人类免疫缺陷病毒母婴阻断新生儿喂养不耐受的临床特点分析
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摘要
目的探讨人类免疫缺陷病毒(HIV)母婴阻断新生儿喂养不耐受的临床特点。方法对广州市第八人民医院2012年6月至2016年6月收治的208例HIV母婴阻断新生儿喂养不耐受情况进行回顾性分析。结果 HIV母婴阻断新生儿喂养不耐受的发生率为36.1%,其中足月儿为30.5%,早产儿为67.7%,早产儿喂养不耐受发生率高于足月儿(P<0.05)。喂养不耐受发生时间多为生后4 d内,其症状表现以呕吐、腹胀、胃潴留及血便为多见。早产儿腹胀及胃潴留发生率高于足月儿(P<0.05);足月儿呕吐及血便发生率高于早产儿(P<0.05)。结论 HIV母婴阻断新生儿喂养不耐受发生时间多在生后4 d内,在此期间应严密监测,对相关临床表现早期识别及早期干预。
Objective To investigate the clinical features of feeding intolerance in infants who were implemented prevention of mother-to-child transmission of HIV.Methods The data of 208 cases of prevention of mother-to-child transmission of HIV in infants who were hospitalized in the Guangzhou Eighth people′s Hospital from June 2012 to June 2016 were summarized,and their clinical features were analyzed retrospectively.Results The incidence of feeding intolerance in infants who were implemented prevention of mother-to-child transmission of HIV was 36.1%.The incidence was 30.5% in term infants and was 67.7% in premature infants.Feeding intolerance often occured within 4 days after birth.The common clinical manifestations usually were abdominal distension,vomiting,gastric retention and bloody stool.The most common presenting symptoms in premature infants were abdominal distension and gastric retention,and in term infants were vomiting and bloody stool.Conclusion Feeding intolerance in infants who were implemented prevention of mother-to-child transmission of HIV often occured within 4 days after birth,during this period should be closely monitored for early identification and treatment of feeding intolerance.
Objective To investigate the clinical features of feeding intolerance in infants who were implemented prevention of mother-to-child transmission of HIV.Methods The data of 208 cases of prevention of mother-to-child transmission of HIV in infants who were hospitalized in the Guangzhou Eighth people′s Hospital from June 2012 to June 2016 were summarized,and their clinical features were analyzed retrospectively.Results The incidence of feeding intolerance in infants who were implemented prevention of mother-to-child transmission of HIV was 36.1%.The incidence was 30.5% in term infants and was 67.7% in premature infants.Feeding intolerance often occured within 4 days after birth.The common clinical manifestations usually were abdominal distension,vomiting,gastric retention and bloody stool.The most common presenting symptoms in premature infants were abdominal distension and gastric retention,and in term infants were vomiting and bloody stool.Conclusion Feeding intolerance in infants who were implemented prevention of mother-to-child transmission of HIV often occured within 4 days after birth,during this period should be closely monitored for early identification and treatment of feeding intolerance.
引文
[1] 徐洁,刘艳.社区人类免疫缺陷病毒母婴健康教育对预防孕妇艾滋病感染的预警效果分析[J].广东医学,2014,35(9):1408-1410.
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[7] 陆薇,张红波,黄娟,等.喂养方式对剖宫产婴儿大便性状及肠道菌群的影响[J].临床儿科杂志,2011,29(5):450-453.
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[9] 张良娟,虎崇康,林燕,等.早产儿喂养不耐受肠道菌群多样性研究[J].中国妇幼健康研究,2015,26(2):171-174.
[10] 国家免费艾滋病抗病毒治疗手册编写组.国家免费艾滋病抗病毒药物治疗手册[M].3版.北京:人民卫生出版社,2012:12-26.
[11] 预防艾滋病、梅毒和乙肝母婴传播工作实施方案.http://www.gov.cn/ zwgk/2011_02 /24/content_1809_480.htm.
[12] 邵肖梅.早产儿消化系统的特点及喂养[J].中国实用儿科杂志,2000,15(12):716-718.
[13] 封志纯,钟梅.实用早产儿与早产儿学[M].北京:军事医学科学出版社,2010:256-258.
[14] 王雪松,潘家华.深度水解蛋白配方奶在早期早产儿喂养中的疗效观察[J].安徽医药,2015,19(7):1379-1382.
[2] KUZMA-O′REILLY B,DUENAS ML,GREECHER C,et al.Evaluation,development,and im- plementation of potentially better practices in neonatal intensive care nutr- ition [J],Pediatrics,2003,111(4 pt 2):461-470.
[3] KLEINMAN R E,BERSETH C,CASTILLO DURAN C,etal.perinatal nutrition and gastr- ointestinaldisorders:working group report of the second world congress of pediatric gastroenterology,hepatology and nutrition[J].J PediatrGastroen- terol Nutr,2004,39(6):S703-S710.
[4] 裴怀腾,霍晓慧,赵宏.新生儿喂养不耐受的临床特征及高危因素分析[J].中国基层医药,2007,14(8):1285-1287.
[5] 陈琼彭,文涛,方进博.基于反应范围模型的早产儿喂养不耐受风险因素分析[J].中国实用护理杂志,2016,32(23):1798-1802.
[6] 朱绪亮,杨嘉琛,张俊,等.早产喂养不耐受的发病率和临床特征分析[J].延安大学学报(医学科学版),2013,11(1):36- 37.
[7] 陆薇,张红波,黄娟,等.喂养方式对剖宫产婴儿大便性状及肠道菌群的影响[J].临床儿科杂志,2011,29(5):450-453.
[8] 王同友,王红兵.小剂量红霉素联合微生态制剂治疗早产儿喂养不耐受疗效观察[J].山东医药,2012,52(33):64-65.
[9] 张良娟,虎崇康,林燕,等.早产儿喂养不耐受肠道菌群多样性研究[J].中国妇幼健康研究,2015,26(2):171-174.
[10] 国家免费艾滋病抗病毒治疗手册编写组.国家免费艾滋病抗病毒药物治疗手册[M].3版.北京:人民卫生出版社,2012:12-26.
[11] 预防艾滋病、梅毒和乙肝母婴传播工作实施方案.http://www.gov.cn/ zwgk/2011_02 /24/content_1809_480.htm.
[12] 邵肖梅.早产儿消化系统的特点及喂养[J].中国实用儿科杂志,2000,15(12):716-718.
[13] 封志纯,钟梅.实用早产儿与早产儿学[M].北京:军事医学科学出版社,2010:256-258.
[14] 王雪松,潘家华.深度水解蛋白配方奶在早期早产儿喂养中的疗效观察[J].安徽医药,2015,19(7):1379-1382.
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