Based on the earthquake catalogue of the MS8.0 Wenchuan earthquake, the temporal and spatial distributions of seismic sequence of 1 613 aftershocks with MS≥3 from May 12th, 2008 to March 1st, 2010 were analyzed. The results showed that the aftershocks of the MS8.0 Wenchuan Earthquake could be divided into seven stages, and the 18 days after principal shock should be the alert time for the strong aftershock. The b value of seismic sequence was 0.751, which confirmed the view “the greater magnitude, the higher b value”. The p value of seismic sequence was 1.117, which was considerable to global seismic attenuation rate. The distribution of aftershocks expanded along northeast direction of Longmen Mountain Fault, and was obviously zonal.