乳酸杆菌联合保妇康凝胶治疗非特异性阴道炎的临床观察
摘要
目的探讨乳酸杆菌联合保妇康凝胶治疗非特异性阴道炎的临床疗效。方法将120例非特异性阴道炎分为两组,保妇康凝胶组60例给予保妇康凝胶治疗,联合组60例予乳酸杆菌联合保妇康凝胶治疗。对比两组临床疗效及复发率。结果联合组治疗总有效率(96.67%)明显高于保妇康凝胶组(71.67%),差异具有统计学意义(P<0.05);联合组治疗后的阴道清洁度Ⅰ-Ⅱ度比例96.67%及阴道分泌物pH<4.5比例95.00%明显优于保妇康凝胶组73.33%、75.00%(P<0.05)。联合组复发率(1.67%)明显低于保妇康凝胶组(16.67%),差异具有统计学意义(P<0.05)。结论采用乳酸杆菌联合保妇康凝胶治疗非特异性阴道炎效果较明显,能明显减轻患者的临床症状,改善阴道清洁度及阴道分泌物pH值,并且复发率低。
引文
[1]赵品红,徐琳,李楠,等.保妇康凝胶与乳酸杆菌治疗非特异性阴道炎的疗效观察.中国妇幼保健,2015,30(12):1949
[2]Walker PP,Reynolds MT,Ashbee HR,et al.Vaginal yeasts in the era of over the counter antifungals.Sex Transm Infect,2011,76(6):437
[3]陈万瑛,于爱萍,阿丽玛·阿西木,等.不同疗程乳酸杆菌制剂诊治妊娠期细菌性阴道炎的进展.检验医学与临床,2013,10(3):305
[4]乐杰.妇产科学.6版.北京:人民卫生出版社,2005:261
[5]Al-Mayahie SM.Phenotypic and genotypic comparison of ESBL production by Vaginal Escherichia coli isolates from pregnant and non-pregnant women.Annals of Clinical Microbiology&Antimicrobials,2013,12(1):7
[6]黄新颜,陈敏枝,蒋敏,等.产后6周妇女阴道菌群分布及应用阴道乳杆菌胶囊的效果.中国妇幼保健,2012,27(17):2588
[7]叶宇齐.双唑泰泡腾片与乳酸杆菌活菌胶囊联合治疗细菌性阴道病的临床疗效分析.微生物与感染,2011,6(2):97
[8]Lamont RF,Sobel JD,Akins RA,et al.The vaginal microbiome:new information about genital tract flora using molecular based techniques.BJOG,2011,118(5):533
[9]姚莉,李琦伟.乳酸杆菌活菌制剂治疗阴道炎41例的临床及细菌学疗效.中国药业,2013,22(11):12
[10]Larsson PG,Brandsborg E,Forsum U,et al.Extended antimicrobial treatment of bacterial vaginosis combined with human lactobacilli to find the best treatment and minimize the risk of relapses.BMC Infect Dis,2011,11(6):223
[11]廖育新,刘静,黄瑞莲,等.乳酸杆菌活菌剂治疗老年性阴道炎临床疗效观察.海南医学,2015,26(1):131
[12]管庆红,陈迪文,吴美芬,等.不同给药方案对阴道炎患者阴道乳酸菌恢复及复发率的影响.中国性科学,2014,23(8):18
[13]Sobel JD,Subramanian C,Foxman B,et al.Mixed vaginitis more than coinfection and with therapeutic implications.Curr Infect Dis Rep,2013,15(2):104
[14]雷英,岳莹利,范爱萍,等.阴道炎功能学检测的临床应用价值评估.山东医药,2014,54(41):70
[15]何文静.定君生在预防阴道炎复发中的临床效果.中国微生态学杂志,2012,24(3):281
[16]Marrazzo JM.Interpreting the epidemiology and natural history of bacterial vaginosis:are we still confused.Anaembe,201l,17(4):186
[17]韩鲜梅.阴道炎患者不同给药方案对阴道乳酸菌恢复及复发率的影响.现代中西医结合杂志,2015,24(14):1559
[18]Hui CK.Recurrent extended-spectrum beta-lactamase-producing Escherichia coli urinary tract infection due to an infected intrauterine device.Singapore Med J,2013,55(2):e28
[19]黄新颜,罗伟东,洪展彤,等.阴道乳杆菌胶囊对产后6周妇女非特异性阴道炎防治作用的临床探讨.中国妇幼保健,2015,30(2):259
[2]Walker PP,Reynolds MT,Ashbee HR,et al.Vaginal yeasts in the era of over the counter antifungals.Sex Transm Infect,2011,76(6):437
[3]陈万瑛,于爱萍,阿丽玛·阿西木,等.不同疗程乳酸杆菌制剂诊治妊娠期细菌性阴道炎的进展.检验医学与临床,2013,10(3):305
[4]乐杰.妇产科学.6版.北京:人民卫生出版社,2005:261
[5]Al-Mayahie SM.Phenotypic and genotypic comparison of ESBL production by Vaginal Escherichia coli isolates from pregnant and non-pregnant women.Annals of Clinical Microbiology&Antimicrobials,2013,12(1):7
[6]黄新颜,陈敏枝,蒋敏,等.产后6周妇女阴道菌群分布及应用阴道乳杆菌胶囊的效果.中国妇幼保健,2012,27(17):2588
[7]叶宇齐.双唑泰泡腾片与乳酸杆菌活菌胶囊联合治疗细菌性阴道病的临床疗效分析.微生物与感染,2011,6(2):97
[8]Lamont RF,Sobel JD,Akins RA,et al.The vaginal microbiome:new information about genital tract flora using molecular based techniques.BJOG,2011,118(5):533
[9]姚莉,李琦伟.乳酸杆菌活菌制剂治疗阴道炎41例的临床及细菌学疗效.中国药业,2013,22(11):12
[10]Larsson PG,Brandsborg E,Forsum U,et al.Extended antimicrobial treatment of bacterial vaginosis combined with human lactobacilli to find the best treatment and minimize the risk of relapses.BMC Infect Dis,2011,11(6):223
[11]廖育新,刘静,黄瑞莲,等.乳酸杆菌活菌剂治疗老年性阴道炎临床疗效观察.海南医学,2015,26(1):131
[12]管庆红,陈迪文,吴美芬,等.不同给药方案对阴道炎患者阴道乳酸菌恢复及复发率的影响.中国性科学,2014,23(8):18
[13]Sobel JD,Subramanian C,Foxman B,et al.Mixed vaginitis more than coinfection and with therapeutic implications.Curr Infect Dis Rep,2013,15(2):104
[14]雷英,岳莹利,范爱萍,等.阴道炎功能学检测的临床应用价值评估.山东医药,2014,54(41):70
[15]何文静.定君生在预防阴道炎复发中的临床效果.中国微生态学杂志,2012,24(3):281
[16]Marrazzo JM.Interpreting the epidemiology and natural history of bacterial vaginosis:are we still confused.Anaembe,201l,17(4):186
[17]韩鲜梅.阴道炎患者不同给药方案对阴道乳酸菌恢复及复发率的影响.现代中西医结合杂志,2015,24(14):1559
[18]Hui CK.Recurrent extended-spectrum beta-lactamase-producing Escherichia coli urinary tract infection due to an infected intrauterine device.Singapore Med J,2013,55(2):e28
[19]黄新颜,罗伟东,洪展彤,等.阴道乳杆菌胶囊对产后6周妇女非特异性阴道炎防治作用的临床探讨.中国妇幼保健,2015,30(2):259
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