In past 30 years, the development of amplitude versus offset (AVO) research went up and down. In recent years, the AVO application has been extensively accepted and used rapidly. In the exploration of the heterogeneous reservoir, the AVO is an irreplaceable method, in comparison with others. In this paper, the authors discuss the influence of lateral small-scale size and velocity variation on the reflectivity coefficient by means of transverse small-scale design, forward simulation calculation, and comparison of theoretical values of Zoeppritz equation. The reflectivity variation depends on the lateral scale size and velocity. The authors find a rule of reflectivity coefficient with offset distance in the lateral velocity.