Mongolia-Hinggan Orogen is an important metallogenic belt of China; many Mo-deposits were discovered in this belt recently owing to the great deal of input by government and companies. Based on the study of igneous rocks, the regional geological maps and Mo-deposits, this paper reaches the following conclusions: 1) the Indosinian orogeny and Yanshanian orogeny are independent orogenic cycles; 2) there are mainly two Mo metallogenic epochs in Yanshanian era: about 180 Ma and about 130 Ma; and 3) about four regional compression-thrust events can be recognized: after J1, after J2, after J3 and after K1. So, the formation of Mo-deposits of the Yanshanian was under the background of compression-thrust, rather than the background of continental rift by extension of lithosphere.