///Located in Beishan rift in the northeastern part of Tarim plate, the Pobei No.10 mafic-ultramafic body intruded into Early Carboniferous Hongliuyuan Formation. According to its emplacement strata, it was previously thought that this intrusive body was formed in Late Carboniferous-Early Permian. The authors performed dating by using such techniques as zircon U-Pb, disseminated ores Re-Os and Sr-Nd isotopic tracer with the purpose of systematic determination of the magmatic and mineralization ages, on such a basis, discussed the metallogenic significance of systematic differences between the ages dated by different isotopic systems. Because of heterogeneity in initial 187Os/188Os ratios of disseminated ores caused by crust contamination, the apparent dates older than the true age were obtained. Cu-Ni mineralization shows a close time-space relationship with the mafic-ultramafic intrusive body, implying a product of magmatic liquation. It is therefore concluded that the intrusion of Pobei No.10 mafic-ultramafic rock body and the related mineralization occurred in a post-orogenic dynamic setting in Late Carboniferous-Early Permian.