Geochemical blocks and their-inner structure of Fujian Province were analyzed in this paper. Geochemical blocks were delineated by 10 km×10 km window data based on 1∶200 000 regional geochemical surveys. Potential reserves of gold were estimated based on geochemical quantitative assessment model. The internal structure of the geochemical blocks for certain element may reveal its ways of concentration and formation in the regional geochemical anomalies. Predictive evaluation was carried out for major gold regional geochemical anomalies, which might be the potential areas for follow-up exploration.