Total Synthesis of (卤)-未-Rubromycin

详细信息    查看全文

• 作者：Wenjing Wang ; Jijun Xue ; Tian Tian ; Jie Zhang ; Liping Wei ; Jidong Shao ; Zhixiang Xie ; Ying Li
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：May 17, 2013
• 年：2013
• 卷：15
• 期：10
• 页码：2402-2405
• 全文大小：323K
• 年卷期：v.15,no.10(May 17, 2013)
• ISSN：1523-7052

文摘

Transition-metal-catalyzed spiroketalization cyclization has been performed successfully and has led to the first total synthesis of (卤)-未-rubromycin with a longest linear sequence of 18 steps from commercially available guaiacol in a 2.7% overall yield.