耐受性的潜力.
The adverse effects of biotic and abiotic stresses are major factors which affect plant growth and reduce agricultural yield.In recent years,several transcription factors had been identified that could regulate the expression of stress-related genes.These transcription factors played a crucial role in controlling transcriptional reprogramming in the development of plant biological systems,and also enhanced the biotic and abiotic tolerance of plants.Therefore,it is essential to identify and characterize the key genes involved in plant stress responses to enhance the stress tolerance of transgenic plants.DREB,ERF and NAC transcription factors have been introduced with emphasis on their potential to enhance the tolerance of transgenic plants to biotic and abiotic stresses in genetic engineering.
The adverse effects of biotic and abiotic stresses are major factors which affect plant growth and reduce agricultural yield.In recent years,several transcription factors had been identified that could regulate the expression of stress-related genes.These transcription factors played a crucial role in controlling transcriptional reprogramming in the development of plant biological systems,and also enhanced the biotic and abiotic tolerance of plants.Therefore,it is essential to identify and characterize the key genes involved in plant stress responses to enhance the stress tolerance of transgenic plants.DREB,ERF and NAC transcription factors have been introduced with emphasis on their potential to enhance the tolerance of transgenic plants to biotic and abiotic stresses in genetic engineering.
引文
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[3] Montesinos E.Antimicrobial peptides and plant diseasecontrol[J].FEMS Microbiol Lett,2007,270:1-11.
[4] Mittler R,Blumwald E.Genetic engineering for modern agriculture:challenges and perspectives[J].Annu Rev Plant Biol,2020,61:443-462.
[5] Hernandez-Garcia C M,Finer J J.Identification and validationof promoters and cis-acting regulatory elements[J].Plant Sci,2014,217-218:109-119.
[6] Mitsuda N,Ohme-Takagi M.Functional analysis of transcriptionfactors in Arabidopsis[J].Plant Cell Physiol,2009,50:1 232-1 248.
[7] Buscaill P,Rivas S.Transcriptional control of plant defence responses[J].Curr Opin Plant Biol,2014,20:35-46.
[8] Kilian J,Peschke F,Berendzen K W,et al.Prerequisites,performance and profits of transcriptional profiling theabiotic stress response[J].BBA-Gene Regul Mech,2012,1 819:166-175.
[9] Pandey P,Ramegowda V,Senthil-Kumar M.Shared and uniqueresponses of plants to multiple individual stresses and stresscombinations:physiological and molecularmechanisms[J].Front Plant Sci,2015,6:723.
[10] Humphrey T V,Bonetta D T,Goring D R.Sentinels at the wall:cell wall receptors and sensors[J].New Phytol,2007,176:7-21.
[11] Munnik T,Vermeer J E M.Osmotic stress-induced phosphoinositideand inositol phosphate signalling in plants[J].Plant Cell Environ,2010,33:655-659.
[12] Eyidogan F,Oz M T,Yucel M,et al.Signal transductionof phytohormones under abiotic stresses[J].Phytohorm AbioticStress Toler Plants,2012,642:978-1 007.
[13] Wurzinger B,Mair A,Pfister B,et al.Cross-talk of calcium dependent protein kinase and MAP kinase signaling[J].Plant Signal Behav,2011,6:8-12.
[14] Samad A F A,Sajad M,Nazaruddin N,et al.Micro RNA and transcription factor:key playersin plant regulatory network[J].Front Plant Sci,2017,8:565.
[15] Sakuma Y,Liu Q,Dubouzet J G,et al.DNA-binding specificity of the ERF/AP2domain of Arabidopsis DREBs,transcription factors involvedin dehydration-and cold-inducible gene expression[J].Biochem Biophys Res Commun,2002,290:998-1 009.
[16] Agarwal M,Hao Y,Kapoor A,et al.A R2R3 type MYB transcription factor is involved in thecold regulation of CBF genes and in acquired freezing tolerance[J].J Biol Chem,2006,281:37 636-37 645.
[17] Dubouzet J G,Sakuma Y,Ito Y,et al.OsDREB genes in rice,Oryza sativa L.,encode transcription activatorsthat function in drought,high-salt-and cold responsive geneexpression[J].Plant J,2003,33:751-763.
[18] Kudo K,Oi T,Uno Y.Functional characterization and expressionprofiling of a DREB2-type Gene from lettuce (Lactucasativa L.)[J].Plant Cell Tissue Organ Cult,2014,116:97-109.
[19] Li X,Zhang D,Li H,et al.EsDREB2B,a novel truncated DREB2-type transcription factor in the desertlegume Eremospartonsongoricum,enhances tolerance to multipleabiotic stresses in yeast and transgenic tobacco[J].BMC Plant Biol,2014,14:44.
[20] Kume S,Kobayashi F,Ishibashi M,et al.Differential and coordinated expression of Cbf and Cor/Lea genes during long-term cold acclimation in two wheat cultivarsshowing distinct levels of freezing tolerance[J].Genes Genet Syst,2005,80:185-197.
[21] Yang T,Zhang L,Zhang T,et al.Transcriptionalregulation network of cold-responsive genes in higherplants[J].Plant Sci,2005,169:987-995.
[22] Chinnusamy V,Ohta M,Kanrar S,et al.ICE1:a regulator of cold-induced transcriptome andfreezing tolerance in Arabidopsis[J].Gene Dev,2003,17:1 043-1 054.
[23] Dong C H,Agarwal M,Zhang Y,et al.The negativeregulator of plant cold responses,HOS1,is a RING E3 ligase thatmediates the ubiquitination and degradation of ICE1[J].Proc Natl Acad Sci USA,2006,103:8 281-8 286.
[24] Shi H,Chan Z.The cysteine2/histidine2-type transcriptionfactor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activatedC-REPEAT-BINDING FACTOR pathway is essential formelatonin-mediated freezing stress resistance in Arabidopsis[J].J Pineal Res,2014,57:185-191.
[25] Nakamichi N,Kusano M,Fukushima A,et al.Transcript profiling ofan Arabidopsis PSEUDO RESPONSE REGULATOR arrhythmictriple mutant reveals a role for the circadian clock in coldstress response[J].Plant Cell Physiol,2009,50:447-462.
[26] Jin W M,Dong J,Hu Y L,et al.Improvedcold-resistant performance in transgenic grape (Vitisvinifera L.)overexpressing cold inducible transcription factors AtDREB1b[J].Hortscience,2009,44:35-39.
[27] Owens C L,Thomashow M F,Hancock J F,et al.CBF1 orthologs in sour cherry and strawberry and the heterologousexpression of CBF1 in strawberry[J].J Am SocHorticSci,2002,127:489-494.
[28] Savitch L V,Allard G,Seki M,et al.The effect of overexpression of twoBrassica CBF/DREB1-like transcription factors on photosyntheticcapacity and freezing tolerance in Brassica napus[J].Plant Cell Physiol,2005,46:1 525-1 539.
[29] Zhao J,Ren W,Zhi D,et al.Arabidopsis DREB1A/CBF3 bestowed transgenic tall fescue increased tolerance todrought stress[J].Plant Cell Rep,2007,26:1 521-1 528.
[30] Qin F,Sakuma Y,Li J,et al.Cloning and functional analysis of a novelDREB1/CBF transcription factor involved in cold-responsivegene expression in Zea mays L[J].Plant Cell Physiol,2004,45:1 042-1 052.
[31] Zhang X,Fowler S G,Cheng H,et al.Freezing-sensitive tomato has afunctional CBF cold response pathway,but a CBF regulonthat differs from that of freezing-tolerant Arabidopsis[J].Plant J,2004,39:905-919.
[32] Yang W,Liu X D,Chi X J,et al.Dwarf apple MbDREB1 enhancesplant tolerance to low temperature,drought,and salt stress viaboth ABA-dependent and ABA-independent pathways[J].Planta,2011,233:219-229.
[33] Sakuma Y,Maruyama K,Qin F,et al.Dual function of anArabidopsis transcriptionfactor DREB2A in water-stress-responsive and heat stress-responsive gene expression[J].Proc Natl Acad Sci USA,2006,103:18 822-18 827.
[34] Qin F,Sakuma Y,Tran L S,et al.Arabidopsis DREB2A interacting proteins function as RING E3 ligases and negativelyregulate plant drought stress-responsive gene expression[J].Plant Cell,2008,20:1 693-1 707.
[35] Kim J S,Mizoi J,Kidokoro S,et al.Arabidopsis growth-regulating factor 7 functions as a transcriptionalrepressor of abscisic acid and osmotic stress-responsivegenes,including DREB2A[J].Plant Cell,2012,24:3 393-3 405.
[36] Schramm F,Larkindale J,Kiehlmann E,et al.A cascade of transcriptionfactor DREB2A and heat stress transcription factor HsfA3 regulatesthe heat stress response of Arabidopsis[J].Plant J,2008,53:264-274.
[37] Qin F,Kakimoto M,Sakuma Y,et al.Regulation andfunctional analysis of ZmDREB2A in response to drought andheat stresses in Zea mays L[J].Plant J,2007,50:54-69.
[38] Cui M,Zhang W,Zhang Q,et al.Inducedover-expression of the transcription factor OsDREB2A improvesdrought tolerance in rice[J].Plant Physiol Biochem,2011,49:1 384-1 391.
[39] Chen J Q,Meng X P,Zhang Y,et al.Over-expressionof OsDREB genes lead to enhanced drought tolerance inrice[J].Biotechnol Lett,2008,30:2 191-2 198.
[40] Zhang X X,Tang Y J,Ma Q B,et al.OsDREB2A,a rice transcription factor,significantlyaffects salt tolerance in transgenic soybean[J].PLoS ONE,2013,8:e83 011.
[41] Chen M,Wang Q Y,Cheng X G,et al.GmDREB2,a soybean DRE-binding transcription factor,conferred drought and high-salt tolerance in transgenic plants[J].Biochem Biophys Res Commun,2007,353:299-305.
[42] Agarwal P,Agarwal P K,Joshi A J,et al.Overexpression of PgDREB2A transcription factor enhances abioticstress tolerance and activates downstream stress-responsivegenes[J].Mol Biol Rep,2010,37:1 125-1 135.
[43] Morran S,Eini O,Pyvovarenko T,et al.Improvementof stress tolerance of wheat and barley by modulation of expressionof DREB/CBF factors[J].Plant Biotechnol J,2011,9:230-249.
[44] Chen H,Liu L,Wang L,et al.VrDREB2A,aDREB-binding transcription factor from Vignaradiata,increaseddrought and high-salt tolerance in transgenic Arabidopsis thaliana[J].J Plant Res,2016,129:1-11.
[45] Arroyo-Herrera A,Figueroa-Yáňez L,Castaňo E,et al.A novel Dreb2-type gene from Carica papaya confers tolerance under abiotic stress[J].Plant CellTissue Organ Cult,2016,125:119-133.
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