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在“Elsevier”中，命中：1,171条，耗时：0.0849619 秒

1.Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells

作者：Haitao Wangp>ap>p> ; p>p>1p> ; Qishan Zhangp>ap>p> ; p>p>1p> ; Lang Zhangp>ap> ; Peter J. Littlep>bp> ; Xiaochun Xiep>ap> ; Qian Mengp>ap> ; Yannan Renp>ap> ; Lihua Zhoup>dp> ; Guoquan Gaop>dp> ; Remi Quirionp>cp> ; Wenhua Zhengp>ap>p> ; p>p>whzheng123@gmail.comp>

关键词：IGF-1 ; PRAS40 ; PI3K/Akt ; MAPK ; Neuronal cells survival

刊名：Neuroscience Letters

出版年：2012

2.IL-7 splicing variant IL-7未5 induces human breast cancer cell proliferation via activation of PI3K/Akt pathway

作者：Deshun Panp>ap>p> ; p>p>bp>p> ; p>p>1p> ; Bing Liup>bp>p> ; p>p>1p> ; Xiaobao Jinp>ap>p> ; p>p>1p> ; Jiayong Zhup>ap>p> ; p>p>zhujiayong888@163.comp>

关键词：IL-7 variant ; IL-7未5 ; Human breast cancer ; Proliferation ; Cell cycle ; Cyclin D1 ; p27kip1 ; PI3K/Akt

刊名：Biochemical and Biophysical Research Communications

出版年：2012

3.Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells

作者：Kathy W.K. Tsep>ap>p> ; p>p>1p>p> ; p>p>kathytse.wk@gmail.comp> ; Kevin B.L. Linp>ap>p> ; p>p>2p>p> ; p>p>kelin@bccrc.cap> ; May Dang-Lawsonp>ap>p> ; p>p>mpdang@interchange.ubc.cap> ; Angel Guzman-Perezp>bp>p> ; p>p>angel.guzman-perez@pfizer.comp> ; Gary E. Aspnesp>bp>p> ; p>p>gary.aspnes@pfizer.comp> ; Leonard Buckbinderp>bp>p> ; p>p>leonard.buckbinder@pfizer.comp> ; Michael R. Goldp>ap>p> ; p>p>mgold@mail.ubc.cap>

关键词：APC ; antigen presenting cell ; BCR ; B cell receptor ; FAK ; focal adhesion kinase ; ICAM-1 ; intercellular adhesion molecule-1 ; LFA-1 ; lymphocyte function-associated antigen-1 (伪L尾2 integrin) ; MZ ; marginal zone ; PI3K ; phosphoinositide 3-kinase ; P-Akt ; phosph

刊名：Cellular Immunology

出版年：2012

4.BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin

作者：Pei-Pei Lip>1p> ; Dan-Dan Liup>1p> ; Yun-Jie Liu ; Shan-Shan Song ; Qing-Tong Wang ; Yan Chang ; Yu-Jing Wu ; Jing-Yu Chen ; Wen-Di Zhao ; Ling-Ling Zhangp> ; p>p>llzhang@ahmu.edu.cnp> ; Wei Weip> ; p>p>wwei@ahmu.edu.cnp>

关键词：PI3K/Akt/mTOR ; Signaling ; BAFF/BAFF-R ; Collagen induced arthritis ; Paeoniflorin

刊名：Journal of Ethnopharmacology

出版年：2012

5.Pyrazolopyrimidines as dual Akt/p70S6K inhibitors

作者：Kenneth D. Rice ; Moon H. Kimp> ; p>p>&dagger ; p>p> ; p>p>mkim58@ncc.re.krp> ; Joerg Busseniusp> ; p>p>jbusseni@exelixis.comp> ; Neel K. Anand ; Charles M. Blazey ; Owen J. Bowles ; Lynne Canne-Bannen ; Diva S.-M. Chan ; Baili Chen ; Erick W. Co ; Simona Costanzo ; Steven C. DeFina ; Larisa Dubenko ; Stefan Engst ; Maurizio Franzini ; Ping Huang ; Vasu Jammalamadaka ; Richard G. Khoury ; Rhett R. Klein ; A.Douglas Laird ; Donna T. Le ; Morrison B. Mac ; David J. Matthews ; David Markby ; Nicole Miller ; John M. Nuss ; Jason J. Parks ; Tsze H. Tsang ; Amy L. Tsuhako ; Yong Wang ; Wei Xu

关键词：p70S6K inhibitor ; Akt inhibitor ; Pyrazolopyrimidine ; PI3K pathway ; Cancer

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

6.High-mobility group box-1 protein induces mucin 8 expression through the activation of the JNK and PI3K/Akt signal pathways in human airway epithelial cells

作者：Dong Eun Kimp>ap>p> ; p>p>1p> ; Kyoung-jin Minp>bp>p> ; p>p>1p> ; Jung Soo Kimp>cp> ; Taeg Kyu Kwonp>bp>p> ; p>p>kwontk@dsmc.or.krp>

关键词：HMGB1 ; Mucin 8 ; ROS ; JNK ; PI3K/Akt

刊名：Biochemical and Biophysical Research Communications

出版年：2012

7.Phenylbutyric acid induces the cellular senescence through an Akt/p21p>WAF1p> signaling pathway

作者：Hag Dong Kimp>ap>p> ; p>p>1p> ; Chang-Young Jangp>bp>p> ; p>p>1p> ; Jeong Min Choep>ap>p> ; p>p>cp>p> ; p>p>dp> ; Jeongwon Sohnp>cp>p> ; p>p>dp>p> ; p>p>biojs@korea.ac.krp> ; Joon Kimp>ap>p> ; p>p>joonkim@korea.ac.krp>

关键词：Cellular senescence ; ER stress ; PBA ; Akt ; PERK

刊名：Biochemical and Biophysical Research Communications

出版年：2012

8.Sevoflurane postconditioning involves an up-regulation of HIF-1伪 and HO-1 expression via PI3K/Akt pathway in a rat model of focal cerebral ischemia

作者：Zhi Ye ; Qulian Guop> ; p>p>guoqulian7411@live.cnp> ; Pingping Xia ; Na Wang ; E. Wang ; Yajing Yuan

关键词：Sevoflurane postconditioning ; Cerebral ischemia&ndash ; reperfusion injury ; Neuroprotection ; Hypoxia inducible factor-1伪 (HIF-1伪) ; Heme oxygenase-1 (HO-1) ; Phosphatidylinositol-3-kinase (PI3K)/Akt

刊名：Brain Research

出版年：2012

9.CIP2A-mediated Akt activation plays a role in bortezomib-induced apoptosis in head and neck squamous cell carcinoma cells

作者：Yu-Chin Linp>ap>p> ; p>p>ep>p> ; p>p>fp> ; Kuei-Chiu Chenp>cp> ; Ching-Chow Chenp>ep> ; Ann-Lii Chengp>ap>p> ; p>p>bp>p> ; p>p>cp> ; Kuen-Feng Chenp>cp>p> ; p>p>dp>p> ; p>p>kfchen1970@ntu.edu.twp>

关键词：HNSCC ; head and neck squamous cell carcinoma ; HCC ; hepatocellular carcinoma ; CIP2A ; cancerous inhibitor of PP2A ; PP2A ; protein phosphatase 2A ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; PARP ; poly (ADP-ribose) polymeras

刊名：Oral Oncology

出版年：2012

10.Sp1 is involved in regulation of cystathionine 纬-lyase gene expression and biological function by PI3K/Akt pathway in human hepatocellular carcinoma cell lines

作者：Peng Yinp>ap> ; Chao Zhaop>ap> ; Zengxia Lip>ap>p> ; p>p>bp>p> ; p>p>cp> ; Chuanzhong Meip>ap> ; Wantong Yaop>ap> ; Yonglei Liup>ap> ; Na Lip>ap> ; Jingjing Qip>ap> ; Liying Wangp>ap>p> ; p>p>bp>p> ; p>p>cp> ; Yinghong Ship>dp> ; Shuangjian Qiup>dp> ; Jia Fanp>dp> ; Xiliang Zhap>ap>p> ; p>p>bp>p> ; p>p>cp>p> ; p>p>xlzha@shmu.edu.cnp>

关键词：CSE ; cystathionine 纬-lyase ; PLP ; pyridoxal-5&prime ; -phosphate ; PI3K ; phosphoinositide 3-kinase ; Myr-Akt2 ; myristylated variants of Akt2 ; IGF-1 ; insulin-like growth factor-1 ; PTEN ; phosphatase and tensing homolog ; CHX ; cycloheximide ; MEF ; mouse embryonic

刊名：Cellular Signalling

出版年：2012

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