To predict the quality of the low permeability reservoir of the Member 3 and Member 4 of the Quantou Formation in the Northern Songliao Basin, the diageneses of the clastic rocks were divided into early diagenetic stage A, early diagenetic stage B, middle diagenetic stage A1, middle diagenetic stage A21, middle diagenetic stage A22 and middle diagenetic stage B. The results of the statistical data show that diageneses have apparent controls on the physical property and oil saturation of the reservoirs, and the sand bodies of any sedimentary facies cannot produce commercial oil and gas flows in middle diagenetic stage B, and only the porosity of main river channel sand bodies is higher than the porosity cutoff of commercial oil and gas reservoir.