Located in the middle of NW Guizhou Pb-Zn metallogenetic province, Shaojiwan Pb-Zn deposit is a typical representative Pb-Zn deposits in the region, whose metal resources (Pb+Zn) are more than 0.2 Mt. In this study, the dispersed elements contents in different types of ore sulfides (pyrite, sphalerite, and galena) were analyzed by using the methods of Inductively Coupled Plasma Mass Spectrum (ICP-MS).The results show that content of Cd is higher than those of Ga, In, Se, Tl and Re, and they have different concentration characteristics in sulfides. The contents of Ga, Cd and In and the ratios of Ga/In and Zn/Cd in the sphalerite indicate that Shaojiwan Pb-Zn deposits formed under middle-high temperature conditions, and the metallogenetic deposit might be diplogenetic-regenerated.