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子宫内膜异位症辨证用药方略的文献研究
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摘要
目的通过研究近20年来关于子宫内膜异位症中药内服及外用灌肠文献,探索现代中医对于子宫内膜异位症的辨证用药规律,并对其中医治疗机理及现代药理进行分析,冀望更好的指导临床。
     方法筛选1989年1月至2008年12月生物医学期刊发表的有关现代中医子宫内膜异位症辨证方药的资料。对符合标准的文献进行中医辨证治法、遣方用药归纳,并用EXCEL软件进行数据统计分析。归纳总结出子宫内膜异位症的辨证用药规律。
     结果
     1.内服方内异症的治疗以活血化瘀为主要治法,占56.74%,其次是补肾化瘀法占23.4%,清热化瘀法占9.22%,化痰消癥法占9.22%,其他治法占1.42%。
     2.在252首内服方剂中,活血化瘀药出现频次最高,95.63%的方剂中出现活血化瘀药,其次是补虚药68.53%;在2474味中药中,活血化瘀药出现味数最高,达1051味,频次占42.48%,其次是补虚药518味,频次20.94%,两者共占63.42%。
     3.灌肠方32首方剂中,活血化瘀类药出现频次最高,96.88%的方剂中出现活血化瘀药,其次是清热药68.75%;270味中药中,活血化瘀药出现味数最高,达142味,频次占52.59%,其次是清热药,频次21.48%,两者共占74.07%。
     4.化痰消癥法占9.22%,化痰利湿药出现42.06%;而温通药在方中出现31.35%,但以寒凝血瘀为主要证型的治法却出现较少。
     5.莪术、三棱、桃仁、丹参、玄胡、川芎、五灵脂、蒲黄、红花、水蛭是内服方治疗子宫内膜异位症活血化瘀药的高频药物;当归、菟丝子、淫羊藿、白芍、黄芪、甘草、续断、熟地黄、巴戟天、党参是内服方治疗子宫内膜异位症补虚药的高频药物;莪术、赤芍、当归、三棱、桃仁、丹参、玄胡、香附、川芎、五灵脂是内服方治疗子宫内膜异位症的高频药物;莪术、三棱、赤芍、败酱草、丹参、乳香、没药、红藤是灌肠方治疗子宫内膜异位症的高频药物。
     6.内服方高频药物中活血化瘀药出现7味,占70%,清热凉血药、补虚药、理气药各出现1味,各占10%;灌肠方高频药物中活血化瘀药出现5味,占62.5%,清热药出现2味,占25%,清热凉血药出现1味,占12.5%。
     7.治疗子宫内膜异位症高频药物主要归肝经、脾经和心经。
     结论
     1.血瘀是内异症的根本病机,活血化瘀是内异症的主要治法。
     2.痰瘀互结是内异症病机的补充。
     3.内服方以活血化瘀药及补虚药为主要药物,灌肠方以活血化瘀药、清热药为主要药物。内服方体现整体观念,兼顾标本虚实,攻守相兼;而灌肠方局部治疗,用药偏攻,以治标为要。
     4.莪术、赤芍、当归、三棱、桃仁、丹参、玄胡、香附、川芎、五灵脂是内服方治疗子宫内膜异位症的高频药物;莪术、三棱、赤芍、败酱草、丹参、乳香、没药、红藤是灌肠方治疗子宫内膜异位症的高频药物。
Objective 1.Through investigating the literature research last twenlty years of endometriosis both internal and external(enema) use of Chinese medicine to explore the principle of syndrome differentiation and treatment of endometriosis as well as to analyze the mechanism of treatment in TCM and modern pharmacology in diagnosis and prescription.
     Method Screening medical information on endometriosis about diagnosis and prescription pubulish in Biomedical journals from Jan.1989 to Dec.2008.Using EXCEL statistical software to analyze the data induced by syndrome differentiation and medication among standards-compliant literature,then summarized the regularity.
     Result
     1.Activating blood and removing stasis is the main treatment of Chinese herbal medicine of endometriosis,accounting for 56.74%,followed by method of reinforcing kidney and removing stasis 23.4%,clearing away heat and resolving blood stasis 9.22%,blood rheology 9.22%,other treatment 1.42%.
     2.Activating microcirculation and removing stasis medicinal herbs has the highest frequency of 95.63%in the 252 prescriptions,followed by restore deficiency herbs 68.53%.Activating microcirculation and removing stasis medicinal herbs appears 1051,has the highest frequency of 42.48%in the 2474 Chinese medicine,followed by 518 restore deficiency herbs 20.94%,which together accounted for 63.42%.
     3.Activating microcirculation and removing stasis medicinal herbs has the highest frequency of 96.88%in the 32 enema prescription,followed by heat clearing herbs 68.75%.Activating microcirculation and removing stasis medicinal herbs appears 142,has the highest frequency of 52.59%in the 270 Chinese medicine,followed by heat clearing herbs 21.48%,which together accounts for 74.07%.
     4.Clearing away heat and resolving blood stasis accounts for 9.22%,and eliminat dampness resolv phlegm herbs accounts for 42.06%,while manganese accounts for 31.35%,but the treatment for cold coagulation and blood stasis type appears seldom.
     5.Rhizoma curcumae,Rhizoma sparganii,Semen persicae,Radix salviae miltiorrhizae,Rhizoma corydalis,Rhizoma chuanxiong,Faeces trogopterori, Pollen typhae,Flos carthami and Hirudo are microcirculation and removing stasis medicinal herbs with a higher frequency of Chinese herbal medicine in treating endometriosis.Radix angelicae sinensis,Semen cuscutae,Herba epimedii,Radix paeoniae alba,Radix astragali,Radix glycyrrhizae,Radix dipsaci,Radix rehmanniae preparata,Radix morindae officinalis and Radix codonopsis are restore deficiency drugs with a higher frequency of Chinese herbal medicine in treating endometriosis.Rhizoma curcumae,Radix paeoniae rubra,Radix angelicae sinensis,Rhizoma sparganii,Semen persicae,Radix salviae miltiorrhizae,Rhizoma corydalis,Rhizoma cyperi,Rhizoma chuanxiong and Faeces trogopterori are drugs with a higher frequency of Chinese herbal medicine,while Rhizoma curcumae,Rhizoma sparganii,Radix paeoniae rubra, Herba potriniae,Radix salviae miltiorrhizae,Olibanum,Myrrha and Caulis sargentodoxae are drugs with a higher frequency of enema prescription in treating endometriosis.
     6.There are 7 herbs of activating microcirculation and removing stasis medicine which accounts for 70%,while blood cooling herbs,restore deficiency herbs and Qi smoothing herbs appears only once respectively,agent each 10% at a higher frequency of Chinese herbal medicine.There are 5 herbs of activating microcirculation and removing stasis medicinal at 62.5%, while heat clearing herbs 2 at 25%and blood cooling herbs 1 at 12.5%at a higher frequency of enema prescription.
     7.Drugs with a higher frequency of endometriosis treatment are goes to Liver meridian,Spleen meridian and Heart meridian.
     Conclusion
     1.Blood stasis is the basic pathogenesis of endometriosis,while activating blood and removing stasis is the major therapy.
     2.Accumulation of phlegm-damp in collateral is a supplement pathogenesis of endometriosis.
     3.Internal Chinese herbal medicine is mainly made up of activating microcirculation and removing stasis medicinal herbs and restore deficiency herbs,while enema prescription is mainly made up of activating microcirculation and removing stasis medicinal herbs and heat clearing drug as the main drugs.Compared to enema prescription is as a local therapy with reducing herbs,internal Chinese herbal medicine incarnate the concept of wholism,which is simultaneous treatment of root and tip.
     4.Rhizoma curcumae,Radix paeoniae rubra,Radix angelicae sinensis, Rhizoma sparganii,Semen persicae,Radix salviae miltiorrhizae,Rhizoma corydalis,Rhizoma cyperi,Rhizoma chuanxiong and Faeces trogopterori are drugs with a higher frequency of Chinese herbal medicine,while Rhizoma curcumae,Rhizoma sparganii,Radix paeoniae rubra,Herba potriniae,Radix salviae miltiorrhizae,Olibanum,Myrrha and Caulis sargentodoxae are drugs with a higher frequency of enema prescription in treating endometriosis.
引文
[1]Giudice L,Kao L.Endometrlosis.Lancet,2004;364(9447):1789-1799.
    [2]郎景和.子宫内膜异位症研究进展.引进国外医药技术与设备,1999;5(8):16-19.
    [3]丰有吉,沈铿主编.妇产科学,北京:人民卫生出版社,2005,第1版:357-366.
    [4]郎景和主编.子宫内膜异位症的基础与临床研究,北京:中国协和医科大学出版社,2003,第1版:35-45.
    [5]郎景和.加强子宫内膜异位症基础与临床研究.中华妇产科杂志,2001;36(12):711-713.
    [6]郎景和主编.子宫内膜异位症的基础与临床研究,北京:中国协和医科大学出版社,2003,第1版:46-50.
    [7]Goldstein DP,DeCholnoky C,Emans SJ,et al.Laparoscopy in the diagnosis and management of pelvic pain in adolescents.J Reprod Med,1980;(24):251-256.
    [8]Cramer DW,Wilson E,Stillman RJ,et al.The ralationship of endometriosis to menstrual characterristics,smoking and exercise.JAMA,1986;255:l904-1908.
    [9]潘凌亚,韩美龄,吴葆桢.月经状况与子宫内膜异位症发病的关系.中华妇产科杂志,1993;(28):147-149.
    [10]Candiani GB,Danesino V,Gastaldi A,et al.Reproductive and menstrual factors and risk of pelvic and ovarian endometriosis.Fertil Steril,1991;56:230-234.
    [11]潘凌亚,宋鸿钊.生殖活动与子宫内膜异位症发病的关系.中华妇产科杂志,1994;29(3):150-153.
    [12]Vessey MP,Villard-Mackintosh L,Painter R.Epidemiologyof endometriosis in women attending family planning clinics.BMJ,1993;306:182-184.
    [13]周应芳.盆腔子宫内膜异位症发病因素的调查.中华妇产科杂志,1995;(30):356.
    [14]将因琪.人工流产与子宫内膜异位症.实用妇科与产科杂志,1987;(3):181.
    [15]孙咏梅,金海红,徐应军,等.盆腔子宫内膜异位症相关因素分析.中国综合临床,2007;23(11):1035-1037.
    [16]潘凌亚,宋鸿钊,吴葆桢.生殖活动与子宫内膜异位症发病的关系,中华妇产科杂志,1994;(29):150-153.
    [17]崔怀琳.子宫内膜异位症128例临床分析.武汉医学杂志,1992;(3):143-144.
    [18]单红英,李楠,赵霞.子宫内膜异位症发病机制的研究进展.中国误诊学杂志,2007:7(24):5721-5723.
    [19]郎景和主编.子宫内膜异位症的基础与临床研究,北京:中国协和医科大学出版社,2003,第1版:51-56.
    [20]李明清,李大金.子宫内膜异位症:一种自身免疫病.国外医学妇产科学分册,2007;34(5):348-351.
    [21]柳玲.二噁英与子宫内膜异位症发病关系的研究进展.实用医学杂志,2007;23(8):1269-1271.
    [22]Hirotaka M,Tetsuo M,Emi H,et al.Noninvasive and real-time assessment of reconstructed funetional human endometrium in NOD/SCID/γc~(null)immunodeficient mice.PNAS,2007;104:1925-1930.
    [23]Zheng W,Li N,Wang J,et al.Initial endometriosis showing direct morphologic evidence of metaplasia in the pathogenesis of Ovarian endometriosis.Int J Gynecol Pathol,2005;24(2):164-172.
    [24]王秀霞,张合龙.子宫内膜异位症的免疫学发病机制及防治.中国实用妇科与产科杂志,2007;(12):906-908.
    [25]顾彧,林金芳.单核细胞趋化蛋白1对子宫内膜间质细胞分泌血管内皮生长因子的影响.中华妇产科杂志,2004;39(3):187-189.
    [26]郎景和,冷金花,赵栋,钟森.第八届国际子宫内膜异位症学术会议纪要.中华妇产科杂志,2002;(10):638-640.
    [27]郎景和,冷金花,周应芳,等.子宫内膜异位症.现代妇产科学进展,2006;15(3):161-172.
    [28]卢翠云,齐荣义,卢翠敏.神经-内分泌-免疫网络在子宫内膜异位症发病机制中的作用.北京医学,2004;(2):137-138.
    [29]程明军,徐丛剑.子宫内膜异位症的发病机制理论及学说.中国实用妇科与产科杂志,2007:23(7):561-562.
    [30]OsugaY,KogaK,Tsutsumio,et la.Stemcellfactor(SCF) concentrations in peirtonela fluid of women with or without endometriosis.AmJ Reprod Immunol,2000;4(4):231-235.
    [31]GarryR,CreweJ.A new look at menstruation:the role of bone mallow derived stem cells in mensturla regeneration.Europ J Obstet Gynecol Reprod Biol,2005;123(1):4.
    [32]Starzinski-Powitz A,Zeitvogel A,Schreiner A,et al.Endometriosis-a stem cell disease?.Zentralblatt fur Gynakologie,2003;125(7-8):235-238.
    [33]司徒仪主编.子宫内膜异位症中西医结合治疗,北京:人民卫生出版社,2004,第1版:71.
    [34]Mathur SP.Autoimmunity in endometriosis:relevance to infertility.Am J Reprod,2000;44(2):89-95.
    [35]Inagaki J,Sugiura-Ogasawara M,Nomizu M,et al.An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients.Hum Reprod,2003;18(3):544-549.
    [36]Cunha Filho JS,Gross JL,Lemos NA,et al.Hyperprolaetinemia and luteal phase insufficiency in infertile patients with mild and minimal endometriosis.Horm Metab Res,2001;33(4):216-220.
    [37]Gottschalk C,Malberg K,Arndt M,et al.Matfix metalloproteinases and TACE play a role in the pathogenesis of endometriosis.Adv Med Biol,2000:(477):483-496.
    [38]王琳,史长旭.子宫内膜异位症痛经患者腹腔液前列腺素测定28例分析.中国实用妇科与产科杂志,1996;12(2):99-100.
    [39]徐丛剑,金志军主编.子宫内膜异位症,北京:人民卫生出版社,2002,第1版:173.
    [40]屈佳妮,付庆国,王正阳.卵巢子宫内膜异位囊肿超声分型及其临床价值.临床超声医学杂志,2007;9(2):91-93.
    [41]乐杰,林仲秋.妇产科常用诊断技术及特殊检查,北京:人民军医出版社,2006,第1版:219-240.
    [42]Harada T,Kubota T,Aso T.Usefulness of CA199 versus CA125 for the diagnosis of endometriosis.Fertility and Sterility,2002;78(4):733-739.
    [43]Gagne D,Rivard M,Page M,et al.Development of a nonsurgical diagnosis tool for endometriosis based on the detection of endometrial leukocyte subsets and serum CA125 levels.Fertility and Sterility,2003;80(4):876-885.
    [44]Bedaiwy M A,Falcone T.Laboratory testing for endometriosis.Clinica Chimica Acta,2004;340(1-2):41-56.
    [45]胡芬,张炜.子宫内膜异位症生化标记物的临床意义.中国妇幼健康研究,2006;17(4):327-329.
    [46]冷金花,郎景和,杨佳欣.子宫内膜异位症的诊治进展.中华妇产科杂志,2000;35(1):53-54.
    [47]郎景和.子宫内膜异位症的临床病理类型及其对治疗的意义.中华妇产科杂志,2001;36(11):699-702.
    [48]罗丽兰主编.不孕与不育,北京:人民卫生出版社,2005,第11版:308.
    [49]郎景和.进一步加强子宫内膜异位症的基础与临床研究.中华妇产科杂志,2001;(36):711-713.
    [50]周应芳,崔恒,乔杰,等.应重视子宫内膜异位症诊断与治疗的规范化.中国妇产科临床杂志,2001;(2):68-71.
    [51]郭红燕,韩劲松,马彩虹,等.腹腔镜下卵巢囊肿手术的卫生经济学分析.中国微创外科杂志,2002;(2):149-151.
    [52]Vercellini P,Vendola N,Bocciolone L,et al.Reliability of the visual diagnosis of ovarian endometriosis.Fertil Steril,1991;(56):1198-1200.
    [53]Beretta P,Franchi M,Ghezzi F,et al.Randomized clinical trial o two laparoscopic treatments of endometriomas:cystectomy versus drainage and coagulation.Fertil Steril,1998;(70):l176-1180.
    [54]周应芳.子宫内膜异位症的临床诊断和治疗.中华妇产科杂志,2005;1(40):67-70.
    [55]Maruyama M,Osuga Y,Momoeda M,et al.Pregnancy rates after laparoscopic treatment.Differences related to tubal status and presence of endometriosis.J Reprod Med,2000;(45):89-93.
    [56]Adamson GD,Pasta DJ.Surgical treatment of endometriosis-associated infertility:meta-analysis compared with survival analysis.Am J Obstet Gynecol,1994;(171):1488-1504.
    [57]Rickes D,Nickel I,Kropf S,et al.Increased pregnancy rates after ul tralong postoperative therapy with gonadotropin-releasing hormone analogs in patients with endometriosis.Fertil Steril,2002;(78):757-762.
    [58]Vercellini P,Frontino G,De Giorgi O,et al.Continuous use of an oral contraceptive for endometriosis-associated recurrent dysmenorrhea that does not respond to a cyclic pill regimen.Fertil Steril,2003;(80):560-563.
    [59]Surrey ES,Hornstein MD.Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis:long-term follow-up.Obstet Gynecol,2002;(99):709-719.
    [60]NAP A W,GRIFFIOEN A W,DUNSELMAN G A,et al.Antiangiogenesis therapy for endometriosis.J Clin Endocfinol Metab,2004;89(3):1089-1095.
    [61]谢洪哲,郭煦.子宫内膜异位症.新医学,2008;39(1):4-7.
    [62]COBELLIS L,RAZZI S,DE SIMONE S,et al.The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis.Eur J Obstet Gynecol Reprod Biol,2004;116(1):100-102.
    [63]Vercellini P,Frontino G,De Giorgi O,et al.Comparison of a levonorgestrel-releasing intrauterine device versus expectant management after conservative surgery for symptomatic endometriosis:a pilot study.Fertil Steril,2003;(80):305-309.
    [64]Kupker W,Felberbaum RE,Krapp M,et al.Use of GnRH antagonists in the treatment of endometriosis.Reprod Biomed Online,2002;(5):12-16.
    [65]陈金娇.周期疗法治疗子宫内膜异位不孕症.山东中医杂志,2002;(1):24-25.
    [66]黄素英,莫惠玉,王海丽.中国百年百名中医临床家丛书·蔡小荪,北京:中国中医药出版社,2002,第2版.
    [67]李秀英,刘爽.马中夫治疗子宫内膜异位症的三三理论.辽宁中医杂志,2003;30(2):105.
    [68]尤昭玲,王若光,付灵梅.气虚血瘀和益气化瘀法在妇科疾病治疗中的地位和意义.湖南中医药导报,2001;7(9):440-441.
    [69]罗颂平.罗元恺妇科经验集,上海:上海科学技术出版社,2005,第1版.
    [70]北京中医医院.刘奉五妇科经验,北京:人民卫生出版社,2006,第1版:244-245.
    [71]李祥云,刘健,胡晓梅,等.补肾祛瘀法治疗子宫内膜异位症的实验研究.中医杂志,1997;38(5):292-293.
    [72]唐荣.祛瘀散结补肾法治疗子宫内膜异位症.辽宁中医杂志,2002;29(3):145.
    [73]许丽芬,韩冰,李同玺.活血化瘀、软坚散结法(妇痛宁)对子宫内膜异位症神经内分泌影响的实验研究.天津中医,2002;19(1):61-62.
    [74]张志枫,俞超芹,王大增,等.化瘀通腑法对子宫内膜异位症痛经的治疗作用及机制探讨.中医杂志,1995;36(11):679-681.
    [75]李丽芸,王小云.中医妇科临证证治,广州:广东人民出版社,1999,第1版.
    [76]王祖倩,张志枫.化瘀通腑法治疗子宫内膜异位症的临床及实验研究-附95例病例分析.上海中医药杂志,1992;(9):8-11.
    [77]林英,苗玉平.宣郁通经汤治疗子宫内膜异位致不孕症51例疗效观察.中医药研究,2001;(4):23-24.
    [78]赵瑞华.许润三教授从肝肾论治不孕症之经验.中医函授通讯,1994;(2):20-21.
    [79]金季玲.活血补肾法治疗子宫内膜异位症不孕35例,陕西中医,1994;(12):532.
    [80]张丽君.补肾化瘀法治疗子宫内膜异位合并不孕症的实验和临床研究.上海中医药杂志,1996;(11):12-14.
    [81]张丽君,庄克利.子宫内膜异位症诊断与治法浅议.湖北中医,1999;(1):26.
    [82]姚石安,姚寓晨.治疗子宫内膜异位症的临床探讨.实用中西医杂志,1998;(4):299.
    [83]崔火仙.何嘉琳老中医治疗不孕症经验.新中医,2001;33(6):8.
    [84]许润三.不孕症辨治之我见.江苏中医药,2002;23(5):1-3.
    [85]张锡珍.李祥云教授治疗子宫内膜异位症的经验-附39例不孕验案分析.陕西中医,2000;21(9):410-411.
    [86]张静.江希萍治疗子宫内异症所致不孕的经验.江苏中医,1999;(20):6-7.
    [87]司徒仪主编.子宫内膜异位症中西医结合治疗,北京:人民卫生出版社,2004,第1版:231-233.
    [88]金季玲.加味桂枝茯苓丸治疗子宫内膜异位症95例.辽宁中医杂志,1994;21(6):39.
    [89]杨渐.中药灌肠治疗子宫内膜异位症50例.陕西中医,2005;26(10):1007.
    [90]北京中医医院.刘奉五妇科经验,北京:人民卫生出版社,2006,第1版:244-245.
    [91]瞿晓竹.蔡小荪治疗子宫内膜异位症的经验.中医杂志,1991;(11):15-16.
    [92]黄瑛,达美君.专科专病名医临证经验丛书·妇科病,北京:人民卫生出版社,2002,第1版.
    [93]陈爱兰,周玉峰,张少霞.异位康治疗子宫内膜异位症的实验研究.河北中医,1999;21(6):385-387.
    [94]杨洪艳,欧阳惠卿.达那唑、罗氏内异方对实验性子宫内膜异位症大鼠血液流变性影响.安徽中医学院学报,2001;20(2):45.
    [95]司徒仪,樊阴萍,潘华新.莪棱胶囊对大鼠实验性子宫内膜异位症作用机理探讨.中医杂志,2002;41(4):237.
    [96]梁雪芳.司徒仪主任诊治子宫内膜异位症经验.天津中医,2002;19(3):71.
    [97]夏桂成.辨治子宫内膜异位证的体会.天津中医学院学报,1995;(4):1-2.
    [98]邢翠玲,康幼雯.辨证治疗子宫内膜异位症120例.中医研究,2000;13(4):54.
    [99]毕蓉蓉.中医治疗子宫内膜异位症探讨.中国血液流变学杂志,2001;11(1):69.
    [100]李祥云.子宫内膜异位症的诊治与体会.辽宁中医杂志,2004;31(10):804.
    [101]张旭宾.子官内膜异位症的中医病因病机及证治特色探析.新中医,2003;35(8):5-6.
    [102]顺惠芳.化瘀消痰法治疗子官内膜异位症痛经70例疗效观察.新中医,2003;35(10):17.
    [103]杨峰.中医药治疗子宫内膜异位症的研究进展.甘肃中医,2007:20(9):35-37.
    [104]陈怡,徐晓玉,叶兰,等.三棱丸抑制大鼠子宫内膜异位症血管生成及VEGF,TNF-α表达的研究.中国中药杂志,2008;33(3):303-307.
    [105]吴凡,陈峰,康玉平.异位散对子宫内膜异位症家兔血液流变性及血管活性物质的影响.中国微循环,2003;7(6):355.
    [106]吴新华,鞠红梅,庞爱梅,等.康正消异颗粒对120例子宫内膜异位症患者免疫调节功能的影响.中医杂志,2003;44(9):680.
    [107]洪敏,华永庆,余黎,等.化瘀补肾方提取物干预大鼠子宫内膜异位症.中国中药杂志,2003;28(1):69.
    [108]杨洪艳,欧阳惠卿,罗颂平,等.中药对实验性子官内膜异位症血清内分泌激素及激素受体的影响.新中医,2001,33(6):75.
    [109]魏绍斌,曹亚芳,王毅郭,等.内异康复栓对子宫内膜异位症大鼠异位和在位内膜细胞色素C和生存素表达的影响.中国中西医结合杂志,2008;28(2):139-141.
    [110]余跃飞,肖纯,黄桂林,等.复宫宁诱导异位子宫内膜细胞凋亡的超微病理学研究.河北中医,2001;23(12):951.
    [111]杨桂云,刘红林.补肾活血方对子宫内膜异位症不孕腹腔液微环境改善作用的实验研究.中医药学刊,2003;21(1):57.
    [112]付金荣,李祥云,董肇杨.血管加压素与子宫内膜异位症疼痛的关系及中药对其的影响.上海中医药杂志,2000;(10):10-11.
    [113]宋知理,陈秀英.曹玲仙治疗子宫内膜异位症经验.中医杂志,2008;49(1):19-20.
    [114]张晓甦.子宫内膜异位症的辨治初探.陕西中医,2006;27(6):693-695.
    [115]汤月萍.中医辨治子宫内膜异位症的临床体会.辽宁中医杂志,2005;32(12):1275.
    [116]石显方,傅文录.石景亮治疗子宫内膜异位症经验举隅.上海中医药杂志,2005;39(7):29-30.
    [117]南振军.桂莲内异汤治疗子宫内膜异位42例.陕西中医,2007;28(11):1481-1482.
    [118]徐燕.散结镇痛胶囊治疗子宫内膜异位症76例.陕西中医,2008;29(3):330.
    [119]王燕,陈双厚,刘瑞华.桂附胶囊治疗子宫内膜异位症实验研究.中华中医药杂志,2007;22(11):801-804.
    [120]黄洁明,欧阳惠卿,许丽绵,等.子宫内膜异位症血瘀证本质探讨及罗氏内异方对其血管内环境的影响.河南中医,2006;26(10):23-25.
    [121]张磊,祝佩芹.清异汤保留灌肠治疗直肠子宫内膜异位症疗效观察.四川中医,2007;25(1):265-266.
    [122]孔桂茹.中药直肠滴注治疗子宫内膜异位症.青海医药杂志,2006;36(7):74.
    [123]许佳年.子宫内膜异位症辨治探析.陕西中医,2007;28(11):1556.
    [124]阮继源,汪慧敏.隔药饼灸配合穴位注射治疗子宫内膜异位症46例.实用中医 药杂志,2001;17(3):19.
    [125]Chang NL.用针灸和草药治疗子宫内膜异位症.国外医学中医中药分册,2001;23(1):58.
    [126]熊运碧,祝育德.低频治疗仪治疗子宫内膜异位症所致痛经的疗效观察.北京中医药大学学报,2006;13(3):23-24.
    [127]陈光盛,汪慧敏.治疗子宫内膜异位症经验.中医杂志,2006;47(5):342-343.
    [128]丁哲,丁岩.耳穴贴压治疗痛经68例.中国民间疗法,2004;12(11):18-19.
    [129]卢晓男,徐向荣,林丽君.抗异种玉汤联合GnRH-a治疗重度子宫内膜异位症不孕患者疗效观察.中国中西医结合杂志,2007;27(11):980-982.
    [130]薛秀花,康晓露.中西医结合治疗子宫内膜异位症41例.陕西中医,2007;28(9):1194-1195.
    [131]马宝璋主编.中医妇科学,北京:中国中医药出版社,2004,第1版.
    [132]张承烈,王金生.从瘀痰论治子宫内膜异位症探讨.浙江中西医结合杂志,2003;13(7):428-429.
    [133]苏庆民.活血化瘀研究的创新与发展.医学与哲学,1996;17(11):570-573.
    [134]郑有顺主编.中医血药药理与应用,北京:军事医学科学出版社,1999,第1版:63-64.
    [135]高月平.温肾疏肝、祛痰化瘀法治疗盆腔子宫内膜异位症37例.南京中医药大学学报,1996;12(5):55.
    [136]韩冰.妇痛宁治疗子宫内膜异位症临床和实验研究.中医杂志,1997;38(8):488-490.
    [137]周元荣,孙方亮,刘爱梅.痰瘀分消法治疗子宫内膜异位症60例临床观察.新中医,1999;31(1):19-20.
    [138]周军.中药补益药的研究概况.新疆中医药,2003;21(1):51-52.
    [139]黄兆胜主编.中药学,北京:人民卫生出版社,2002,第1版.
    [140]杨卫平,王贵英主编.中药学,北京:中国古籍出版社,2002,第1版.
    [141]汪德清,沈文梅,田亚平,等.黄芪活性提取成份对膜脂质过氧化损伤的保护作用.中国中药杂志,1996;21(12):746-748.
    [142]宋德明,苏海,吴美华,等.川芎嗪、丹参对成纤维细胞胶原台成和细胞增殖的影响.中国中西医结合杂志,1998;18(7):423.
    [143]李仪奎主编.中药药理学,北京:中国中医药出版杜,1992,第1版:184-187.

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