Four cross-deep seismic reflection profiles at the Luzhong iron-polymetallic deposits in the Lower and Middle Yangtze Reaches were performed by the Chinese Academy of Geological Sicences (CAGS) before the Chinese New Year of 2007. The results indicate that the long- offset first arrival travel-time tomography method can provide abundant crustal shallow structure information (0~ 1 000 m) for the study of prospect for the deep concealed deposits and the potential prospecting direction for iron-polymetallic deposits in the Luzhong area, Anhui province.