An experiment on mixed mineral grains of quarts, plagioclase and calcite dissolved in several aqueous organic acid solutions was carried out. The purpose of the paper was to compare the dissolving rate of the minerals in formation water containing abundant low-molecular organic acids under reservoir condition and to probe the microcosmic mechanism of corrosion. The results indicated that all mineral grains were eroded more or less after the experiment, it exhibited that the weight of grain decreased, whereas the concentration of SiO2 and several metallic cations and pH in aqueous solution increased.