耳穴压丸联合生脉胶囊改善维持性血液透析患者生活质量的临床研究
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摘要
目的观察耳穴压丸联合生脉胶囊改善维持性血液透析患者生活质量的临床疗效。方法选取2014年3月—2015年12月北京市东直门医院维持性血液透析(MHD)患者46例、第一中西医结合医院MHD患者26例,合计72例,通过随机分组方式将患者分为1、2组,进行前后交叉对照试验。试验分2个阶段进行,第一阶段1组为治疗组、2组为对照组;第二阶段2组为治疗组、1组为对照组。每一阶段均包括8周的治疗期和8周的随访期,完成第一阶段的治疗后,2组均经过4周的洗脱期,再交叉进行第二阶段为期8周的治疗,整个研究过程持续时间为20周。治疗组在常规血液透析的基础上,辅助耳穴压丸联合口服生脉胶囊治疗,对照组仅采用常规血液透析治疗。研究以SF-36评分量表评定患者的生活质量,观察耳穴压丸联合生脉胶囊是否改善血液透析患者生活质量,以及在生理机能(PF)、精力(VT)、健康变化(HT)三个方面的具体体现。结果 72例患者经过2个疗程的治疗后,治疗组患者的生理机能(PF)、精力(VT)、健康变化(HT)评分显著高于对照组(P<0.05),而2组的精神健康(MH)、社会功能(SF)、一般健康状况(GH)、躯体疼痛(BP)、生理职能(RP)、情感职能(RE)评分差异无统计学意义(P>0.05)。结论耳穴压丸联合生脉胶囊能在一定程度上改善维持性血液透析患者生活质量,体现在三方面:生理机能、精力、健康变化。
Objective To observe the clinical effect of auricular acupoint sticking and Shengmai capsules for improving quality of life in patients with maintenance Hemodialysis. Methods 72 patients with maintenance hemodialysis(MHD) were randomly divided into two groups(group one and group two) on average. All of these subjects were selected from Dongzhimen hospital from March 2014 to December 2015. Cross comparison before and after the study was applied. There were two stages in this research. In the first phase,group one was treatment group and group two was the control group. In the second phase, group two was the treatment group, while group one was the control group. Each stage consisted of 8 weeks of treatment period and 8 weeks of following-up. Both groups had a 4-week of washout period after first stage. Then each group switched interventions during the second stage for 8 weeks. The whole research process lasted for 20 weeks. Treatment group received regular hemodialysis, auxiliary earpills combined Shengmai capsules treatment, the control group only received hemodialysis treatment. The Short Form 36 Health Questionnaire(SF-36) was used to assess quality of life of patients to estimate whether uricular acupoint sticking and Shengmai capsules improved quality of life in patients receiving hemodialysis. The improvement embodied concretely in three dimensions(physiological function(PF), energy change(VT), health(HT)). Results After 2 phases of treatment, PF, VT and HT scores of treatment group patients were significantly higher than that of control group(P<0.05). While mental health(MH), social function(SF), general health(GH), body pain(BP),physiological functions(RP) and the functions of emotion(RE) score of both groups had no significant difference( P >0.05).Conclusion Auricular acupoint sticking and Shengmai capsules to a certain extent improve quality of life in patients with maintenance hemodialysis in three aspects: PF, VT and HT.
Objective To observe the clinical effect of auricular acupoint sticking and Shengmai capsules for improving quality of life in patients with maintenance Hemodialysis. Methods 72 patients with maintenance hemodialysis(MHD) were randomly divided into two groups(group one and group two) on average. All of these subjects were selected from Dongzhimen hospital from March 2014 to December 2015. Cross comparison before and after the study was applied. There were two stages in this research. In the first phase,group one was treatment group and group two was the control group. In the second phase, group two was the treatment group, while group one was the control group. Each stage consisted of 8 weeks of treatment period and 8 weeks of following-up. Both groups had a 4-week of washout period after first stage. Then each group switched interventions during the second stage for 8 weeks. The whole research process lasted for 20 weeks. Treatment group received regular hemodialysis, auxiliary earpills combined Shengmai capsules treatment, the control group only received hemodialysis treatment. The Short Form 36 Health Questionnaire(SF-36) was used to assess quality of life of patients to estimate whether uricular acupoint sticking and Shengmai capsules improved quality of life in patients receiving hemodialysis. The improvement embodied concretely in three dimensions(physiological function(PF), energy change(VT), health(HT)). Results After 2 phases of treatment, PF, VT and HT scores of treatment group patients were significantly higher than that of control group(P<0.05). While mental health(MH), social function(SF), general health(GH), body pain(BP),physiological functions(RP) and the functions of emotion(RE) score of both groups had no significant difference( P >0.05).Conclusion Auricular acupoint sticking and Shengmai capsules to a certain extent improve quality of life in patients with maintenance hemodialysis in three aspects: PF, VT and HT.
引文
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[5]刘李晗.耳针(迷走神经刺激)调节胃肠运动的功效及其与迷走神经的关系[D].南京:南京医科大学,2013:52.
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[8]邹生燕.辨证护理结合耳穴贴压治疗中风恢复期心脾两虚型失眠临床观察[J].中国临床医生,2012,40(8):55-57.
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[10]Zhang XX,Zhang LF,Liu MJ.Effectofsolution-focusedapproachcombined with auricular acupressure on anxiety and pain of patients.with postmenopausal cervical cancer during afterloading brachytherapy[J].Chin JNurs,2013,19(34):4232-4235.
[11]何静,张俐,袁发焕.血液透析患者生活质量的影响因素分析[J].重庆医学,2008,37(2):144-146.
[12]罗玲,雷延兰.心理干预对尿毒症患者血液透析期护理的效果研究[J].重庆医学,2013,42(5):593-594.
[13]马地那.生脉胶囊联合耳穴疗法治疗透析相关性低血压的临床研究[D].北京:北京中医药大学,2015.
[14]刘福生,钟剑,王玫,等.生脉胶囊联合艾灸治疗透析相关低血压的临床研究[J].北京中医药大学学报(中医临床版),2013,20(5):17-20.
[15]李春辉,曹钋,钟剑,等.耳穴压丸联合生脉胶囊改善血液透析患者瘙痒程度的临床研究[J].现代中医临床,2018,25(1):1-7.
[16]Lopes A A,Albert J M,Young E W,et al.creening for depression in hemodialysis patients:Associations with diagnosis,treatment,and outcomes in the DOPPS[J].Kidney Int,2004,66:2047-2048.
[17]秦洁,赵红,汪彬,等.血液透析患者生活质量及其影响因素的调查[J].解放军护理杂志,2010,27(3):185-187.
[18]李涵,曹钋,钟剑,等.耳穴压丸法对维持性血液透析患者焦虑状态的影响[J].中国当代医药,2017,24(8):150-153,163.
[19]曹丽杰,孙特,曹雷,等.维持性血液透析患者心理因素分析及心理干预.吉林大学学报(医学版),2013,39(2):382.
[2]Barsevick A M,Whitmer K,Nail L M,et al.Symptom clusters research:conceptual,design,measurement,and analysis issue[J].J Pain Symptom Manage,2006,31(1):85-95.
[3]王海燕,郑法雷,刘玉春,等.原发性肾小球疾病分型与治疗及诊断标准[J].中华内科杂志,1993,32(2):132.
[4]梁建丽.维持性血液透析患者生活质量测评及影响因素研究现状[J].内科,2013,8(2):191-193.
[5]刘李晗.耳针(迷走神经刺激)调节胃肠运动的功效及其与迷走神经的关系[D].南京:南京医科大学,2013:52.
[6]方继良.电针耳迷走神经治疗抑郁症临床观察及其机理的f MRI脑功能成像研究[D].北京:中国中医科学院,2013:115.
[7]李明宪.耳穴贴压治疗单纯肥胖症的作用及机理研究[D].广州:广州中医药大学,2012.
[8]邹生燕.辨证护理结合耳穴贴压治疗中风恢复期心脾两虚型失眠临床观察[J].中国临床医生,2012,40(8):55-57.
[9]吴秀清,钟志聪,周敏,等.耳穴贴压法干预维持性血液透析患者睡眠障碍的疗效[J].中国老年学杂志,2013,33(1):24-26.
[10]Zhang XX,Zhang LF,Liu MJ.Effectofsolution-focusedapproachcombined with auricular acupressure on anxiety and pain of patients.with postmenopausal cervical cancer during afterloading brachytherapy[J].Chin JNurs,2013,19(34):4232-4235.
[11]何静,张俐,袁发焕.血液透析患者生活质量的影响因素分析[J].重庆医学,2008,37(2):144-146.
[12]罗玲,雷延兰.心理干预对尿毒症患者血液透析期护理的效果研究[J].重庆医学,2013,42(5):593-594.
[13]马地那.生脉胶囊联合耳穴疗法治疗透析相关性低血压的临床研究[D].北京:北京中医药大学,2015.
[14]刘福生,钟剑,王玫,等.生脉胶囊联合艾灸治疗透析相关低血压的临床研究[J].北京中医药大学学报(中医临床版),2013,20(5):17-20.
[15]李春辉,曹钋,钟剑,等.耳穴压丸联合生脉胶囊改善血液透析患者瘙痒程度的临床研究[J].现代中医临床,2018,25(1):1-7.
[16]Lopes A A,Albert J M,Young E W,et al.creening for depression in hemodialysis patients:Associations with diagnosis,treatment,and outcomes in the DOPPS[J].Kidney Int,2004,66:2047-2048.
[17]秦洁,赵红,汪彬,等.血液透析患者生活质量及其影响因素的调查[J].解放军护理杂志,2010,27(3):185-187.
[18]李涵,曹钋,钟剑,等.耳穴压丸法对维持性血液透析患者焦虑状态的影响[J].中国当代医药,2017,24(8):150-153,163.
[19]曹丽杰,孙特,曹雷,等.维持性血液透析患者心理因素分析及心理干预.吉林大学学报(医学版),2013,39(2):382.
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