Several techniques, including GC, GC-MS and GC-IRMS, are used to study the molecular geochemistry and origin of oil (filled joint and cavern in limestone) of T1f1 in the Changjianggou profile of the northwest of the Sichuan Basin. The data show that the petroleum δ13C values for bulk oil and group compositions are less than -30 ‰. On the basis of regional geology, source rock characteristics of T1f1, geochemical characteristics of petroleum and oil-source correlation, the authors consider that the crude petroleum is a product of Cambrian source rock at the oil generation peak and the occurrence of crude petroleum in the limestone cave and seam is a result of tectonic destroys after the early oil accumulation.