This article studied and analyzed S isotopic and C, O isotopic of carbonate cements in ores of the Jinding lead-zinc polymetallic deposit. The results show that the CO₂ in ore-forming fluid was related to sedimentary organic matters and marine carbonates, it derived from thermal decomposition of marine carbonates and oxidation and decarbonxylation of sedimentary organic matters; the ore mineral composition of deposit reflects its metallogenic environment to be hyperoxia fugacity environment. The study of S isotopic characteristics show that S of gypsum ore body in deposit may come from Triassic ancient oceanic sulfate minerals, and S in metallic sulfide minerals is multi-sourced.