The Pre-Mesozoic in China is dominated by marine deposits with multiple-layer series and multiple-type source rocks. The differential control of tectonic setting and sedimentary background results in significant differences in the quality and distribution of source rocks. During Sinian-Early Paleozoic (Z-O2), the main plates in China were in a tectonic-sedimentary period with ocean basin extending and landmass dispersing. Source rocks of passive continental margin slope facies were developed in the peripheries of main landmasses such as Huabei, Yangtze and Tarim. In the late of Early Paleozoic (O3-S), ocean basins subducted and ChinaAncientLand converged and took shape. Under the constraint of uplifts on plate margin, source rocks were mainly developed in intra-platform sags. Source rocks were deposited in the interior of deep faulted depression.