小儿手足口病的临床表现与治疗研究

详细信息    查看官网全文

• 英文论文题名：Study the clinical manifestation and treatment of Hand foot and mouth disease of Children
• 论文作者：周燕辉
• 英文论文作者：Zhou Yanhui ; Sichuan Meishan District Maternal and child health care and family planning service center
• 年：2017
• 作者机构：四川眉山彭山区妇幼保健计划生育服务中心;
• 论文关键词：小儿手足口病 ; 常规治疗 ; 康复新液
• 英文论文关键词：pediatric HFMD ; routine treatment ; Kangfuxin Liquid
• 会议召开时间：2017-05-26
• 会议录名称：2017年《中国组织化学与细胞化学杂志》临床研讨会论文集
• 语种：中文
• 分类号：R725.1
• 学会代码：ZHXB
• 会议名称：2017年《中国组织化学与细胞化学杂志》临床研讨会
• 会议地点：中国湖北武汉
• 主办单位：《中国组织化学与细胞化学杂志》社有限公司
• 学会名称：《中国组织化学与细胞化学杂志》社有限公司
• 页数：2
• 文件大小：252k
• 原文格式：O
• 会议级别：全国

摘要

目的:观察分析小儿手足口病的临床症状特征,并通过常规治疗与康复新液联合常规治疗的疗效对比探究治疗方法。方法:选取2013年7月-2015年7月期间于我院儿科进行诊断与治疗的110名小儿手足口病患儿作为研究对象,随机均分为两组,将采取常规治疗的55名患儿设为对照组,对康复新液联合常规治疗的55名患儿设为观察组。分别比较治疗后两组患儿临床症状改善情况、治疗前后各免疫球蛋白水平比较以及乳酸与C反应蛋白(CRP)的改善情况。结果:110名患儿经过退热、抗病毒治疗等对症治疗均康复出院。两组患儿住院天数、退烧时间、精神恢复时间、肢体抖动消退时间差异不明显,P值均大于0.05,无统计学意义。观察组患儿乳酸与C反应蛋白(CRP)改善情况、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)改善情况均优于对照组,P值小于0.05,统计学意义存在。免疫球蛋白M(IgM)无明显差异,P值均大于0.05,无统计学意义。结论:通过退热、抗病毒治疗等对症治疗与康复新液联合常规治疗均能有效改善患儿手足口病临床症状,但康复新液对免疫蛋白以及乳酸与C反应蛋白(CRP)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)水平的改善幅度更大,对患儿免疫力的恢复有促进作用。
Objective:To observe and analysis the clinical symptoms of Hand foot and mouth disease,and compared the curative effect and research treatments between conventional treatment and conventional treatment combined with rehabilitation of Kang Fu Xin liquid.Methods:Selected 110 cases of children with Hand foot and mouth disease who were diagnosed and treated in the department of pediatric in our hospital from July 2013 to July 2015 as the research objects.And randomly divided them into two groups.Selected 55 cases of children who were treated with conventional treatment as the control group,55 cases of children who were treated with the rehabilitation of Kang Fu Xin liquid combined with conventional treatment as the observation group.Compared the improvement of clinical symptoms,the levels of immunoglobulins before and after treatment,and the improvement of lactic acid and C-reactive protein(CRP) between the two groups.Results:110 cases of children recovered and discharged after antipyretic,antiviral treatment and other symptomatic treatments.There was no significant difference in hospitalization days,antipyretic time,mental recovery time,limb shaking subsided time between the two groups,P >0.05.The improvement of lactic acid and C-reactive protein(CRP),immunoglobulin A(IgA) and immunoglobulin G(IgG) of the observation group were better than those of the control group,P <0.05,the difference was significant.There was no significant difference in the two groups of immunog lobulin M(IgM)(P > 0.05).Conclusion:The antipyretic,antiviral therapy and symptomatic treatment and Kangfuxin Liquid Combined with conventional treatment can both effectively improve the clinical symptoms of HFMD,But the Kangfuxin Liquid improved the level of C reactive protein(CRP),immunoglobulin A(IgA),immunoglobulin G(IgG) more significantly,and can promote the recovery of childrens immunity.

引文

[1]石佑根.小儿手足口病119例临床分析[J].蚌埠医学院学报,2013,38(2):184-186.
    [2]任彦,李颖,刘亚敏,等.330例小儿手足口病的病例分析[J].中华实验和临床感染病杂志电子版,2012,06(5):13-16.
    [3]林海波,刘晓娟,钟文明.小儿重症手足口病临床特征及危险因素分析[J].职业与健康,2013,29(16):2056-2058.
    [4]李雪红,樊云秀,叶伟杰.小儿手足口病122例实验室检测结果与治疗[J].中国临床研究,2015,28(6):785-787.
    [5]易冬玲,李继科.312例小儿重型手足口病临床治疗及分析[J].重庆医学,2012,41(22):2268-2269.
    [6]谢扬学,何淑君.康复新液治疗小儿手足口病疗效分析[J].现代预防医学,2012,39(1):4039-4039.
    [7]张古英,李三妮,齐林.小儿手足口病药物治疗调查分析[J].河北医药,2013,35(16):2517-2519.
    [8]刘跃,吴智娟.小儿手足口病172例临床分析[J].检验医学与临床,2007,4(2):127-128.
    [9]白秀堂.小儿手足口病200例临床分析[J].山西医药杂志,2016,45(14):1686-1688.
    [10]刘文琴.小儿手足口病43例临床观察与护理[J].基层医学论坛,2016,20(24):3433-3434.
    [11]张玉琨,杨巧芝,刘钢,等.清热解毒合剂治疗小儿重症手足口病临床观察[J].中国中医急症,2015,24(8):1483-1484.
    [12]王勇,方红星,刘艳,等.康复新液治疗小儿手足口病的临床观察[J].中国药房,2016(20):2846-2848.