Decreased muscarinic M1 receptor gene expression in the cerebral cortex of streptozotocin-induced diabetic rats and Aegle marmelose leaf extract's therapeutic function

详细信息	查看全文 | 推荐本文 |

• 作者：Gangadharan Gireesh ; S. Khan Reas ; Mathew Jobin ; Cheramadathikudiyil Skaria Paulose
• 关键词：Muscarinic receptors ; Cerebral cortex ; Streptozotocin ; Aegle marmelose ; Diabetes
• 刊名：Journal of Ethnopharmacology
• 出版年：2008
• 期刊代码：26_03788741
• 类别：pha
• 出版时间：5 March 2008
• 卷：116
• 期：2
• 页码：296-304
• 文件大小：465 K

摘要

In the present study we have investigated the changes in the total muscarinic and muscarinic M1 receptor ([³H]QNB) binding and gene expression in the cerebral cortex of streptozotocin (STZ) induced diabetic, insulin and aqueous extract of Aegle marmelose leaf treated diabetic rats.