The interaction between tectonics and climate on landform has sparked much interest over years. Based on SRTM-DEM data, this paper withdraws the measuring indicators of the landform and hypsometric integral from the third order basins and some of the second order basins in the Golmud river drainage basin using GIS spatial analysis, discusses the area and space dependence for hypsometric integral, and presents its significance in indicating tectonics, lithology and the degree of glacial erosion. The results show: the HI value depends on area and space; the southern fault of east Kunlun (F4)-Xidatan (F3) fault can be divided into two parts, the east and the west, by the Kunlun Pass; both of them show similar scenario that the activity decrease from the center to the sides; there is no apparent change in the activity of the central fault of east Kunlun (F1).