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在“Elsevier”中，命中：273条，耗时：0.0979512 秒

1.S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition

作者：Weihua Liu^a ; ^b ; ¹ ; Tian Lan^c ; ¹ ; Xi Xie^a ; Kaipeng Huang^a ; Jing Peng^a ; Juan Huang^a ; Xiaoyan Shen^a ; Peiqing Liu^a ; Heqing Huang^a ; ^{huangheq@mail.sysu.edu.cn}

关键词：Diabetic nephropathy ; Sphingosine-1-phosphate ; Sphingosine-1-phosphate receptors ; Fibronectin ; Mitogen-activated protein kinase signaling pathway

刊名：Experimental Cell Research

出版年：2012

2.Knockdown of the sphingosine-1-phosphate receptor S1PR1reduces pain behaviors induced by local inflammation of the rat sensory ganglion

作者：Wenrui Xie^a ; ^{Xiewe@ucmail.uc.edu} ; Judith A. Strong^a ; ^{judith.strong@uc.edu} ; Joanne Kays^b ; ^{kaysj@iupui.edu} ; Grant D. Nicol^b ; ^{gnicol@iupui.edu} ; Jun-Ming Zhang^a ; ^{Jun-Ming.Zhang@uc.edu}

关键词：Sphingosine 1-phosphate ; S1PR1 ; Inflammation ; Dorsal root ganglion

刊名：Neuroscience Letters

出版年：2012

3.Indole-propionic acid derivatives as potent, S1P₃-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P₁) receptor agonists

作者：Qinghua Meng ; Baowei Zhao ; Qiongfeng Xu ; Xuesong Xu ; Guanghui Deng ; Chengyong Li ; Linbo Luan ; Feng Ren ; Hailong Wang ; Heng Xu ; Yan Xu ; Haibo Zhang ; Jia-Ning Xiang ; John D. Elliott ; Taylor B. Guo ; Yonggang Zhao ; Wei Zhang ; Hongtao Lu ; Xichen Lin ; ^{Xichen.2.Lin@gsk.com}

关键词：Sphingosine-1-phosphate ; Agonist ; Lymphopenia ; Experimental autoimmune encephalomyelitis (EAE) ; SAR

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

4.Sphingosine 1-phosphate (S1P)/S1P receptor 1 signaling regulates receptor activator of NF-魏B ligand (RANKL) expression in rheumatoid arthritis

作者：Harunori Takeshita^a ; Masayasu Kitano^a ; ^{mkitano6@hyo-med.ac.jp} ; Tsuyoshi Iwasaki^b ; Sachie Kitano^a ; Sachi Tsunemi^a ; Chieri Sato^a ; Masahiro Sekiguchi^a ; Naoto Azuma^a ; Keiji Miyazawa^c ; Timothy Hla^d ; Hajime Sano^a

关键词：Sphingosine 1-phosphate ; RANKL ; Rheumatoid arthritis

刊名：Biochemical and Biophysical Research Communications

出版年：2012

5.Sphingosine 1-phosphate antagonizes the effect of all-trans retinoic acid (ATRA) in a human colon cancer cell line by modulation of RAR尾 expression

作者：De-Fu Sun^a ; ^b ; ¹ ; Zu-Hua Gao^c ; ¹ ; Hui-Ping Liu^a ; Yi Yuan^a ; Xian-Jun Qu^a ; ^{qxj@sdu.edu.cn}

关键词：Sphingosine 1-phosphate (S1P) ; Retinoids ; All-trans retinoic acid (ATRA) ; HT-29 cells ; Retinoid acid receptor 尾 (RAR尾) ; SphK2

刊名：Cancer Letters

出版年：2012

6.A polysaccharides MDG-1 augments survival in the ischemic heart by inducing S1P release and S1P₁ expression

作者：Shuo Wang^a ; Xiao Lin^a ; Ling-Yi Wang^a ; Ke-Feng Ruan^a ; Yi Feng^a ; ^{fyi@vip.sina.com} ; Xiao-Yan Li^b ; ^{lixiaoyan@hdbio.sciences.com}

关键词：HMEC-1 ; human microvascular endothelial cells-1 ; OGD ; oxygen glucose deprivation ; S1P ; sphingosine 1-phosphate ; SPHK ; sphingosine kinase ; S1P1 ; sphingosine 1-phosphate receptor 1 ; ERK ; extracellular signal regulated kinase ; SH ; sham operation ; AMI ; acute

刊名：International Journal of Biological Macromolecules

出版年：2012

7.Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R^{鈭?鈭?/sup>) mice}

作者：Francesco Poti^a ; Sara Costa^a ; Valeria Bergonzini^a ; Margherita Galletti^a ; Elisa Pignatti^a ; Christian Weber^b ; Manuela Simoni^a ; ¹ ; Jerzy-Roch Nofer^a ; ^c ; ¹ ; ^{nofer@uni-muenster.de}

关键词：ConA ; concanavalin A ; DMEM ; Dulbecco-modified Eagle's medium ; FCS ; fetal calf serum ; HDL ; high density lipoproteins ; LDL-R ; low density lipoprotein receptor ; LPS ; lipopolysaccharide ; S1P ; sphingosine 1-phosphate ; PBS ; phosphate-buffered saline ; S1PR1 ; S1P

刊名：Vascular Pharmacology

出版年：2012

8.Re-circulation of lymphocytes mediated by sphingosine-1-phosphate receptor-1 contributes to resistance against experimental infection with the protozoan parasite Trypanosoma cruzi

作者：Mariana R. Dominguez^a ; ^b ; Jonatan Ersching^a ; ^b ; Ramon Lemos^a ; ^b ; Alexandre V. Machado^c ; Oscar Bruna-Romero^d ; Mauricio M. Rodrigues^a ; ^b ; ^{mrodrigues@unifesp.br} ; José ; Ronnie C. de Vasconcelos^a ; ^b ; ^{jrcvasconcelos@gmail.com}

关键词：CD8 ; Protozoan ; FTY720 ; Gene-based vaccines

刊名：Vaccine

出版年：2012

9.Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death

作者：Min-Jung Kim ; Moon-Taek Park ; Chang-Hwan Yoon ; Joo-Yun Byun ; Su-Jae Lee

关键词：Sphingolipid metabolites ; Sphingosine-induced mitochondrial cell death ; Bak-dependent cell death by sphingosine ; Lck-mediated conformational activation of Bak

刊名：Biochemical and Biophysical Research Communications

出版年：2008

10.Lymphopenia induced by a novel selective S1P₁ antagonist structurally unrelated to S1P

作者：Yasuyuki Fujii^a ; ^{y.fujii@po.rd.taisho.co.jp} ; Hidenori Ohtake^a ; Naoya Ono^a ; Toshifumi Hara^a ; Takanobu Sakurai^a ; Syuya Takahashi^a ; Tetsuo Takayama^a ; Yoshiki Fukasawa^a ; Fumiyasu Shiozawa^a ; Narutoshi Tsukahara^c ; Takehiro Hirayama^c ; Yasuyuki Igarashi^b ; Ryo Goitsuka^c

关键词：S1P ; sphingosine 1-phosphate ; S1P1 ; type 1 sphingosine 1-phosphate receptor ; CHS ; contact hypersensitivity response ; HEK293 ; human embryonic kidney cell line ; CHO-K1 ; Chinese hamster ovary cell line ; HTS ; high-throughput screening ; GTP ; guanosine-5&prime

刊名：Biochimica et Biophysica Acta (BBA)/Molecular and Cell Biology of Lipids

出版年：2012

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