The Shujiadian intrusion is located in the transition part between the Tongling faulting uplift and the Fanchang faulting basin in the Middle-Lower Reaches of Yangtze River. This paper studied LA-ICPMS U-Pb dating data of the zircons from pyroxene diorite, and its geochemical compositions and Pb isotope, so as to probe the geochronology, source and evolution of magmas, and tectonic setting of the Shujiadian intrusion. The results indicate that the age of the Shujiadian intrusion is (139.2±2.1) Ma (MSWD=2.3, n=12), suggesting that it is part of the magmatic system in the Tongling area, but not the Fanchang volcanic basin. Pyroxene diorite belongs to high potassium series.