On June 28, 2010, a large-scale landslide occurred in the county of Guanling, Guizhou Province. On June 30, China Aero Geophysical Survey & Remote Sensing Center for Land and Resources (AGRS) carried out the urgent remote sensing flight disposed by China Geological Survey Administration, and high-resolution aerial image data of three days after landslide was captured. Then, ortho-rectification was completed for disaster interpretation and analysis. QuickBird data, aerial photo, 1∶50 000 digital topographic data and DEM were taken as pre-and post-6.28 landslide remote sensing data and geographical control data respectively. Based on the analysis of formation factors of 6.28 landslide and hidden geo-hazard interpretation, suggestions are proposed for disaster prevention and mitigation.