In this paper, the health risk of the industrial zone in Hutuo River alluvial plain has been analyzed according to the impact for calculation results after Volatile Organic Compounds are boiled, and the Health Risk Assessment Model made by U.S. At the same time, the residual rate of TF after boiling has been added into the model. The results show that the typical detected organic pollutants in this area are chloroform, carbon tetrachloride, together with trichloroethylene and tetrachloroethene, they are mainly from industrial sources probably. The main contribution pollutants are chloroform and carbon tetrachloride. It’s suggested to use and drink boiled water, and to keep the air flow in workshop and work space in order to reduce health risks.