Normal style="MARGIN: 0cm 0cm 0pt">The east-west Paleozoic normal faults are well developed in South Guizhou, as well as the Mesozoic and Cenozoic of the north-south thrust faults and folds. According to the planar distribution of the strata, fold and fault, field observation and interpretation of seismic profiles, the constraints of Paleozoic normal faults on structural characteristics are studied, combined with the thrust of Xuefeng Uplift. The results show that the Paleozoic east-west normal faults took effect as the transfer zone during the process of Mesozoic and Cenozoic deformation.