Based on the technical requirements for inorganic element analysis in the national 1∶50 000 ～1∶250 000 investigation and evaluation of groundwater pollution survey project, quality control samples for inorganic multielement analysis of groundwater were prepared. The matrixes of the samples were taken from natural groundwater and the components for certification were added artificially. The homogeneity and stability of the samples were tested with satisfactory results. The quality control samples have been applied to the instrument calibration, evaluation of the analytical methods and quality control in inorganic multi-element analysis in groundwater samples.