The sequence stratigraphy and sedimentary characteristics are dealt with for the block M in the Niger delta, Nigeria on the basis of high-resolution sequence stratigraphic theory. Nine long-term cycles are discriminated on the basis of cycle boundary and types. The types and spatio-temporal evolution of deltas in response to the sequences and systems tracts are discussed in the light of regional tectonics, sedimentary background and sediment supply. Finally this paper gives a summary of cycle associations and stacking patterns of the sedimentary microfacies.