Qaizhong fault zone located in the central Qaidam Basin trends EW. The Indian plate underthrust Eurasian plate intensively in multi-stages during Himalayan period and Qaidam Basin remained in regional compression background. Based on analysis of palaeogeographic changes, basin superposition and isotopic age information for the Arkin, Qilian and Kunlun Mountains around the basin Qaizhong fault zone may be generated contemporanously with the break up of Proterozoic Rodinia ancient continent. They all belong to the huge EW-trending Dabie Mountains-Qinling-Kunlun orogenic belt. Qaidam Basin was exposed to Jinning, Caledonian, Hercynian and Yanshan movement, especially the Himalayan orogeny and the early structures are obscured by the later ones in this area.