他汀类药物在临床应用中的主要不良反应及防治策略

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英文篇名：Main Adverse Reactions and Prevention and Treatment Strategies of Statins in Clinical Application 作者：黄骞 英文作者：HUANG Qian;Department of Pharmacy,Deyang City People's Hospital; 关键词：他汀类药物 ; 不良反应 ; 防治策略 英文关键词：Statins;;Adverse reactions;;Prevention and treatment strategies 中文刊名：ZHJK 英文刊名：Smart Healthcare 机构：德阳市人民医院药剂科; 出版日期：2019-04-25 出版单位：智慧健康 年：2019 期：v.5 语种：中文; 页：ZHJK201912040 页数：2 CN：12 ISSN：10-1365/TN 分类号：84-85

摘要

目的探讨他汀类药物在临床应用中的主要不良反应及防治策略。方法将我院2018年1月至2018年12月收治的112例使用他汀类药物的患者为例,将其平均分为两组,其中按照常规方法使用他汀类药物的56例患者命名为对照组,针对不良反应采取防治策略使用他汀类药物的56例患者命名为观察组。结果观察组患者治疗总有效率为96.43%,优于对照组;观察组患者的不良反应率为7.14%,低于对照组的23.21%,且观察组没有患者发生肌肉不良反应。结论临床上针对他汀类药物在使用过程中的主要不良反应采取防治策略,可有效降低不良反应发生率,能够在保证患者治疗效果的同时,改善患者生活质量,值得临床上推广应用。
        Objective To investigate main adverse reactions and prevention and treatment strategies of statins in clinical application. Methods Treat 112 patients with statins in our hospital from January 2018 to December 2018 as examples, divide them into two groups in average. 56 cases with statins according to routine method were included in control group, and 56 cases with statins according to prevention and treatment strategy against adverse reactions as observation group. Results Total effective rate of observation group was 96.43%, higher than control group. Adverse reaction rate of observation group was 7.14%, lower than 23.21% of control group, and there was no muscle adverse reactions in observation group. Conclusion Prevention and treatment strategy against main adverse reactions of statins can reduce adverse reactions incidence effectively, ensure treatment effect of patients, and improve their life quality,which is worthy of clinical promotion and application.

引文

[1]袁成莹,侯原平,常晶,等.他汀类药物在临床应用中的主要不良反应及防治策略[J].中华老年多器官疾病杂志,2018,17(12):949-951.
    [2]谭国平.以他汀类为基础的降脂药物联合应用发生不良反应的相关危险因素分析[J].中国当代医药,2019,26(01):184-186.