昆山地区人群骨量减低患病率调查

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英文篇名：Investigation of osteopenia prevalence in populations of Kunshan area 作者：郝彦明 ; 王洪震 ; 雷小宝 ; 张盼盼 ; 陆荣柱 ; 方玲娜 ; 徐又佳 ; 李翀 英文作者：HAO Yan-ming;WANG Hong-zhen;LEI Xiao-bao;ZHANG Pan-pan;LU Rong-zhu;FANG Ling-na;XU You-jia;LI Chong;Orthopaedics Department,Kunshan First People's Hospital;Orthopaedics Department,Second Affiliated Hospital of Soochow University; 关键词：骨密度 ; 骨量减低 ; 骨质疏松 英文关键词：bone mineral density;;osteopenia;;osteoporosis 中文刊名：GUSS 英文刊名：Chinese Journal of Osteoporosis and Bone Mineral Research 机构：昆山市第一人民医院骨科;苏州大学附属第二医院骨科; 出版日期：2019-03-10 出版单位：中华骨质疏松和骨矿盐疾病杂志 年：2019 期：v.12 基金：昆山市社会发展科技专项(ks1531) 语种：中文; 页：GUSS201902006 页数：4 CN：02 ISSN：11-5685/R 分类号：33-36

摘要

目的调查江苏昆山地区骨量减低的患病率及发病趋势,提高骨量减低认知度,为预防骨质疏松提供依据。方法随机抽取2015年1月至2016年12月来昆山市第一人民医院检测骨密度(bone mineral density,BMD)的1 551例20～80岁人员,采用双能X线吸收测量仪(DEXA)测量腰椎及左侧股骨BMD,并记录检测人员的体质量指数(body mass index,BMI)。结果 1 551例受检人群中,男性924例,女性627例。男性人群中,股骨颈BMD随着年龄递增呈现下降趋势(P<0. 05);女性腰椎和股骨颈BMD在50岁之后均急剧下降,51～70岁组下降趋势最为明显(P <0. 05)。受检人员中腰椎骨量减低165例,患病率为10. 64%;骨质疏松23例,患病率为1. 48%;股骨颈骨量减低患病率为14. 44%,骨质疏松患病率为0. 39%。进一步分析显示,和≤50岁人群相比,女性51～70岁和≥71岁年龄段骨量减低和骨质疏松患病率增加极为显著(P<0. 001)。结论昆山地区中老年患者存在较高骨量减低患病率,需进一步分析并预防治疗。
        Objective To investigate the prevalence of osteopenia in Kunshan area,and to improve the awareness of low bone mass,so as to provide evidence for the prevention of osteoporosis. Methods Totally 1 551 individuals aged from 20 to 80 years old who came to Kunshan First People's Hospital from Jan. 2015 to Dec. 2016 to detect bone mineral density( BMD) were randomly selected. BMD at the lumbar spine and the left femur were measured by dual energy X-ray absorptiometry( DEXA),and the body mass index( BMI) was recorded. Results There were 924 men and 627 women in the examined population. In men,BMD at femoral neck decreased slowly( P < 0. 05) with increasing age. In women,both lumbar spine and femoral neck BMDs decreased sharply after the age of 50,especially between the ages of50-70( P < 0. 05). In lumbar spine,there were 165 cases of osteopenia,the prevalence was 10. 64%; there were 23 cases of osteoporosis,the prevalence was 1. 48%. In femoral neck,the prevalence of osteopenia higher( 14. 44%) and the prevalence of osteoporosis was relatively small( 0. 39%). Further analysis showed that the prevalences of osteopenia and osteoporosis in women aged 51-70 and ≥71 years were significantly higher than those in the population under 50 years of age( P<0. 001). Conclusion There is higher prevalence of osteopenia in middle-aged patients in Kunshan,further analysis and prevention should be done.

引文

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