The structural characteristics of strike-slip fault in the northern slope of Tazhong area are analyzed. The controls of strike-slip faults on hydrocarbon reservoir are investigated. The result shows that there were five-period activities of the strike-slip faults since Ordovician. The formation and evolution of the strike-slip faults control the vertical depth and lateral distribution pattern of the carbonate reservoir of the Lower Ordovician. The multistage active strike-slip faults serve as good channels for hydrocarbon vertical migration. The local structural highs at intersections of long-term active strike-slip faults and thrust faults will be the favorable areas of hydrocarbon migration and accumulation.