pan lang="EN-US">The Jiaochong Au-S ore deposit is located in the Tongling ore concentration area along the middle-lower reaches of the Yangtze River. The ore body mainly occurs in the Lower Permian Qixia Formation. Based on an analysis of geological and ore- forming conditions, this paper systematically focuses on the composition characteristics of S, Pb isotopes in the sulfide ore minerals, and also discusses the sources of the ore-forming materials. Studies have shown that the composition of S isotope in sulfide ore minerals has a narrow variation range, and the pan>pan style="font-family: 宋体; mso-ascii-font-family: calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">δpan>pan lang="EN-US">34Span>pan style="font-family: 宋体; mso-ascii-font-family: calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">∑pan>pan lang="EN-US">s in the ore-forming hydrothermal system is about 4.0pan>pan style="font-family: 宋体; mso-ascii-font-family: calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">‰pan>pan lang="EN-US">. It is inferred that the S was genetically closely related to the magmatic sulfur. The isotopic compositions of ore lead vary greatly and belong to anomalous lead. Finally, through the chart of Zartmanpan>pan style="font-family: 宋体; mso-ascii-font-family: calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">'pan>pan lang="EN-US">s Pb evolutionary tectionic settings and pan>pan style="font-family: 宋体; mso-ascii-font-family: calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">△γpan>pan lang="EN-US">-pan>pan style="font-family: 宋体; mso-ascii-font-family: calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">△βpan>pan lang="EN-US"> diagram of genetic classification, the authors considerthat the ore-forming materials of the ore deposit were closely related to the magmatism and derived from the mixed sources of the upper continental crust and the mantle. The authors sincerely hope that these data can provide some help for the study of ore deposits related to granodiorite of the Tongling ore concenteation area.pan>