A case of severe oral self-injurious Tourette's syndrome alleviated by pregabalin

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• 作者：Michele Fornaro ; M.D.^a ; ^{dott.fornaro@gmail.com} ; Angelo Giovanni Icro Maremmani ; M.D.^b ; ^{angelogicro@gmail.com} ; Maria Giovanna Colicchio ; M.D.^c ; ^{cmgiovanna22@gmail.com} ; Anna Romano ; M.D.^b ; ^{annaromano21@libero.it} ; Stefania Fornaro ; M.D.^d ; ^{stefaniafornaro1981@gmail.com} ; Salvatore Rizzato ; M.D.^b ; ^{salvatore_rizzato@libero.it} ; Giovanni Ciampa ; M.D.^b ; ^{ciampagiovanni1@gmail.com} ; Salvatore Colicchio ; M.D.^e ; ^{salvatorecolicchio.md@gmail.com} ; Liliana Dell'Osso ; M.D.^b ; ^{ldelloss@med.unipi.it}
• 关键词：Tourette's syndrome ; Self-injury ; Pregabalin
• 刊名：General Hospital Psychiatry
• 出版年：2012
• 期刊代码：107_01638343
• 类别：med
• 出版时间：May-June, 2012
• 卷：34
• 期：3
• 页码：321.e1-321.e4
• 文件大小：322 K

摘要

Self-injurious behavior (SIB) associated with Tourette's syndrome (TS) is a severe neuropsychiatric condition that causes significant distress and can impair social functioning. The current treatment options for the condition include pharmacological, physical and psychosocial interventions. However, given the need for more effective interventions, especially for those patients who are unresponsive and/or intolerant to standard medications, further exploration of novel treatments is imperative. In this report, we present a case of SIB-TS that was successfully treated with pregabalin. The patient received 1-year of follow-up and was noted to have considerable improvement in symptoms. Although rigorous controlled studies are required, based on our case study, pregabalin may be a potential treatment option in some cases of SIB with TS.