The Devonian-Permian organic reefs in the south of Guizhou Province are distributed widely.They can be divided into two types of platform margin reef and intra platform reef according to their ancient geographical positions of development.The types of reef limestone have four types of framestone,bafflestone-framestone,framestone-bafflestone and bondstone.Recent researches indicate that the organic reef of Devonian-Permian in the depression in the south of Guizhou Province has preferable petroliferous property and presents the process of oil-gas migration and accumulation, having a favorable oil-gas exploration perspective.The study area is one of the key areas for seeking oil-gas reservoirs of organic reefs.