The geological storage of CO2 is widely accepted as an effective method to reduce the release of greenhouse gases to the atmosphere. In this study, an experimental method applied to a rock sample taken from Ordovician reef limestone of Tarim Basin was used to measure the residual gas saturation. Through simulating water flooding supercritical CO2 saturated core under 40 ℃ strata temperature, 8 MPa strata pressure, the pressure and flux change with time were observed during the course, and residual gas saturation was measured as 0.368.