In this paper some technical questions, such as casing program, drilling tools and their match relation and cementing for the drilling operation of ultra-deep geological core hole have been discussed. The influence of these technical factors on the risk and economics of drilling operation of ultra-deep geological core holes are analyzed. On the basis of analytical study, proposals on the casing program, drilling tool match relation, ultra-deep drill string and casing string schemes and cementing program for the drilling of ultra-deep geological core holes are put forward.