Graphene Sculpturene Nanopores for DNA Nucleobase Sensing

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• 作者：Hatef Sadeghi ; L. Algaragholy ; T. Pope ; S. Bailey ; D. Visontai ; D. Manrique ; J. Ferrer ; V. Garcia-Suarez ; Sara Sangtarash ; Colin J. Lambert
• 刊名：Journal of Physical Chemistry B
• 出版年：2014
• 出版时间：June 19, 2014
• 年：2014
• 卷：118
• 期：24
• 页码：6908-6914
• 全文大小：473K
• 年卷期：v.118,no.24(June 19, 2014)
• ISSN：1520-5207

文摘

To demonstrate the potential of nanopores in bilayer graphene for DNA sequencing, we computed the current鈥搗oltage characteristics of a bilayer graphene junction containing a nanopore and found that they change significantly when nucleobases are transported through the pore. To demonstrate the sensitivity and selectivity of example devices, we computed the probability distribution P_X(尾) of the quantity 尾 representing the change in the logarithmic current through the pore due to the presence of a nucleobase X (X = adenine, thymine, guanine, or cytosine). We quantified the selectivity of the bilayer-graphene nanopores by showing that P_X(尾) exhibits distinct peaks for each base X. To demonstrate that such discriminating sensing is a general feature of bilayer nanopores, the well-separated positions of these peaks were shown to be present for different pores, with alternative examples of electrical contacts.