The Jinding Zn-Pb deposit, Yunnan, China, is so far the largest Zn-Pb deposit in China, the youngest and only giant Zn-Pb deposit hosted in continental sedimentary rocks in the world. Bitumen and heavy oil were often observed in the Jinding Zn-Pb deposit. The bitumen in the Jinding Zn-Pb ores hosted in the breccia-bearing sandstones and sandy breccias of the Paleocene Yunlong Formation has been dated by the Re-Os method in this paper, and an isochron age of (68±5) Ma (MSWD=9.2, n=6) has been obtained.  Therefore, the oil-gas reservoir in the Jinding ore district was formed earlier than the Zn-Pb mineralization. The formation of the oil-gas reservoir and the Zn-Pb deposit may have been a continuous geologic process, and the oil-gas reservoir was one of the basic conditions of Zn-Pb mineralization in the Jinding ore district. The oil-gas reservoir was destructed by the mineralization process.