禽流感病毒的传播及流行进化特点
详细信息 查看官网全文
- 英文论文题名：Progress In Molecular Biological Studies On The Transmission And Epidemic Of Avian Influenza Virus
- 论文作者：孙佳楠 ; 王楠楠 ; 周铁忠 ; 徐鹏
- 英文论文作者：SUN Jia-nan ; WANG Nan-nan ; XU Peng ; ZHOU Tiezhong ; College of Animal Husbandry and Veterinary ; Jinzhou Medical University
- 年：2016
- 作者机构：锦州医科大学畜牧兽医学院;
- 论文关键词：禽流感病毒 ; 传播 ; 流行 ; 分子生物学 ; 研究进展
- 英文论文关键词：avian influenza virus ; transmission ; epidemic ; molecular biology ; research progress
- 会议召开时间：2016-07-20
- 会议录名称：中国畜牧兽医学会兽医公共卫生学分会第五次学术研讨会论文集
- 语种：中文
- 分类号：S852.65
- 学会代码：SYGW
- 会议名称：中国畜牧兽医学会兽医公共卫生学分会第五次学术研讨会
- 会议地点：中国内蒙古通辽
- 主办单位：中国畜牧兽医学会兽医公共卫生学分会
- 学会名称：中国畜牧兽医学会兽医公共卫生学分会
- 页数：5
- 文件大小：506k
- 原文格式：D
- 会议级别：全国
摘要
禽流感病毒(AIV),尤其是高致病性禽流感病毒是一种可以引起人兽共患病的病原,由其引发的禽流感疫情不仅给养禽业带来了严重打击,而且也对人类健康和生命安全带来了严重威胁。尽管目前还未发生人际传播,但该病毒一旦与人流感病毒重组,将会转变为可人间传播的高致死性流感病毒,从而导致新的流感大流行。文章述了近些年来禽流感病毒的传播机制,血凝素和聚合酶与禽流感病毒跨宿主传播的关系,禽流感病毒的流行与进化特点等国内外研究成果,为禽流感的科学防控提供技术依据。
Avian influenza virus(AIV),especially the highly pathogenic avian influenza virus,is a causative agent of a zoonotic disease.The outbreaks of AIV have devastated the poultry industry worldwide and also brought a serious threat to public health.Although the virus shows little ability of transmission between humans,a process of genetic reassortment could occur in a human co-infected with avian influenza A virus and a human strain of influenza A virus.In this paper,the domestic and foreign research results on the transmission mechanism of avian influenza virus,the relationship between avian influenza virus hemagglutinin and polymerase and inter host transmission,prevalence and evolution characteristics of avian influenza virus,the technical basis for scientific prevention and control of avian influenza was provided.
Avian influenza virus(AIV),especially the highly pathogenic avian influenza virus,is a causative agent of a zoonotic disease.The outbreaks of AIV have devastated the poultry industry worldwide and also brought a serious threat to public health.Although the virus shows little ability of transmission between humans,a process of genetic reassortment could occur in a human co-infected with avian influenza A virus and a human strain of influenza A virus.In this paper,the domestic and foreign research results on the transmission mechanism of avian influenza virus,the relationship between avian influenza virus hemagglutinin and polymerase and inter host transmission,prevalence and evolution characteristics of avian influenza virus,the technical basis for scientific prevention and control of avian influenza was provided.
引文
[1]Perdue M,Suarze D.Structural features of the avian influenza virus heamagglutinin that Influence virulence[J].Vet Micro,2000,74:77-86.
[2]张增峰,樊晓晖,陈晓燕,等.禽流感病毒H9N2在人肺组织的复制[J].病毒学报,2013,29(2),206-210.
[3]Tumpey T,Maines T,Van H,et al.A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission[J].Science,2007,315(5812):655-659.
[4]Matrosovich M,Gambaryan A,Teneberg S,et al.Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site[J].Virology,1997,233(1):224-234.
[5]Gao Y,Zhang Y,Shinya K,et al.Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host[J].PLo S Pathog,2009,5(12):e1000709.
[6]Qi W,Tian J,Su S,et al.Identification of potential virulence determinants associated H9N2 avian influenza virus PB2 E627K mutation by comparative proteomics[J].Proteomics,2015,15(9):1512-1524.
[7]Bussey K,Bousse T,Desmet E,et al.PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells[J].J Virol,2010,84(9):4395-406.
[8]Mehle A,Doudna J.An inhibitory activity in human cells restricts the function of an avian-like influenza viruspolymerase[J].Cell Host Microbe,2008,4(2):111-122.
[9]Yamada S,Hatta M,Staker B.L,et al.Biological and structural characterization of a host-adapting amino acid in influenza virus[J].PLo S Pathog,2010,6(8):e1001034.
[10]Fauci A S.Emerging and re-emerging infectious diseases:influenza as a prototype of the host-pathogen balancing act[J].Cell,2006,124(4):665-670.
[11]Desselberger U,Nakajima K,Alfino P,et al.Biochemical evidence that new influenza virus strains in nature may arise by recombination(reassortment)[J].Proc Natl Acad Sci,1978,75(7):3341-3345.
[12]Olsen B,Munster V J,Wallensten A,et al.Global patterns of influenza A virus in wild birds[J].Science,2006,312(5772):384-388.
[13]Capua I,Alexander D J.Avian influenza infections in birds a moving target[J].Influenza Other Respi Viruses,2007,1(1):11-18.
[14]Galloway S E,Reed M L,Russell C J,et al.Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and p H of fusion:implications for host range and adaptation[J].PLo S Pathog,2013,9(2):e1003151.
[15]Stieneke,Vey M,Angliker H.Influenza virus hemagglutinin with multibasic cleavage site is activated by furin,a subtilisinlike endoprotease[J].EMBO J,1992,11(7):2407-2414.
[2]张增峰,樊晓晖,陈晓燕,等.禽流感病毒H9N2在人肺组织的复制[J].病毒学报,2013,29(2),206-210.
[3]Tumpey T,Maines T,Van H,et al.A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission[J].Science,2007,315(5812):655-659.
[4]Matrosovich M,Gambaryan A,Teneberg S,et al.Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site[J].Virology,1997,233(1):224-234.
[5]Gao Y,Zhang Y,Shinya K,et al.Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host[J].PLo S Pathog,2009,5(12):e1000709.
[6]Qi W,Tian J,Su S,et al.Identification of potential virulence determinants associated H9N2 avian influenza virus PB2 E627K mutation by comparative proteomics[J].Proteomics,2015,15(9):1512-1524.
[7]Bussey K,Bousse T,Desmet E,et al.PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells[J].J Virol,2010,84(9):4395-406.
[8]Mehle A,Doudna J.An inhibitory activity in human cells restricts the function of an avian-like influenza viruspolymerase[J].Cell Host Microbe,2008,4(2):111-122.
[9]Yamada S,Hatta M,Staker B.L,et al.Biological and structural characterization of a host-adapting amino acid in influenza virus[J].PLo S Pathog,2010,6(8):e1001034.
[10]Fauci A S.Emerging and re-emerging infectious diseases:influenza as a prototype of the host-pathogen balancing act[J].Cell,2006,124(4):665-670.
[11]Desselberger U,Nakajima K,Alfino P,et al.Biochemical evidence that new influenza virus strains in nature may arise by recombination(reassortment)[J].Proc Natl Acad Sci,1978,75(7):3341-3345.
[12]Olsen B,Munster V J,Wallensten A,et al.Global patterns of influenza A virus in wild birds[J].Science,2006,312(5772):384-388.
[13]Capua I,Alexander D J.Avian influenza infections in birds a moving target[J].Influenza Other Respi Viruses,2007,1(1):11-18.
[14]Galloway S E,Reed M L,Russell C J,et al.Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and p H of fusion:implications for host range and adaptation[J].PLo S Pathog,2013,9(2):e1003151.
[15]Stieneke,Vey M,Angliker H.Influenza virus hemagglutinin with multibasic cleavage site is activated by furin,a subtilisinlike endoprotease[J].EMBO J,1992,11(7):2407-2414.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |