The Pb-Zn-Cu ore belts in the northern part of West Kunlun are important Pb-Zn ore belts in China. In this paper, the authors investigated the correlation between mineralization distribution and the fault system through remote sensing image interpretation on the alteration information and comparison with known deposits. The results show that the Pb-Zn-Cu ore belts in the northern part of West Kunlun orogen appear in the areas with high tectonic activities,and are subjected to Middle Devonian and Lower Carboniferous strata. Therefore, the delimitation of metallogenic prognosis areas is under the limitation of mineralized alteration degree, tectonic activity intensity and the distribution ranges of the ore-bearing layers.