Baishiquan, Tianyu, and Tianxiang Cu-Ni-sulfide deposits are found recently in Xinjiang Hami. These deposits are located in Northern margin of the Central Tianshan Block, and south of Shaquanzi deep fracture. In this area, the quantity and scale of these Cu-Ni-sulfide deposits are small. Because of the advantageous minerogenetic conditions, there is great potential in search of new and large deposits. In this paper, based on searching metallogenic background and geological features of the three deposits, established the tentative metallogenic and exploration model, and pointed out the ore search direction.