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在“Elsevier”中，命中：1,557条，耗时：0.0919594 秒

1.Acquired resistance to drugs targeting receptor tyrosine kinases

作者：Steven A. Rosenzweig ; ^{rosenzsa@musc.edu}

关键词：Akt ; Ak (mouse strain) &ndash ; thymoma ; Axl ; a receptor tyrosine kinase ; Bcr-Abl ; breakpoint cluster-Abelson tyrosine kinase ; CML ; chronic myelogenous Leukemia ; CrkL ; v-crk sarcoma virus CT10 oncogene homolog (avian)-like ; DACH1 ; Dachshund homolog 1 (Dros

刊名：Biochemical Pharmacology

出版年：2012

2.N⁴-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: Design, synthesis, and in vivo evaluation

作者：Aleem Gangjee^a ; ^{gangjee@duq.edu} ; Nilesh Zaware^a ; Sudhir Raghavan^a ; Jie Yang^a ; Jessica E. Thorpe^b ; Michael A. Ihnat^b

关键词：ATP ; adenosine 5&prime ; triphosphate ; VEGF ; vascular endothelial growth factor ; EGF ; epidermal growth factor ; PDGF ; platelet derived growth factor ; RTK ; receptor tyrosine kinase ; KDR ; kinase insert domain receptor ; VEGFR-2 ; vascular endothelial growth fact

刊名：Bioorganic and Medicinal Chemistry

出版年：2012

3.G protein coupled receptor transactivation: Extending the paradigm to include serine/threonine kinase receptors

作者：Micah L. Burch^a ; ^b ; Narin Osman^b ; ^c ; Robel Getachew^c ; Sefaa Al-aryahi^c ; Philip Poronnik^c ; Wenhua Zheng^d ; Michael A. Hill^c ; ^e ; Peter J. Little^a ; ^b ; ^c ; ^{peter.little@rmit.edu.au}

关键词：G protein coupled receptor ; Serine/threonine protein kinase receptor ; Transactivation ; Vascular smooth muscle ; Proteoglycan

刊名：The International Journal of Biochemistry and Cell Biology

出版年：2012

4.Thermostable direct hemolysin diminishes tyrosine phosphorylation of epidermal growth factor receptor through protein kinase C dependent mechanism

作者：Poulomee Karmakar ; Manoj K. Chakrabarti ; ^{mkc_niced@yahoo.co.in}

关键词：TDH ; thermostable direct hemolysin ; PKC ; protein kinase C ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-related kinase ; MEK ; mitogen activated protein kinase kinase/ERK kinase

刊名：Biochimica et Biophysica Acta (BBA)/General Subjects

出版年：2012

5.Evaluation of subchronic toxicity of SIM010603, a potent inhibitor of receptor tyrosine kinase, after 28-day repeated oral administration in SD rats and beagle dogs

作者：Yu Mao^a ; ¹ ; Zhenna Xia^a ; ¹ ; Xiaofang Zhang^a ; Ying Zong^a ; Lin Zhu^b ; Bojun Yuan^a ; ; Guocai Lu^a ; ^{luguo2007@yahoo.com.cn}

关键词：SIM010603 ; Receptor tyrosine kinase (RTK) inhibitor ; Subchronic toxicity ; Sunitinib

刊名：Food and Chemical Toxicology

出版年：2012

6.The formation of complex acetylcholine receptor clusters requires MuSK kinase activity and structural information from the MuSK extracellular domain

作者：Sania Mazhar ; Ruth Herbst ; ^{ruth.herbst@meduniwien.ac.at}

关键词：AChR ; acetylcholine receptor ; BGT ; bungarotoxin ; MuSK ; muscle-specific kinase ; NMJ ; neuromuscular junction ; PF ; post fusion ; RTK ; receptor tyrosine kinase

刊名：Molecular and Cellular Neuroscience

出版年：2012

7.Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation

作者：Shigeru Iwata ; MD ; PhD^a ; Kunihiro Yamaoka ; MD ; PhD^a ; Hiroaki Niiro ; MD ; PhD^b ; Kazuhisa Nakano ; MD ; PhD^a ; Sheau-Pey Wang ; MS^a ; Koichi Akashi ; MD ; PhD^b ; Yoshiya Tanaka ; MD ; PhD^a ; ^{tanaka@med.uoeh-u.ac.jp}

关键词：Syk ; Toll-like receptor 9 ; TNF receptor&ndash ; associated factor 6 ; B cells

刊名：Journal of Allergy and Clinical Immunology

出版年：2012

8.Ectodomain structures of Eph receptors

作者：Juha P. Himanen ; ^{himanenj@mskcc.org}

关键词：Eph receptors ; Ephrins ; Receptor tyrosine kinase ; Signaling ; Subclass specificity

刊名：Seminars in Cell and Developmental Biology

出版年：2012

9.Dynamics of receptor trafficking in tumorigenicity

作者：Christine A. Parachoniak¹ ; ² ; Morag Park¹ ; ² ; ³ ; ⁴ ; ^{morag.park@mcgill.ca}

关键词：endocytosis ; receptors ; cancer ; recycling ; integrin ; receptor tyrosine kinase

刊名：Trends in Cell Biology

出版年：2012

10.Overcoming Molecular Mechanisms of Resistance to First-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

作者：Jair Bar¹ ; ^{bar.jair@gmail.com} ; Amir Onn²

关键词：EGFR ; Irreversible tyrosine kinase inhibitors ; NSCLC ; Resistance ; Reversible tyrosine kinase inhibitors

刊名：Clinical Lung Cancer

出版年：2012

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