US-FNAC检测甲状腺结节伴钙化患者的病理阳性率、血流信号及与甲状腺癌病理特征的相关性研究
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摘要
目的:探讨US-FNAC检测甲状腺结节伴钙化患者的病理阳性率、血流信号及与甲状腺癌病理特征的相关性。方法:选取2015年10月-2017年10月在本院接受手术治疗的甲状腺结节患者100例(结节109个),患者均接受US-FNAC检查,统计分析患者钙化情况、病理阳性率、局部血流信号情况及甲状腺癌病理特征。结果:本研究结节良性69个,恶性40个,微小钙化型结节恶性率均显著高于其他三种钙化类型(P<0.05),+++级血流信号强度结节恶性率均显著高于其他三种血流信号(P<0.05);微小钙化的存在与患者甲状腺包膜侵犯、淋巴结转移和结节直径有关(P<0.05)。结论:US-FNAC检测可以结合结节钙化类型与血流信号预测结节病理阳性率,且结节钙化与甲状腺癌病理特征有关。
Objective:To explore the correlation between pathological positive rate,blood flow signal and pathological features of thyroid carcinoma in patients with thyroid nodules and calcification detected by US-FNAC.Method:A total of 100 patients (109 nodules) with thyroid nodules underwent surgical treatment in our hospital from October 2015 to October 2017 were selected,they were examined by US-FNAC.The calcification,positive rate of pathology,local blood flow signal and pathological features of thyroid carcinoma were analyzed.Result:There were 69 benign nodules and 40 malignant nodules.The malignant rates of microcalcified nodules were significantly higher than those of the other three calcifications (P<0.05).The malignant rate of blood flow signal intensity of +++ level were significantly higher than those of the other three blood flow signals (P<0.05).The presence of microcalcification was associated with thyroid capsule invasion,lymph node metastasis and nodal diameter(P<0.05).Conclusion:US-FNAC can predict the positive rate of nodule pathology by combining nodule calcification type and blood flow signal,and nodule calcification is related to the pathological characteristics of thyroid carcinoma.
Objective:To explore the correlation between pathological positive rate,blood flow signal and pathological features of thyroid carcinoma in patients with thyroid nodules and calcification detected by US-FNAC.Method:A total of 100 patients (109 nodules) with thyroid nodules underwent surgical treatment in our hospital from October 2015 to October 2017 were selected,they were examined by US-FNAC.The calcification,positive rate of pathology,local blood flow signal and pathological features of thyroid carcinoma were analyzed.Result:There were 69 benign nodules and 40 malignant nodules.The malignant rates of microcalcified nodules were significantly higher than those of the other three calcifications (P<0.05).The malignant rate of blood flow signal intensity of +++ level were significantly higher than those of the other three blood flow signals (P<0.05).The presence of microcalcification was associated with thyroid capsule invasion,lymph node metastasis and nodal diameter(P<0.05).Conclusion:US-FNAC can predict the positive rate of nodule pathology by combining nodule calcification type and blood flow signal,and nodule calcification is related to the pathological characteristics of thyroid carcinoma.
引文
[1]黎丹凤,张进安.甲状腺结节与甲状腺癌的临床评估和处理[J].上海医药,2016,37(20):3-7.
[2]Peng Y,Zhou W,Zhan W W,et al.Ultrasonographic Assessment of Differential Diagnosis Between Degenerating Cystic Thyroid Nodules and Papillary Thyroid Microcarcinomas[J].World JSurg,2017,41(10):2538-2544.
[3]马慧娟,杨敬春.超声弹性成像对甲状腺良恶性结节鉴别诊断的研究进展[J].中国全科医学,2015,18(11):1307-1310.
[4]Lyle M A,Dean D S.Ultrasound-guided fine-needle aspiration biopsy of thyroid nodules in patients taking novel oral anticoagulants[J].Thyroid,2015,25(4):373-376.
[5]Kim Y H,Kwon H J,Kim E K,et al.Applying UltrasoundGuided Core Needle Biopsy for Diagnosis of Thyroid Masses:Preliminary Results From a Single Institution[J].J Ultrasound Med,2015,34(10):1801-1808.
[6]张平,王志宏,贺亮,等.超声探测甲状腺结节钙化的临床诊断价值[J].中国普通外科杂志,2014,23(5):657-660.
[7]王季圆.甲状腺结节钙化在超声诊断甲状腺癌中的价值[J].中国实用医药,2015,10(20):108-109.
[8]曾理,张保荣.超声引导下甲状腺结节细针穿刺细胞学检查与超声评估的临床价值[J].中国医疗设备,2017,32(S2):129-130.
[9]杨英,魏枫,薛晔霞.甲状腺结节细针穿刺细胞学检查与TI-RADS的价值分析[J/OL].中华临床医师杂志(电子版),2016,10(17):2547-2551.
[10]Samulski T D,Shutty C,LiVolsi V A,et al.The reliability of thyroid nodule ultrasound features and size to predict malignancy in fine needle aspiration specimens:Practical utility for the evaluating pathologist[J].Diagn Cytopathol,2015,43(6):471-477.
[11]张博,苏俊平,白杨,等.甲状腺结节合并微钙化与甲状腺癌关系及其危险因素分析[J].现代医学,2015,43(2):214-217.
[12]宋海英,黄道中,王菁.钙化与甲状腺癌关系的再认识[J/OL].中华医学超声杂志(电子版),2014,11(7):593-597.
[13]陈晨,甲状腺癌与甲状腺良性结节的多普勒超声对比分析[J].中国实用医药,2016,11(10):84-85.
[14]唐海玲,杨卓文,刘千琪,等.微细血流成像技术在甲状腺良恶性结节鉴别中的价值[J].中国超声医学杂志,2016,32(7):580-582.
[15]王博,刘珺,张玄娥,等.糖代谢异常与甲状腺结节相关性研究[J].中国全科医学,2015,18(30):3648-3652.
[16]Kong J,Li J C,Wang H Y,et al.Role of Superb MicroVascular Imaging in the Preoperative Evaluation of Thyroid Nodules:Comparison With Power Doppler Flow Imaging[J].J Ultrasound Med,2017,36(7):1329-1337.
[17]吴英龙,瞿茹莼.彩色多普勒及高频超声对甲状腺结节良、恶性鉴别的临床价值探究[J].影像研究与医学应用,2017,1(5):87-88.
[18]蒋晶,黄斌.不同分型钙化在甲状腺结节超声诊断中应用价值研究[J].中国现代医生,2016,54(30):96-99.
[19]陈晶,原韶玲,徐恩伟,等.误诊为甲状腺癌的甲状腺良性结节的声像图特征与病理表现[J/OL].中华医学超声杂志(电子版),2015,12(5):413-418.
[20]王帅,徐辉雄,徐军妹,等.甲状腺结节微钙化、粗大钙化及环状钙化与甲状腺癌的相关性分析[J].影像诊断与介入放射学,2015,24(3):212-215.
[2]Peng Y,Zhou W,Zhan W W,et al.Ultrasonographic Assessment of Differential Diagnosis Between Degenerating Cystic Thyroid Nodules and Papillary Thyroid Microcarcinomas[J].World JSurg,2017,41(10):2538-2544.
[3]马慧娟,杨敬春.超声弹性成像对甲状腺良恶性结节鉴别诊断的研究进展[J].中国全科医学,2015,18(11):1307-1310.
[4]Lyle M A,Dean D S.Ultrasound-guided fine-needle aspiration biopsy of thyroid nodules in patients taking novel oral anticoagulants[J].Thyroid,2015,25(4):373-376.
[5]Kim Y H,Kwon H J,Kim E K,et al.Applying UltrasoundGuided Core Needle Biopsy for Diagnosis of Thyroid Masses:Preliminary Results From a Single Institution[J].J Ultrasound Med,2015,34(10):1801-1808.
[6]张平,王志宏,贺亮,等.超声探测甲状腺结节钙化的临床诊断价值[J].中国普通外科杂志,2014,23(5):657-660.
[7]王季圆.甲状腺结节钙化在超声诊断甲状腺癌中的价值[J].中国实用医药,2015,10(20):108-109.
[8]曾理,张保荣.超声引导下甲状腺结节细针穿刺细胞学检查与超声评估的临床价值[J].中国医疗设备,2017,32(S2):129-130.
[9]杨英,魏枫,薛晔霞.甲状腺结节细针穿刺细胞学检查与TI-RADS的价值分析[J/OL].中华临床医师杂志(电子版),2016,10(17):2547-2551.
[10]Samulski T D,Shutty C,LiVolsi V A,et al.The reliability of thyroid nodule ultrasound features and size to predict malignancy in fine needle aspiration specimens:Practical utility for the evaluating pathologist[J].Diagn Cytopathol,2015,43(6):471-477.
[11]张博,苏俊平,白杨,等.甲状腺结节合并微钙化与甲状腺癌关系及其危险因素分析[J].现代医学,2015,43(2):214-217.
[12]宋海英,黄道中,王菁.钙化与甲状腺癌关系的再认识[J/OL].中华医学超声杂志(电子版),2014,11(7):593-597.
[13]陈晨,甲状腺癌与甲状腺良性结节的多普勒超声对比分析[J].中国实用医药,2016,11(10):84-85.
[14]唐海玲,杨卓文,刘千琪,等.微细血流成像技术在甲状腺良恶性结节鉴别中的价值[J].中国超声医学杂志,2016,32(7):580-582.
[15]王博,刘珺,张玄娥,等.糖代谢异常与甲状腺结节相关性研究[J].中国全科医学,2015,18(30):3648-3652.
[16]Kong J,Li J C,Wang H Y,et al.Role of Superb MicroVascular Imaging in the Preoperative Evaluation of Thyroid Nodules:Comparison With Power Doppler Flow Imaging[J].J Ultrasound Med,2017,36(7):1329-1337.
[17]吴英龙,瞿茹莼.彩色多普勒及高频超声对甲状腺结节良、恶性鉴别的临床价值探究[J].影像研究与医学应用,2017,1(5):87-88.
[18]蒋晶,黄斌.不同分型钙化在甲状腺结节超声诊断中应用价值研究[J].中国现代医生,2016,54(30):96-99.
[19]陈晶,原韶玲,徐恩伟,等.误诊为甲状腺癌的甲状腺良性结节的声像图特征与病理表现[J/OL].中华医学超声杂志(电子版),2015,12(5):413-418.
[20]王帅,徐辉雄,徐军妹,等.甲状腺结节微钙化、粗大钙化及环状钙化与甲状腺癌的相关性分析[J].影像诊断与介入放射学,2015,24(3):212-215.
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